| Protein: | KPNA2 |
| Organism: | Homo sapiens |
| Length: | 529 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for KPNA2.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..529] | [1..529] |
|
|
0.0 | [1..529] | [1..529] |
|
|
0.0 | [1..529] | [1..529] |
|
|
0.0 | [1..529] | [1..529] |
|
|
0.0 | [1..529] | [1..529] |
|
|
0.0 | [1..529] | [1..529] |
|
Region A: Residues: [1-54] |
1 11 21 31 41 51
| | | | | |
1 MSTNENANTP AARLHRFKNK GKDSTEMRRR RIEVNVELRK AKKDDQMLKR RNVS
|
| Detection Method: |  |
| Confidence: | 2.49 |
| Match: | 1wa5B |
| Description: | Crystal structure of the exportin Cse1p complexed with its cargo ( Kap60p) and RanGTP |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [55-529] |
1 11 21 31 41 51
| | | | | |
1 SFPDDATSPL QENRNNQGTV NWSVDDIVKG INSSNVENQL QATQAARKLL SREKQPPIDN 60
61 IIRAGLIPKF VSFLGRTDCS PIQFESAWAL TNIASGTSEQ TKAVVDGGAI PAFISLLASP 120
121 HAHISEQAVW ALGNIAGDGS VFRDLVIKYG AVDPLLALLA VPDMSSLACG YLRNLTWTLS 180
181 NLCRNKNPAP PIDAVEQILP TLVRLLHHDD PEVLADTCWA ISYLTDGPNE RIGMVVKTGV 240
241 VPQLVKLLGA SELPIVTPAL RAIGNIVTGT DEQTQVVIDA GALAVFPSLL TNPKTNIQKE 300
301 ATWTMSNITA GRQDQIQQVV NHGLVPFLVS VLSKADFKTQ KEAVWAVTNY TSGGTVEQIV 360
361 YLVHCGIIEP LMNLLTAKDT KIILVILDAI SNIFQAAEKL GETEKLSIMI EECGGLDKIE 420
421 ALQNHENESV YKASLSLIEK YFSVEEEEDQ NVVPETTSEG YTFQVQDGAP GTFNF
|
| Detection Method: | |
| Confidence: | 103.0 |
| Match: | 1q1sC |
| Description: | Mouse Importin alpha- phosphorylated SV40 CN peptide complex |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| protein transporter activity | 4.58709163830613 | bayes_pls_golite062009 |
| nuclear export signal receptor activity | 3.48172991171337 | bayes_pls_golite062009 |
| binding | 3.0667965351474 | bayes_pls_golite062009 |
| actin binding | 2.8014924948341 | bayes_pls_golite062009 |
| nucleic acid binding | 2.74745843355294 | bayes_pls_golite062009 |
| protein transmembrane transporter activity | 2.74547353635661 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 2.61566088685247 | bayes_pls_golite062009 |
| transporter activity | 2.48700774379895 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 2.26725422172281 | bayes_pls_golite062009 |
| transcription regulator activity | 2.16673352512615 | bayes_pls_golite062009 |
| DNA binding | 1.95242774903625 | bayes_pls_golite062009 |
| nuclear localization sequence binding | 1.91487015967262 | bayes_pls_golite062009 |
| protein binding | 1.73688475473996 | bayes_pls_golite062009 |
| molecular transducer activity | 1.32874350341969 | bayes_pls_golite062009 |
| signal transducer activity | 1.32874350341969 | bayes_pls_golite062009 |
| transmembrane transporter activity | 1.28481004323799 | bayes_pls_golite062009 |
| transcription factor activity | 1.20660383756339 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 1.09652988954158 | bayes_pls_golite062009 |
| signal sequence binding | 0.57106697498903 | bayes_pls_golite062009 |
| RNA binding | 0.40024158562931 | bayes_pls_golite062009 |
| structural molecule activity | 0.279926218252647 | bayes_pls_golite062009 |
| importin-alpha export receptor activity | 0.259676026705859 | bayes_pls_golite062009 |
| active transmembrane transporter activity | 0.252495966234234 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 0.248585912061178 | bayes_pls_golite062009 |
| primary active transmembrane transporter activity | 0.226380819487924 | bayes_pls_golite062009 |
| P-P-bond-hydrolysis-driven transmembrane transporter activity | 0.217517113570989 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances | 0.178770060806735 | bayes_pls_golite062009 |
| ATPase activity, coupled to movement of substances | 0.175241020572885 | bayes_pls_golite062009 |
| ATPase activity, coupled to transmembrane movement of substances | 0.174922130116569 | bayes_pls_golite062009 |
| transcription activator activity | 0.160275383613705 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 0.100181463251306 | bayes_pls_golite062009 |
| pyrophosphatase activity | 0.0635404099346928 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides | 0.0548082069333885 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 0.052195223119721 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 0.0405268469927988 | bayes_pls_golite062009 |
| transcription factor binding | 0.0221966060394205 | bayes_pls_golite062009 |
