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View Structure Prediction Details

Protein: gi|119574692, gi...
Organism: Homo sapiens
Length: 715 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|119574692, gi....

Description E-value Query
Range
Subject
Range
gi|109089499 - gi|109089499|ref|XP_001110939.1| PREDICTED: similar to DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 iso...
0.0 [1..715] [69..783]
gi|114630811 - gi|114630811|ref|XP_507825.2| PREDICTED: DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Pan troglodytes]
0.0 [4..715] [53..783]
gi|11890755 - gi|11890755|gb|AAF78930.2|AAF78930 RNA helicase II/Gu protein [Homo sapiens]
0.0 [1..715] [1..715]
gi|73953311 - gi|73953311|ref|XP_851746.1| PREDICTED: similar to Nucleolar RNA helicase II (Nucleolar RNA helicase...
0.0 [16..715] [85..784]
DDX21_RAT - Nucleolar RNA helicase 2 OS=Rattus norvegicus GN=Ddx21 PE=2 SV=1
0.0 [4..715] [71..782]
gi|21410145 - gi|21410145|gb|AAH30895.1| Ddx21 protein [Mus musculus]
0.0 [35..715] [12..689]

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Predicted Domain #1
Region A:
Residues: [1-117]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNSPKSKKAK KKEEPSQNDI SPKTKSLRKK KEPIEKKVVS SKTKKVTKNE EPSEEEIDAP  60
   61 KPKKMKKEKE MNGETREKSP KLKNGFPHPE PDCNPSEAAS EESNSEIEQE IPVEQKE

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.67
Match: 2j63A
Description: No description for 2j63A was found.

Predicted Domain #2
Region A:
Residues: [118-337]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GAFSNFPISE ETIKLLKGRG VTFLFPIQAK TFHHVYSGKD LIAQARTGTG KTFSFAIPLI  60
   61 EKLHGELQDR KRGRAPQVLV LAPTRELANQ VSKDFSDITK KLSVACFYGG TPYGGQFERM 120
  121 RNGIDILVGT PGRIKDHIQN GKLDLTKLKH VVLDEVDQML DMGFADQVEE ILSVAYKKDS 180
  181 EDNPQTLLFS ATCPHWVFNV AKKYMKSTYE QVDLIGKKTQ 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 36.522879
Match: 2gxqA
Description: No description for 2gxqA was found.

Predicted Domain #3
Region A:
Residues: [338-498]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KTAITVEHLA IKCHWTQRAA VIGDVIRVYS GHQGRTIIFC ETKKEAQELS QNSAIKQDAQ  60
   61 SLHGDIPQKQ REITLKGFRN GSFGVLVATN VAARGLDIPE VDLVIQSSPP KDVESYIHRS 120
  121 GRTGRAGRTG VCICFYQHKE EYQLVQVEQK AGIKFKRIGV P

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 22.09691
Match: 2hjvA
Description: No description for 2hjvA was found.

Predicted Domain #4
Region A:
Residues: [499-715]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SATEIIKASS KDAIRLLDSV PPTAISHFKQ SAEKLIEEKG AVEALAAALA HISGATSVDQ  60
   61 RSLINSNVGF VTMILQCSIE MPNISYAWKE LKEQLGEEID SKVKGMVFLK GKLGVCFDVP 120
  121 TASVTEIQEK WHDSRRWQLS VATEQPELEG PREGYGGFRG QREGSRGFRG QRDGNRRFRG 180
  181 QREGSRGPRG QRSGGGNKSN RSQNKGQKRS FSKAFGQ

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 3.21
Match: 2e29A
Description: No description for 2e29A was found.

Predicted functions:

Term Confidence Notes
translation initiation factor activity 8.25448175613623 bayes_pls_golite062009
6.40066880991253 bayes_pls_golite062009
RNA binding 6.32219487559982 bayes_pls_golite062009
translation regulator activity 4.90183970829236 bayes_pls_golite062009
mRNA binding 4.87640532914983 bayes_pls_golite062009
translation factor activity, nucleic acid binding 4.72415388070659 bayes_pls_golite062009
nucleic acid binding 4.65259034341669 bayes_pls_golite062009
structural molecule activity 4.2958490777925 bayes_pls_golite062009
RNA cap binding 4.1452868296365 bayes_pls_golite062009
binding 3.48033873254013 bayes_pls_golite062009
telomeric DNA binding 3.14144520000442 bayes_pls_golite062009
snRNA binding 2.99850361909067 bayes_pls_golite062009
poly-pyrimidine tract binding 2.7133834347239 bayes_pls_golite062009
single-stranded RNA binding 2.55628738360472 bayes_pls_golite062009
transcription regulator activity 2.2045206027152 bayes_pls_golite062009
DNA binding 1.99030664201171 bayes_pls_golite062009
U1 snRNA binding 1.97699928565988 bayes_pls_golite062009
structure-specific DNA binding 1.33820479438671 bayes_pls_golite062009
single-stranded DNA binding 1.28888975042723 bayes_pls_golite062009
transcription repressor activity 1.26023364760328 bayes_pls_golite062009
cytoskeletal protein binding 1.13517096660218 bayes_pls_golite062009
transcription factor activity 1.09958329302628 bayes_pls_golite062009
protein binding 1.05805521997665 bayes_pls_golite062009
mRNA 5'-UTR binding 0.953943296217791 bayes_pls_golite062009
transcription elongation regulator activity 0.950588445732171 bayes_pls_golite062009
snoRNA binding 0.749770142991192 bayes_pls_golite062009
transporter activity 0.651859441112123 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.633093884585572 bayes_pls_golite062009
transmembrane transporter activity 0.514515120448404 bayes_pls_golite062009
mRNA 3'-UTR binding 0.462558743683805 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.438822250839508 bayes_pls_golite062009
tubulin binding 0.411965381384795 bayes_pls_golite062009
sequence-specific DNA binding 0.327072171076297 bayes_pls_golite062009
microtubule binding 0.26848788775744 bayes_pls_golite062009
substrate-specific transporter activity 0.191850978900584 bayes_pls_golite062009
translation repressor activity, nucleic acid binding 0.147208072406136 bayes_pls_golite062009
ligase activity 0.115699011007988 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.105881213754909 bayes_pls_golite062009
pyrophosphatase activity 0.0694221760244125 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.0607402568023739 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.0581257157312914 bayes_pls_golite062009
protein phosphatase 2B binding 0.0244897898877268 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle