| Protein: | MCM6 |
| Organism: | Homo sapiens |
| Length: | 821 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MCM6.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..821] | [1..821] |
|
|
0.0 | [1..821] | [1..821] |
|
|
0.0 | [1..821] | [1..821] |
|
|
0.0 | [1..821] | [135..955] |
|
|
0.0 | [1..821] | [1..821] |
|
|
0.0 | [1..821] | [1..821] |
|
|
0.0 | [1..821] | [1..821] |
|
|
0.0 | [1..821] | [1..821] |
|
Region A: Residues: [1-84] |
1 11 21 31 41 51
| | | | | |
1 MDLAAAAEPG AGSQHLEVRD EVAEKCQKLF LDFLEEFQSS DGEIKYLQLA EELIRPERNT 60
61 LVVSFVDLEQ FNQQLSTTIQ EEFY
|
| Detection Method: |  |
| Confidence: | 31.69897 |
| Match: | 1ltlA |
| Description: | DNA replication initiator (cdc21/cdc54) N-terminal domain |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [85-610] |
1 11 21 31 41 51
| | | | | |
1 RVYPYLCRAL KTFVKDRKEI PLAKDFYVAF QDLPTRHKIR ELTSSRIGLL TRISGQVVRT 60
61 HPVHPELVSG TFLCLDCQTV IRDVEQQFKY TQPNICRNPV CANRRRFLLD TNKSRFVDFQ 120
121 KVRIQETQAE LPRGSIPRSL EVILRAEAVE SAQAGDKCDF TGTLIVVPDV SKLSTPGARA 180
181 ETNSRVSGVD GYETEGIRGL RALGVRDLSY RLVFLACCVA PTNPRFGGKE LRDEEQTAES 240
241 IKNQMTVKEW EKVFEMSQDK NLYHNLCTSL FPTIHGNDEV KRGVLLMLFG GVPKTTGEGT 300
301 SLRGDINVCI VGDPSTAKSQ FLKHVEEFSP RAVYTSGKAS SAAGLTAAVV RDEESHEFVI 360
361 EAGALMLADN GVCCIDEFDK MDVRDQVAIH EAMEQQTISI TKAGVKATLN ARTSILAAAN 420
421 PISGHYDRSK SLKQNINLSA PIMSRFDLFF ILVDECNEVT DYAIARRIVD LHSRIEESID 480
481 RVYSLDDIRR YLLFARQFKP KISKESEDFI VEQYKHLRQR DGSGVT
|
| Detection Method: | |
| Confidence: | 24.39794 |
| Match: | 1ksfX |
| Description: | N-terminal, ClpS-binding domain of ClpA, an Hsp100 chaperone; ClpA, an Hsp100 chaperone, AAA+ modules |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| DNA clamp loader activity | 4.91429252297969 | bayes_pls_golite062009 |
| protein-DNA loading ATPase activity | 4.80695929076807 | bayes_pls_golite062009 |
| DNA-dependent ATPase activity | 2.72462789867829 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 2.66107861968804 | bayes_pls_golite062009 |
| binding | 2.64537357529343 | bayes_pls_golite062009 |
| DNA helicase activity | 2.2817164193758 | bayes_pls_golite062009 |
| nucleic acid binding | 2.21184938313192 | bayes_pls_golite062009 |
| pyrophosphatase activity | 2.13284212711072 | bayes_pls_golite062009 |
| DNA binding | 1.94055378599526 | bayes_pls_golite062009 |
| ATP-dependent DNA helicase activity | 1.88455339138556 | bayes_pls_golite062009 |
| transcription regulator activity | 1.83584389083042 | bayes_pls_golite062009 |
| helicase activity | 1.70242731830224 | bayes_pls_golite062009 |
| DNA replication origin binding | 1.62491387774159 | bayes_pls_golite062009 |
| microtubule motor activity | 1.35938517416356 | bayes_pls_golite062009 |
| purine NTP-dependent helicase activity | 1.19311444180077 | bayes_pls_golite062009 |
| ATP-dependent helicase activity | 1.19311444180077 | bayes_pls_golite062009 |
| catalytic activity | 1.00104173493322 | bayes_pls_golite062009 |
| DNA-directed DNA polymerase activity | 0.971476020912368 | bayes_pls_golite062009 |
| DNA polymerase activity | 0.928091843881235 | bayes_pls_golite062009 |
| structure-specific DNA binding | 0.782430219754236 | bayes_pls_golite062009 |
| transcription factor activity | 0.697256579145077 | bayes_pls_golite062009 |
| motor activity | 0.61636596887462 | bayes_pls_golite062009 |
| double-stranded DNA binding | 0.6071273686445 | bayes_pls_golite062009 |
| RNA helicase activity | 0.34746349346164 | bayes_pls_golite062009 |
| ATP-dependent RNA helicase activity | 0.30832907234141 | bayes_pls_golite062009 |
| RNA-dependent ATPase activity | 0.29532978396745 | bayes_pls_golite062009 |
| protein binding | 0.170837278876362 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 0.147579541298736 | bayes_pls_golite062009 |
| nucleotide binding | 0.114848452385726 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides | 0.113504049290503 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 0.111293884322157 | bayes_pls_golite062009 |
| purine nucleotide binding | 0.10713474095071 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 0.0916519414118148 | bayes_pls_golite062009 |
| ribonucleotide binding | 0.0915913646217636 | bayes_pls_golite062009 |
| structural constituent of ribosome | 0.089234257580272 | bayes_pls_golite062009 |
| 3'-5' DNA helicase activity | 0.0769112340058804 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 0.0272673919333979 | bayes_pls_golite062009 |
|
Region A: Residues: [611-821] |
1 11 21 31 41 51
| | | | | |
1 KSSWRITVRQ LESMIRLSEA MARMHCCDEV QPKHVKEAFR LLNKSIIRVE TPDVNLDQEE 60
61 EIQMEVDEGA GGINGHADSP APVNGINGYN EDINQESAPK ASLRLGFSEY CRISNLIVLH 120
121 LRKVEEEEDE SALKRSELVN WYLKEIESEI DSEEELINKK RIIEKVIHRL THYDHVLIEL 180
181 TQAGLKGSTE GSESYEEDPY LVVNPNYLLE D
|
| Detection Method: | |
| Confidence: | 24.522879 |
| Match: | 2dhrA |
| Description: | No description for 2dhrA was found. |
