| Protein: | VARS |
| Organism: | Homo sapiens |
| Length: | 1264 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for VARS.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..1264] | [1..1263] |
|
|
0.0 | [1..1264] | [1..1264] |
|
|
0.0 | [1..1264] | [1..1264] |
|
|
0.0 | [1..1264] | [1..1264] |
|
|
0.0 | [1..1264] | [1..1256] |
|
Region A: Residues: [1-293] |
1 11 21 31 41 51
| | | | | |
1 MSTLYVSPHP DAFPSLRALI AARYGEAGEG PGWGGAHPRI CLQPPPTSRT PFPPPRLPAL 60
61 EQGPGGLWVW GATAVAQLLW PAGLGGPGGS RAAVLVQQWV SYADTELIPA ACGATLPALG 120
121 LRSSAQDPQA VLGALGRALS PLEEWLRLHT YLAGEAPTLA DLAAVTALLL PFRYVLDPPA 180
181 RRIWNNVTRW FVTCVRQPEF RAVLGEVVLY SGARPLSHQP GPEAPALPKT AAQLKKEAKK 240
241 REKLEKFQQK QKIQQQQPPP GEKKPKPEKR EKRDPGVITY DLPTPPGEKK DVS
|
| Detection Method: |  |
| Confidence: | 31.221849 |
| Match: | 1ljrA |
| Description: | Class theta GST |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| oxidoreductase activity | 1.71351657881838 | bayes_pls_golite062009 |
| oxidoreductase activity, acting on NADH or NADPH | 1.05291982801016 | bayes_pls_golite062009 |
| NADH dehydrogenase activity | 1.0059256380115 | bayes_pls_golite062009 |
| NADH dehydrogenase (ubiquinone) activity | 0.862781254066789 | bayes_pls_golite062009 |
| NADH dehydrogenase (quinone) activity | 0.74734197007937 | bayes_pls_golite062009 |
| catalytic activity | 0.672192331361968 | bayes_pls_golite062009 |
| binding | 0.630214408223227 | bayes_pls_golite062009 |
| transcription regulator activity | 0.605488421122121 | bayes_pls_golite062009 |
| nucleic acid binding | 0.46030380837916 | bayes_pls_golite062009 |
| oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor | 0.18637981666133 | bayes_pls_golite062009 |
| DNA binding | 0.175092771820973 | bayes_pls_golite062009 |
| protein binding | 0.034515546627104 | bayes_pls_golite062009 |
|
Region A: Residues: [294-1264] |
1 11 21 31 41 51
| | | | | |
1 GPMPDSYSPR YVEAAWYPWW EQQGFFKPEY GRPNVSAANP RGVFMMCIPP PNVTGSLHLG 60
61 HALTNAIQDS LTRWHRMRGE TTLWNPGCDH AGIATQVVVE KKLWREQGLS RHQLGREAFL 120
121 QEVWKWKEEK GDRIYHQLKK LGSSLDWDRA CFTMDPKLSA AVTEAFVRLH EEGIIYRSTR 180
181 LVNWSCTLNS AISDIEVDKK ELTGRTLLSV PGYKEKVEFG VLVSFAYKVQ GSDSDEEVVV 240
241 ATTRIETMLG DVAVAVHPKD TRYQHLKGKN VIHPFLSRSL PIVFDEFVDM DFGTGAVKIT 300
301 PAHDQNDYEV GQRHGLEAIS IMDSRGALIN VPPPFLGLPR FEARKAVLVA LKERGLFRGI 360
361 EDNPMVVPLC NRSKDVVEPL LRPQWYVRCG EMAQAASAAV TRGDLRILPE AHQRTWHAWM 420
421 DNIREWCISR QLWWGHRIPA YFVTVSDPAV PPGEDPDGRY WVSGRNEAEA REKAAKEFGV 480
481 SPDKISLQQD EDVLDTWFSS GLFPLSILGW PNQSEDLSVF YPGTLLETGH DILFFWVARM 540
541 VMLGLKLTGR LPFREVYLHA IVRDAHGRKM SKSLGNVIDP LDVIYGISLQ GLHNQLLNSN 600
601 LDPSEVEKAK EGQKADFPAG IPECGTDALR FGLCAYMSQG RDINLDVNRI LGYRHFCNKL 660
661 WNATKFALRG LGKGFVPSPT SQPGGHESLV DRWIRSRLTE AVRLSNQGFQ AYDFPAVTTA 720
721 QYSFWLYELC DVYLECLKPV LNGVDQVAAE CARQTLYTCL DVGLRLLSPF MPFVTEELFQ 780
781 RLPRRMPQAP PSLCVTPYPE PSECSWKDPE AEAALELALS ITRAVRSLRA DYNLTRIRPD 840
841 CFLEVADEAT GALASAVSGY VQALASAGVV AVLALGAPAP QGCAVALASD RCSIHLQLQG 900
901 LVDPARELGK LQAKRVEAQR QAQRLRERRA ASGYPVKVPL EVQEADEAKL QQTEAELRKV 960
961 DEAIALFQKM L
|
| Detection Method: | |
| Confidence: | 1000.0 |
| Match: | 1gaxA |
| Description: | Valyl-tRNA synthetase (ValRS) C-terminal domain; Valyl-tRNA synthetase (ValRS) |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| ligase activity, forming aminoacyl-tRNA and related compounds | 7.16276509815667 | bayes_pls_golite062009 |
| ligase activity, forming carbon-oxygen bonds | 7.16276509815667 | bayes_pls_golite062009 |
| aminoacyl-tRNA ligase activity | 7.13957775963187 | bayes_pls_golite062009 |
| valine-tRNA ligase activity | 7.13767629265822 | bayes_pls_golite062009 |
| leucine-tRNA ligase activity | 7.03538514482698 | bayes_pls_golite062009 |
| isoleucine-tRNA ligase activity | 6.38633897147986 | bayes_pls_golite062009 |
| ligase activity | 6.11211476973434 | bayes_pls_golite062009 |
| glutamate-tRNA ligase activity | 2.63681738794687 | bayes_pls_golite062009 |
| methionine-tRNA ligase activity | 2.56893064485672 | bayes_pls_golite062009 |
| catalytic activity | 2.37674226834122 | bayes_pls_golite062009 |
| tyrosine-tRNA ligase activity | 1.88984817882585 | bayes_pls_golite062009 |
| arginine-tRNA ligase activity | 1.50161401062914 | bayes_pls_golite062009 |
| tryptophan-tRNA ligase activity | 1.14187887833901 | bayes_pls_golite062009 |
| cysteine-tRNA ligase activity | 0.844943947059557 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 0.625793556381714 | bayes_pls_golite062009 |
| binding | 0.485102284225571 | bayes_pls_golite062009 |
| nucleic acid binding | 0.449504767632354 | bayes_pls_golite062009 |
| nucleotidyltransferase activity | 0.2293846471193 | bayes_pls_golite062009 |
| glutamine-tRNA ligase activity | 0.118292082006187 | bayes_pls_golite062009 |
