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View Structure Prediction Details

Protein: CAR1
Organism: Saccharomyces cerevisiae
Length: 333 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CAR1.

Description E-value Query
Range
Subject
Range
gi|190407845 - gi|190407845|gb|EDV11110.1| arginase [Saccharomyces cerevisiae RM11-1a]
CAR1 - Arginase, responsible for arginine degradation, expression responds to both induction by arginine an...
ARGI_YEAST - Arginase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CAR1 PE=1 SV=1
9.0E-92 [1..333] [1..333]
ARGN2_XENLA - Arginase, non-hepatic 2 OS=Xenopus laevis GN=arg2-b PE=2 SV=1
2.0E-91 [13..331] [26..328]
ARGI1_PIG - Arginase-1 OS=Sus scrofa GN=ARG1 PE=2 SV=1
1.0E-90 [9..329] [2..305]
ARG1 - arginase, liver
gi|123982448, gi... - gi|123997109|gb|ABM86156.1| arginase, liver [synthetic construct], gi|123982448|gb|ABM82965.1| argin...
4.0E-90 [9..329] [2..305]

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Predicted Domain #1
Region A:
Residues: [1-333]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 METGPHYNYY KNRELSIVLA PFSGGQGKLG VEKGPKYMLK HGLQTSIEDL GWSTELEPSM  60
   61 DEAQFVGKLK MEKDSTTGGS SVMIDGVKAK RADLVGEATK LVYNSVSKVV QANRFPLTLG 120
  121 GDHSIAIGTV SAVLDKYPDA GLLWIDAHAD INTIESTPSG NLHGCPVSFL MGLNKDVPHC 180
  181 PESLKWVPGN LSPKKIAYIG LRDVDAGEKK ILKDLGIAAF SMYHVDKYGI NAVIEMAMKA 240
  241 VHPETNGEGP IMCSYDVDGV DPLYIPATGT PVRGGLTLRE GLFLVERLAE SGNLIALDVV 300
  301 ECNPDLAIHD IHVSNTISAG CAIARCALGE TLL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 612.519517
Match: 1hqxA_
Description: Arginase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
arginase activity 6.53441421234691 bayes_pls_golite062009
protein deacetylase activity 3.15425266272734 bayes_pls_golite062009
histone deacetylase activity 3.10913119405575 bayes_pls_golite062009
transcription regulator activity 2.52770743634098 bayes_pls_golite062009
hydrolase activity 2.11707868768295 bayes_pls_golite062009
transcription factor binding 2.06538836131829 bayes_pls_golite062009
binding 1.948738669065 bayes_pls_golite062009
deacetylase activity 1.91016771390707 bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 1.72243397396987 bayes_pls_golite062009
transcription repressor activity 1.70671280294121 bayes_pls_golite062009
catalytic activity 1.68836803454021 bayes_pls_golite062009
nucleic acid binding 1.59562744871718 bayes_pls_golite062009
DNA binding 1.55288325159263 bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines 1.01223037319069 bayes_pls_golite062009
transcription factor activity 0.882841288306625 bayes_pls_golite062009
protein binding 0.725535842743004 bayes_pls_golite062009
transcription cofactor activity 0.68008378742866 bayes_pls_golite062009
transcription corepressor activity 0.52929003055123 bayes_pls_golite062009
enzyme binding 0.39566582482721 bayes_pls_golite062009
specific transcriptional repressor activity 0.38389503761392 bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 0.0917282383800223 bayes_pls_golite062009
agmatinase activity 0.0741975192826536 bayes_pls_golite062009

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