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View Structure Prediction Details

Protein: ATP4
Organism: Saccharomyces cerevisiae
Length: 244 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ATP4.

Description E-value Query
Range		 Subject
Range
ATP5F1 - ATP synthase, H+ transporting, mitochondrial F0 complex, subunit B1
 4.0E-78 [14..242] [12..249]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
 9.0E-78 [14..242] [12..249]
ATPF_YEAST - ATP synthase subunit 4, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=AT...
gi|207340536 - gi|207340536|gb|EDZ68859.1| YPL078Cp-like protein [Saccharomyces cerevisiae AWRI1631]
gi|151942718 - gi|151942718|gb|EDN61064.1| F1F0 ATP synthase subunit b [Saccharomyces cerevisiae YJM789]
ATP4 - Subunit b of the stator stalk of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily c...
 3.0E-77 [1..244] [1..244]
AT5F1_RAT - ATP synthase F(0) complex subunit B1, mitochondrial OS=Rattus norvegicus GN=Atp5f1 PE=1 SV=1
 6.0E-77 [14..242] [12..249]
AT5F1_BOVIN, ATP... - (P13619) ATP synthase B chain, mitochondrial (EC 3.6.3.14), (P13619) ATP synthase B chain, mitochond...
 8.0E-75 [41..242] [1..207]
ATPsyn-b-PA - The gene ATP synthase, subunit b is referred to in FlyBase by the symbol Dmel\ATPsyn-b (CG8189, FBgn...
gi|220950888, gi... - gi|220959542|gb|ACL92314.1| ATPsyn-b-PA [synthetic construct], gi|220950888|gb|ACL87987.1| ATPsyn-b-...
 1.0E-72 [10..244] [5..241]
gi|23820959 - gi|23820959|gb|AAN39695.1| ATP synthase-like protein [Choristoneura parallela]
 2.0E-69 [9..242] [10..244]
gi|148234340, gi... - gi|6911053|gb|AAF31360.1| ATP synthase subunit B [Xenopus laevis], gi|28981424|gb|AAH48772.1| MGC533...
 2.0E-68 [14..241] [8..244]

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Predicted Domain #1
Region A:
Residues: [1-89] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSMSMGVRGL ALRSVSKTLF SQGVRCPSMV IGARYMSSTP EKQTDPKAKA NSIINAIPGN  60
   61 NILTKTGVLG TSAAAVIYAI SNELYVIND

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

    MCM
Score		 GO
Score		 GO
Term		 SCOP
Match		 SCOP Description
View Download 0.900 0.012 hydrogen ion transporting ATP synthase activity, rotational mechanism a.7.7 BAG domain

Predicted functions:

Term Confidence Notes
hydrogen ion transmembrane transporter activity 9.75824095339252 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 8.02996687028513 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 7.03421298777104 bayes_pls_golite062009
hydrogen-exporting ATPase activity, phosphorylative mechanism 6.33533983608004 bayes_pls_golite062009
cation transmembrane transporter activity 3.43905785379115 bayes_pls_golite062009
ion transmembrane transporter activity 3.40493178308083 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 3.11087315592201 bayes_pls_golite062009
transporter activity 2.33132024466294 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism 2.14184902122852 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of ions 1.91129736413093 bayes_pls_golite062009
nucleoside-triphosphatase activity 1.68240669590269 bayes_pls_golite062009
pyrophosphatase activity 1.61544861060476 bayes_pls_golite062009
ATPase activity 1.60552572277149 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 1.5982352071671 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 1.5958855657846 bayes_pls_golite062009
transmembrane transporter activity 1.51271412556287 bayes_pls_golite062009
substrate-specific transporter activity 1.35431931487507 bayes_pls_golite062009
binding 1.24770939036016 bayes_pls_golite062009
primary active transmembrane transporter activity 0.907643434530535 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 0.90151467619641 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 0.873541340643087 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances 0.870099443464063 bayes_pls_golite062009
ATPase activity, coupled to movement of substances 0.870012300409237 bayes_pls_golite062009
active transmembrane transporter activity 0.869408183980935 bayes_pls_golite062009
catalytic activity 0.67288476528593 bayes_pls_golite062009
hydrolase activity 0.636687378087875 bayes_pls_golite062009
protein binding 0.438049027037998 bayes_pls_golite062009
ATPase activity, coupled 0.423824294580682 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [90-244] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ESILLLTFLG FTGLVAKYLA PAYKDFADAR MKKVSDVLNA SRNKHVEAVK DRIDSVSQLQ  60
   61 NVAETTKVLF DVSKETVELE SEAFELKQKV ELAHEAKAVL DSWVRYEASL RQLEQRQLAK 120
  121 SVISRVQSEL GNPKFQEKVL QQSISEIEQL LSKLK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle