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Protein Overview: ATPsyn-b-PA

General Information:
Name(s) found: ATPsyn-b-PA / FBpp0076134 [FlyBase]
Description(s) found:
Found 25 descriptions.
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  • The gene ATP synthase, subunit b is referred to in FlyBase by the symbol Dmel\ATPsyn-b (CG8189, FBgn0019644). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:9723077..9724324. It has the cytological map location 67C5. Based on sequence similarity, it is predicted to have molecular function</span>: hydrogen-exporting ATPase activity, phosphorylative mechanism. There is experimental evidence that it is involved in the biological process</span>: phagocytosis, engulfment. 4 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 243 amino acids

    Gene Ontology:
    Cellular Component: mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) [ISS]
    lipid particle [IDA]
    Biological Process: proton transport [ISS][NAS]
    phagocytosis, engulfment [IMP]
    ATP synthesis coupled proton transport [IEA]
    Molecular Function: hydrogen-exporting ATPase activity, phosphorylative mechanism [ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFSRAALLTA QRPLTVAATR SAAAAAAPGG AIERRQRPEH PGKVRLGFLP EEWFQFFYNK  60
   61 TGVTGPYTFG VGLITYLCSK EIYVMEHEYY SGLSLGIMAI IAVKKLGPVI AKWADGEIDK 120
  121 IESEWKEGRE AELKVLSDAI EAEKKEQWRA DGALLLMEAK KENIALQLEA AFRERAMNVY 180
  181 SEVKRRLDYQ VECRHVERRL SQKHMVNWIT TNVLASISPQ QEKETLNKCI ADLSALALRV 240
  241 KSA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..243] PSI-BLAST 68.39794 No description for 2clyA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • hydrogen ion transmembrane transporter activity
    		•  9.75824095339252 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  8.02996687028513 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  7.03421298777104 bayes_pls_golite062009
  • hydrogen-exporting ATPase activity, phosphorylative mechanism
    		•  6.33533983608004 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  3.43905785379115 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  3.40493178308083 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  3.11087315592201 bayes_pls_golite062009
  • transporter activity
    		•  2.33132024466294 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
    		•  2.14184902122852 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of ions
    		•  1.91129736413093 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  1.68240669590269 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  1.61544861060476 bayes_pls_golite062009
  • ATPase activity
    		•  1.60552572277149 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  1.5982352071671 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  1.5958855657846 bayes_pls_golite062009
  • binding
    		•  1.55004523425024 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.51271412556287 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  1.35431931487507 bayes_pls_golite062009
  • protein binding
    		•  0.964424682848373 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  0.907643434530535 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  0.90151467619641 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  0.873541340643087 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  0.870099443464063 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  0.870012300409237 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.869408183980935 bayes_pls_golite062009
  • hydrolase activity
    		•  0.636687378087875 bayes_pls_golite062009
  • ATPase activity, coupled
    		•  0.423824294580682 bayes_pls_golite062009
  • catalytic activity
    		•  0.130280729190391 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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