| Protein: | EXO1 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 702 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for EXO1.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..702] | [1..702] |
|
|
0.0 | [1..552] | [1..541] |
|
|
0.0 | [1..597] | [1..604] |
|
|
0.0 | [1..544] | [1..532] |
|
|
0.0 | [1..539] | [1..523] |
|
Region A: Residues: [1-361] |
1 11 21 31 41 51
| | | | | |
1 MGIQGLLPQL KPIQNPVSLR RYEGEVLAID GYAWLHRAAC SCAYELAMGK PTDKYLQFFI 60
61 KRFSLLKTFK VEPYLVFDGD AIPVKKSTES KRRDKRKENK AIAERLWACG EKKNAMDYFQ 120
121 KCVDITPEMA KCIICYCKLN GIRYIVAPFE ADSQMVYLEQ KNIVQGIISE DSDLLVFGCR 180
181 RLITKLNDYG ECLEICRDNF IKLPKKFPLG SLTNEEIITM VCLSGCDYTN GIPKVGLITA 240
241 MKLVRRFNTI ERIILSIQRE GKLMIPDTYI NEYEAAVLAF QFQRVFCPIR KKIVSLNEIP 300
301 LYLKDTESKR KRLYACIGFV IHRETQKKQI VHFDDDIDHH LHLKIAQGDL NPYDFHQPLA 360
361 N
|
| Detection Method: |  |
| Confidence: | 188.30103 |
| Match: | 1a76__ |
| Description: | Flap endonuclease-1 (Fen-1 nuclease) |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| hydrolase activity, acting on ester bonds | 5.44893156272125 | bayes_pls_golite062009 |
| single-stranded DNA specific 3'-5' exodeoxyribonuclease activity | 4.19173394038227 | bayes_pls_golite062009 |
| flap endonuclease activity | 4.10438637013244 | bayes_pls_golite062009 |
| exonuclease activity | 3.55065728618765 | bayes_pls_golite062009 |
| endonuclease activity | 3.40075034200919 | bayes_pls_golite062009 |
| endodeoxyribonuclease activity | 3.29138075959109 | bayes_pls_golite062009 |
| deoxyribonuclease activity | 3.25110450559975 | bayes_pls_golite062009 |
| 5'-3' exonuclease activity | 3.19536858640519 | bayes_pls_golite062009 |
| nuclease activity | 2.50181033811809 | bayes_pls_golite062009 |
| hydrolase activity | 2.4418166499042 | bayes_pls_golite062009 |
| exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters | 2.3324415860722 | bayes_pls_golite062009 |
| 5'-3' exodeoxyribonuclease activity | 2.26658239783943 | bayes_pls_golite062009 |
| double-stranded DNA specific exodeoxyribonuclease activity | 2.09057967200253 | bayes_pls_golite062009 |
| nucleic acid binding | 2.02510018436829 | bayes_pls_golite062009 |
| exodeoxyribonuclease activity | 2.0005433655378 | bayes_pls_golite062009 |
| exodeoxyribonuclease activity, producing 5'-phosphomonoesters | 1.9833086883205 | bayes_pls_golite062009 |
| DNA binding | 1.93844174573408 | bayes_pls_golite062009 |
| binding | 1.86985246794396 | bayes_pls_golite062009 |
| ribonuclease activity | 1.84042322103694 | bayes_pls_golite062009 |
| 5'-flap endonuclease activity | 1.81850767854435 | bayes_pls_golite062009 |
| single-stranded DNA specific exodeoxyribonuclease activity | 1.61167902830399 | bayes_pls_golite062009 |
| damaged DNA binding | 1.42836853175021 | bayes_pls_golite062009 |
| catalytic activity | 1.37534898662234 | bayes_pls_golite062009 |
| ribonuclease H activity | 1.29762010718359 | bayes_pls_golite062009 |
| structure-specific DNA binding | 1.16717206930423 | bayes_pls_golite062009 |
| single-stranded DNA specific 5'-3' exodeoxyribonuclease activity | 1.15948049342759 | bayes_pls_golite062009 |
| single-stranded DNA specific endodeoxyribonuclease activity | 1.10463550341524 | bayes_pls_golite062009 |
| endodeoxyribonuclease activity, producing 5'-phosphomonoesters | 0.901965019685213 | bayes_pls_golite062009 |
| endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters | 0.512509234493511 | bayes_pls_golite062009 |
| protein binding | 0.389020243587168 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 0.319622686426271 | bayes_pls_golite062009 |
| endoribonuclease activity | 0.312346277055223 | bayes_pls_golite062009 |
| DNA polymerase activity | 0.250070491623222 | bayes_pls_golite062009 |
| DNA-directed DNA polymerase activity | 0.233683378650593 | bayes_pls_golite062009 |
| double-stranded DNA binding | 0.0978227645302046 | bayes_pls_golite062009 |
| 3'-5'-exodeoxyribonuclease activity | 0.0205129272358 | bayes_pls_golite062009 |
|
Region A: Residues: [362-427] |
1 11 21 31 41 51
| | | | | |
1 REHKLQLASK SNIEFGKTNT TNSEAKVKPI ESFFQKMTKL DHNPKVANNI HSLRQAEDKL 60
61 TMAIKR
|
| Detection Method: | |
| Confidence: | 3.0 |
| Match: | 1d9dA_ |
| Description: | Exonuclease domain of prokaryotic DNA polymerase; DNA polymerase I (Klenow fragment) |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [428-702] |
1 11 21 31 41 51
| | | | | |
1 RKLSNANVVQ ETLKDTRSKF FNKPSMTVVE NFKEKGDSIQ DFKEDTNSQS LEEPVSESQL 60
61 STQIPSSFIT TNLEDDDNLS EEVSEVVSDI EEDRKNSEGK TIGNEIYNTD DDGDGDTSED 120
121 YSETAESRVP TSSTTSFPGS SQRSISGCTK VLQKFRYSSS FSGVNANRQP LFPRHVNQKS 180
181 RGMVYVNQNR DDDCDDNDGK NQITQRPSLR KSLIGARSQR IVIDMKSVDE RKSFNSSPIL 240
241 HEESKKRDIE TTKSSQARPA VRSISLLSQF VYKGK
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
