| Protein: | RRP40 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 240 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RRP40.
| Description | E-value | Query Range |
Subject Range |
|
|
9.0E-59 | [12..229] | [27..239] |
|
|
7.0E-57 | [5..233] | [17..237] |
|
|
1.0E-54 | [3..224] | [11..231] |
|
|
4.0E-51 | [2..222] | [24..231] |
|
|
8.0E-51 | [2..239] | [8..227] |
|
|
4.0E-49 | [2..239] | [8..227] |
|
|
4.0E-49 | [3..229] | [2..218] |
|
|
6.0E-49 | [2..237] | [9..236] |
|
Region A: Residues: [1-146] |
1 11 21 31 41 51
| | | | | |
1 MSTFIFPGDS FPVDPTTPVK LGPGIYCDPN TQEIRPVNTG VLHVSAKGKS GVQTAYIDYS 60
61 SKRYIPSVND FVIGVIIGTF SDSYKVSLQN FSSSVSLSYM AFPNASKKNR PTLQVGDLVY 120
121 ARVCTAEKEL EAEIECFDST TGRDAG
|
| Detection Method: |  |
| Confidence: | 8.74 |
| Match: | 1e3hA |
| Description: | Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 1 and 4; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 6; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 2 and 5 |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [147-240] |
1 11 21 31 41 51
| | | | | |
1 FGILEDGMII DVNFNFARQL LFNNDFPLLK VLAAHTKFEV AIGLNGKIWV KCEELSNTLA 60
61 CYRTIMECCQ KNDTAAFKDI AKRQFKEILT VKEE
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.680 | 0.283 | mRNA catabolic process | d.58.7 | RNA-binding domain, RBD |
| View | Download | 0.697 | 0.062 | mRNA catabolic process | d.51.1 | Eukaryotic type KH-domain (KH-domain type I) |
| View | Download | 0.845 | 0.025 | mRNA catabolic process | d.58.10 | Acylphosphatase-like |
| View | Download | 0.664 | 0.007 | mRNA catabolic process | d.58.49 | YajQ-like |
| View | Download | 0.663 | N/A | N/A | d.58.7 | RNA-binding domain, RBD |
| View | Download | 0.637 | N/A | N/A | d.58.7 | RNA-binding domain, RBD |
| View | Download | 0.621 | N/A | N/A | d.141.1 | Ribosomal protein L6 |
| View | Download | 0.606 | N/A | N/A | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.574 | N/A | N/A | d.58.48 | MTH1187-like |
| View | Download | 0.566 | N/A | N/A | c.51.3 | B12-dependend dehydatases associated subunit |
| View | Download | 0.563 | N/A | N/A | d.129.1 | TATA-box binding protein-like |
| View | Download | 0.557 | N/A | N/A | d.87.1 | FAD/NAD-linked reductases, dimerisation (C-terminal) domain |
| View | Download | 0.545 | N/A | N/A | d.58.17 | Metal-binding domain |
| View | Download | 0.544 | N/A | N/A | d.51.1 | Eukaryotic type KH-domain (KH-domain type I) |
| View | Download | 0.529 | N/A | N/A | d.58.49 | YajQ-like |
| View | Download | 0.528 | N/A | N/A | d.58.7 | RNA-binding domain, RBD |
| View | Download | 0.495 | N/A | N/A | a.24.7 | FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) |
| View | Download | 0.492 | N/A | N/A | d.58.25 | Killer toxin KP6 alpha-subunit |
| View | Download | 0.491 | N/A | N/A | a.12.1 | Kix domain of CBP (creb binding protein) |
| View | Download | 0.489 | N/A | N/A | d.141.1 | Ribosomal protein L6 |
| View | Download | 0.463 | N/A | N/A | d.58.3 | Protease propeptides/inhibitors |
| View | Download | 0.456 | N/A | N/A | d.58.36 | Sulfite reductase, domains 1 and 3 |
| View | Download | 0.448 | N/A | N/A | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.440 | N/A | N/A | d.74.2 | C-terminal domain of arginine repressor |
| View | Download | 0.432 | N/A | N/A | b.84.2 | Rudiment single hybrid motif |
| View | Download | 0.426 | N/A | N/A | a.6.1 | Putative DNA-binding domain |
| View | Download | 0.419 | N/A | N/A | d.58.11 | EF-G/eEF-2 domains III and V |
| View | Download | 0.416 | N/A | N/A | d.129.2 | Phosphoglucomutase, C-terminal domain |
| View | Download | 0.407 | N/A | N/A | d.58.18 | Regulatory domain in the aminoacid metabolism |
| View | Download | 0.407 | N/A | N/A | a.11.1 | Acyl-CoA binding protein |
| View | Download | 0.402 | N/A | N/A | d.95.1 | Glucose permease domain IIB |
| View | Download | 0.399 | N/A | N/A | a.156.1 | S13-like H2TH domain |
| View | Download | 0.398 | N/A | N/A | b.1.2 | Fibronectin type III |
| View | Download | 0.385 | N/A | N/A | a.39.1 | EF-hand |
| View | Download | 0.384 | N/A | N/A | d.58.5 | GlnB-like |
| View | Download | 0.383 | N/A | N/A | d.16.1 | FAD-linked reductases, C-terminal domain |
| View | Download | 0.382 | N/A | N/A | a.101.1 | Uteroglobin-like |
| View | Download | 0.374 | N/A | N/A | d.58.17 | Metal-binding domain |
| View | Download | 0.369 | N/A | N/A | d.16.1 | FAD-linked reductases, C-terminal domain |
| View | Download | 0.365 | N/A | N/A | a.49.1 | C-terminal domain of B transposition protein |
| View | Download | 0.322 | N/A | N/A | a.11.2 | Second domain of FERM |
| View | Download | 0.320 | N/A | N/A | d.58.3 | Protease propeptides/inhibitors |
| View | Download | 0.318 | N/A | N/A | a.57.1 | Protein HNS-dependent expression A; HdeA |
| View | Download | 0.317 | N/A | N/A | d.137.1 | Monooxygenase (hydroxylase) regulatory protein |
| View | Download | 0.317 | N/A | N/A | a.11.1 | Acyl-CoA binding protein |
| View | Download | 0.316 | N/A | N/A | a.4.2 | Methylated DNA-protein cysteine methyltransferase, C-terminal domain |
| View | Download | 0.308 | N/A | N/A | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| View | Download | 0.307 | N/A | N/A | a.39.1 | EF-hand |
| View | Download | 0.296 | N/A | N/A | d.129.1 | TATA-box binding protein-like |
| View | Download | 0.296 | N/A | N/A | d.58.17 | Metal-binding domain |
| View | Download | 0.295 | N/A | N/A | d.58.11 | EF-G/eEF-2 domains III and V |
| View | Download | 0.291 | N/A | N/A | a.118.9 | ENTH/VHS domain |
| View | Download | 0.290 | N/A | N/A | b.84.2 | Rudiment single hybrid motif |
| View | Download | 0.288 | N/A | N/A | a.29.4 | RecG, N-terminal domain |
| View | Download | 0.286 | N/A | N/A | a.118.14 | FliG |
| View | Download | 0.285 | N/A | N/A | d.58.1 | 4Fe-4S ferredoxins |
| View | Download | 0.283 | N/A | N/A | g.59.1 | Zinc-binding domain of translation initiation factor 2 beta |
| View | Download | 0.269 | N/A | N/A | d.95.2 | Homing endonucleases |
| View | Download | 0.267 | N/A | N/A | a.177.1 | Sigma2 domain of RNA polymerase sigma factors |
| View | Download | 0.263 | N/A | N/A | d.64.1 | eIF1-like |
| View | Download | 0.261 | N/A | N/A | a.48.3 | Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 |
| View | Download | 0.260 | N/A | N/A | a.60.1 | SAM/Pointed domain |
| View | Download | 0.258 | N/A | N/A | c.78.2 | Aspartate/glutamate racemase |
| View | Download | 0.255 | N/A | N/A | d.74.2 | C-terminal domain of arginine repressor |
| View | Download | 0.253 | N/A | N/A | d.58.5 | GlnB-like |
| View | Download | 0.251 | N/A | N/A | d.58.20 | NAD-binding domain of HMG-CoA reductase |
| View | Download | 0.250 | N/A | N/A | a.24.16 | Nucleotidyltransferase substrate binding subunit/domain |
| View | Download | 0.248 | N/A | N/A | d.110.4 | SNARE-like |
| View | Download | 0.246 | N/A | N/A | a.118.11 | Cytochrome c oxidase subunit E |
| View | Download | 0.245 | N/A | N/A | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.245 | N/A | N/A | d.118.1 | N-acetylmuramoyl-L-alanine amidase-like |
| View | Download | 0.244 | N/A | N/A | d.58.1 | 4Fe-4S ferredoxins |
| View | Download | 0.234 | N/A | N/A | a.35.1 | lambda repressor-like DNA-binding domains |
| View | Download | 0.228 | N/A | N/A | d.51.1 | Eukaryotic type KH-domain (KH-domain type I) |
| View | Download | 0.225 | N/A | N/A | c.47.1 | Thioredoxin-like |
| View | Download | 0.225 | N/A | N/A | d.58.7 | RNA-binding domain, RBD |
| View | Download | 0.223 | N/A | N/A | d.58.8 | Viral DNA-binding domain |
| View | Download | 0.223 | N/A | N/A | a.133.1 | Phospholipase A2, PLA2 |
| View | Download | 0.222 | N/A | N/A | d.58.4 | Dimeric alpha+beta barrel |
| View | Download | 0.219 | N/A | N/A | d.16.1 | FAD-linked reductases, C-terminal domain |
| View | Download | 0.216 | N/A | N/A | d.58.1 | 4Fe-4S ferredoxins |
| View | Download | 0.214 | N/A | N/A | a.3.1 | Cytochrome c |
| View | Download | 0.214 | N/A | N/A | d.87.1 | FAD/NAD-linked reductases, dimerisation (C-terminal) domain |
| View | Download | 0.212 | N/A | N/A | c.53.1 | Resolvase-like |
| View | Download | 0.209 | N/A | N/A | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.208 | N/A | N/A | d.141.1 | Ribosomal protein L6 |
| View | Download | 0.206 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.206 | N/A | N/A | a.26.1 | 4-helical cytokines |
| View | Download | 0.203 | N/A | N/A | d.58.17 | Metal-binding domain |
| View | Download | 0.203 | N/A | N/A | a.133.1 | Phospholipase A2, PLA2 |
| Term | Confidence | Notes |
| ribonuclease activity | 7.42330864261751 | bayes_pls_golite062009 |
| exoribonuclease activity | 6.76241588209982 | bayes_pls_golite062009 |
| exoribonuclease activity, producing 5'-phosphomonoesters | 6.73428326869965 | bayes_pls_golite062009 |
| 3'-5'-exoribonuclease activity | 5.13367897180134 | bayes_pls_golite062009 |
| 3'-5' exonuclease activity | 3.51306349336452 | bayes_pls_golite062009 |
| nucleic acid binding | 3.194200758646 | bayes_pls_golite062009 |
| exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters | 3.07263153665399 | bayes_pls_golite062009 |
| hydrolase activity, acting on ester bonds | 2.73968547121328 | bayes_pls_golite062009 |
| DNA binding | 2.71213098011194 | bayes_pls_golite062009 |
| exonuclease activity | 2.66053639652924 | bayes_pls_golite062009 |
| RNA binding | 2.41160981373213 | bayes_pls_golite062009 |
| binding | 2.24181355929217 | bayes_pls_golite062009 |
| structure-specific DNA binding | 1.81524862921454 | bayes_pls_golite062009 |
| single-stranded DNA binding | 1.62996999055328 | bayes_pls_golite062009 |
| structural constituent of ribosome | 1.4075750746354 | bayes_pls_golite062009 |
| aminoacyl-tRNA ligase activity | 1.35850109411274 | bayes_pls_golite062009 |
| ligase activity, forming carbon-oxygen bonds | 1.35845277283398 | bayes_pls_golite062009 |
| ligase activity, forming aminoacyl-tRNA and related compounds | 1.35845277283398 | bayes_pls_golite062009 |
| 1.2099360907571 | bayes_pls_golite062009 | |
| exoribonuclease II activity | 1.18248519339188 | bayes_pls_golite062009 |
| structural molecule activity | 1.06009055746922 | bayes_pls_golite062009 |
| transcription regulator activity | 0.996884322431837 | bayes_pls_golite062009 |
| hydrolase activity | 0.724860465280978 | bayes_pls_golite062009 |
| nuclease activity | 0.57381531077345 | bayes_pls_golite062009 |
| mRNA binding | 0.4162128308402 | bayes_pls_golite062009 |
| ligase activity | 0.346041081217685 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 0.32084431704638 | bayes_pls_golite062009 |
| transcription factor activity | 0.298729064067577 | bayes_pls_golite062009 |
| translation regulator activity | 0.22908707234671 | bayes_pls_golite062009 |
| translation factor activity, nucleic acid binding | 0.179682348023561 | bayes_pls_golite062009 |
| aspartate-tRNA ligase activity | 0.151650064901878 | bayes_pls_golite062009 |
| translation initiation factor activity | 0.11625379846973 | bayes_pls_golite062009 |
