| Protein: | DIS3 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 1001 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DIS3.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..1001] | [1..1001] |
|
|
0.0 | [20..1000] | [4..927] |
|
|
0.0 | [20..1000] | [4..969] |
|
|
0.0 | [22..1000] | [20..968] |
|
|
0.0 | [21..1000] | [5..944] |
|
|
0.0 | [20..1000] | [4..932] |
|
|
0.0 | [20..985] | [4..882] |
|
|
0.0 | [21..975] | [5..939] |
|
Region A: Residues: [1-325] |
1 11 21 31 41 51
| | | | | |
1 MSVPAIAPRR KRLADGLSVT QKVFVRSRNG GATKIVREHY LRSDIPCLSR SCTKCPQIVV 60
61 PDAQNELPKF ILSDSPLELS APIGKHYVVL DTNVVLQAID LLENPNCFFD VIVPQIVLDE 120
121 VRNKSYPVYT RLRTLCRDSD DHKRFIVFHN EFSEHTFVER LPNETINDRN DRAIRKTCQW 180
181 YSEHLKPYDI NVVLVTNDRL NREAATKEVE SNIITKSLVQ YIELLPNADD IRDSIPQMDS 240
241 FDKDLERDTF SDFTFPEYYS TARVMGGLKN GVLYQGNIQI SEYNFLEGSV SLPRFSKPVL 300
301 IVGQKNLNRA FNGDQVIVEL LPQSE
|
| Detection Method: |  |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [326-415] |
1 11 21 31 41 51
| | | | | |
1 WKAPSSIVLD SEHFDVNDNP DIEAGDDDDN NESSSNTTVI SDKQRRLLAK DAMIAQRSKK 60
61 IQPTAKVVYI QRRSWRQYVG QLAPSSVDPQ
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [416-823] |
1 11 21 31 41 51
| | | | | |
1 SSSTQNVFVI LMDKCLPKVR IRTRRAAELL DKRIVISIDS WPTTHKYPLG HFVRDLGTIE 60
61 SAQAETEALL LEHDVEYRPF SKKVLECLPA EGHDWKAPTK LDDPEAVSKD PLLTKRKDLR 120
121 DKLICSIDPP GCVDIDDALH AKKLPNGNWE VGVHIADVTH FVKPGTALDA EGAARGTSVY 180
181 LVDKRIDMLP MLLGTDLCSL KPYVDRFAFS VIWELDDSAN IVNVNFMKSV IRSREAFSYE 240
241 QAQLRIDDKT QNDELTMGMR ALLKLSVKLK QKRLEAGALN LASPEVKVHM DSETSDPNEV 300
301 EIKKLLATNS LVEEFMLLAN ISVARKIYDA FPQTAMLRRH AAPPSTNFEI LNEMLNTRKN 360
361 MSISLESSKA LADSLDRCVD PEDPYFNTLV RIMSTRCMMA AQYFYSGA
|
| Detection Method: | |
| Confidence: | 168.39794 |
| Match: | PF00773 |
| Description: | RNB-like protein |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
| Term | Confidence | Notes |
| ribonuclease activity | 7.42330864261751 | bayes_pls_golite062009 |
| exoribonuclease activity | 6.76241588209982 | bayes_pls_golite062009 |
| exoribonuclease activity, producing 5'-phosphomonoesters | 6.73428326869965 | bayes_pls_golite062009 |
| 3'-5'-exoribonuclease activity | 5.13367897180134 | bayes_pls_golite062009 |
| 3'-5' exonuclease activity | 3.51306349336452 | bayes_pls_golite062009 |
| nucleic acid binding | 3.194200758646 | bayes_pls_golite062009 |
| exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters | 3.07263153665399 | bayes_pls_golite062009 |
| binding | 2.83465364476231 | bayes_pls_golite062009 |
| hydrolase activity, acting on ester bonds | 2.73968547121328 | bayes_pls_golite062009 |
| DNA binding | 2.71213098011194 | bayes_pls_golite062009 |
| exonuclease activity | 2.66053639652924 | bayes_pls_golite062009 |
| RNA binding | 2.41160981373213 | bayes_pls_golite062009 |
| ligase activity, forming aminoacyl-tRNA and related compounds | 2.04350689362549 | bayes_pls_golite062009 |
| ligase activity, forming carbon-oxygen bonds | 2.04350689362549 | bayes_pls_golite062009 |
| aminoacyl-tRNA ligase activity | 2.04218282227834 | bayes_pls_golite062009 |
| structural constituent of ribosome | 2.02605441840546 | bayes_pls_golite062009 |
| structure-specific DNA binding | 1.81524862921454 | bayes_pls_golite062009 |
| structural molecule activity | 1.81283970647925 | bayes_pls_golite062009 |
| single-stranded DNA binding | 1.62996999055328 | bayes_pls_golite062009 |
| 1.5765009871268 | bayes_pls_golite062009 | |
| exoribonuclease II activity | 1.18248519339188 | bayes_pls_golite062009 |
| telomeric DNA binding | 1.15591101342538 | bayes_pls_golite062009 |
| ligase activity | 1.06979791212194 | bayes_pls_golite062009 |
| transcription regulator activity | 0.996884322431837 | bayes_pls_golite062009 |
| hydrolase activity | 0.724860465280978 | bayes_pls_golite062009 |
| single-stranded telomeric DNA binding | 0.586976595520399 | bayes_pls_golite062009 |
| nuclease activity | 0.57381531077345 | bayes_pls_golite062009 |
| aspartate-tRNA ligase activity | 0.504302440847948 | bayes_pls_golite062009 |
| mRNA binding | 0.4162128308402 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 0.32084431704638 | bayes_pls_golite062009 |
| transcription factor activity | 0.298729064067577 | bayes_pls_golite062009 |
| translation regulator activity | 0.22908707234671 | bayes_pls_golite062009 |
| chromatin binding | 0.1876135725713 | bayes_pls_golite062009 |
| translation factor activity, nucleic acid binding | 0.179682348023561 | bayes_pls_golite062009 |
| protein binding | 0.152645195799531 | bayes_pls_golite062009 |
| translation initiation factor activity | 0.11625379846973 | bayes_pls_golite062009 |
| RNA polymerase activity | 0.0740938021136293 | bayes_pls_golite062009 |
| DNA-directed RNA polymerase activity | 0.0740938021136293 | bayes_pls_golite062009 |
|
Region A: Residues: [824-1001] |
1 11 21 31 41 51
| | | | | |
1 YSYPDFRHYG LAVDIYTHFT SPIRRYCDVV AHRQLAGAIG YEPLSLTHRD KNKMDMICRN 60
61 INRKHRNAQF AGRASIEYYV GQVMRNNEST ETGYVIKVFN NGIVVLVPKF GVEGLIRLDN 120
121 LTEDPNSAAF DEVEYKLTFV PTNSDKPRDV YVFDKVEVQV RSVMDPITSK RKAELLLK
|
| Detection Method: | |
| Confidence: | 14.39794 |
| Match: | 1go3E_ |
| Description: | C-terminal domain of RNA polymerase II subunit RBP4 (RpoE); N-terminal, heterodimerisation domain of RBP4 (RpoE) |
Matching Structure (courtesy of the PDB): |
|
