| Protein: | ACS2 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 683 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ACS2.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..683] | [1..683] |
|
|
0.0 | [22..672] | [6..644] |
|
|
0.0 | [22..672] | [6..644] |
|
|
0.0 | [22..672] | [6..644] |
|
|
0.0 | [18..670] | [2..639] |
|
|
0.0 | [22..672] | [6..644] |
|
|
0.0 | [22..672] | [6..644] |
|
|
0.0 | [1..673] | [6..663] |
|
|
0.0 | [1..683] | [1..675] |
|
|
0.0 | [19..671] | [3..644] |
|
Region A: Residues: [1-79] |
1 11 21 31 41 51
| | | | | |
1 MTIKEHKVVY EAHNVKALKA PQHFYNSQPG KGYVTDMQHY QEMYQQSINE PEKFFDKMAK 60
61 EYLHWDAPYT KVQSGSLNN
|
|
Region B: Residues: [345-531] |
1 11 21 31 41 51
| | | | | |
1 ESTPAYPDYG RYWRIIQRHK ATHFYVAPTA LRLIKRVGEA EIAKYDTSSL RVLGSVGEPI 60
61 SPDLWEWYHE KVGNKNCVIC DTMWQTESGS HLIAPLAGAV PTKPGSATVP FFGINACIID 120
121 PVTGVELEGN DVEGVLAVKS PWPSMARSVW NHHDRYMDTY LKPYPGHYFT GDGAGRDHDG 180
181 YYWIRGR
|
| Detection Method: |  |
| Confidence: | 269.218487 |
| Match: | 1amuA_ |
| Description: | Phenylalanine activating domain of gramicidin synthetase 1 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| ligase activity, forming carbon-sulfur bonds | 5.10123876514454 | bayes_pls_golite062009 |
| fatty acid ligase activity | 4.83067429373059 | bayes_pls_golite062009 |
| long-chain fatty acid-CoA ligase activity | 4.72692389032116 | bayes_pls_golite062009 |
| acetate-CoA ligase activity | 4.48129067128523 | bayes_pls_golite062009 |
| acid-thiol ligase activity | 4.28278725989432 | bayes_pls_golite062009 |
| CoA-ligase activity | 4.12850865352867 | bayes_pls_golite062009 |
| Photinus-luciferin 4-monooxygenase (ATP-hydrolyzing) activity | 2.74744781333102 | bayes_pls_golite062009 |
| oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) | 2.74744781333102 | bayes_pls_golite062009 |
| luciferin monooxygenase activity | 2.67396462766343 | bayes_pls_golite062009 |
| ligase activity | 2.49556073715112 | bayes_pls_golite062009 |
| transcription regulator activity | 2.31193176808353 | bayes_pls_golite062009 |
| catalytic activity | 1.83545185797733 | bayes_pls_golite062009 |
| binding | 1.5312519256537 | bayes_pls_golite062009 |
| transporter activity | 1.29780964436121 | bayes_pls_golite062009 |
| transcription repressor activity | 1.2638869228049 | bayes_pls_golite062009 |
| transmembrane transporter activity | 1.07143339827205 | bayes_pls_golite062009 |
| acetoacetate-CoA ligase activity | 1.03788694975627 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 1.03753946113449 | bayes_pls_golite062009 |
| protein binding | 0.985225190358794 | bayes_pls_golite062009 |
| AMP binding | 0.778227294974491 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 0.54797726647835 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 0.519946577969422 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 0.500908589473269 | bayes_pls_golite062009 |
| transferase activity, transferring acyl groups | 0.464663038956639 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 0.398310577427897 | bayes_pls_golite062009 |
| active transmembrane transporter activity | 0.251681382273558 | bayes_pls_golite062009 |
| primary active transmembrane transporter activity | 0.225448500718996 | bayes_pls_golite062009 |
| P-P-bond-hydrolysis-driven transmembrane transporter activity | 0.216579620878492 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances | 0.177812048124158 | bayes_pls_golite062009 |
| ATPase activity, coupled to movement of substances | 0.174283007890308 | bayes_pls_golite062009 |
| ATPase activity, coupled to transmembrane movement of substances | 0.173963339749644 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 0.0401881910649647 | bayes_pls_golite062009 |
| pyrophosphatase activity | 0.0047964784091391 | bayes_pls_golite062009 |
|
Region A: Residues: [80-127] |
1 11 21 31 41 51
| | | | | |
1 GDVAWFLNGK LNASYNCVDR HAFANPDKPA LIYEADDESD NKIITFGE
|
|
Region B: Residues: [280-344] |
1 11 21 31 41 51
| | | | | |
1 GSTGSPKGVV HTTGGYLLGA ALTTRYVFDI HPEDVLFTAG DVGWITGHTY ALYGPLTLGT 60
61 ASIIF
|
|
Region C: Residues: [532-683] |
1 11 21 31 41 51
| | | | | |
1 VDDVVNVSGH RLSTSEIEAS ISNHENVSEA AVVGIPDELT GQTVVAYVSL KDGYLQNNAT 60
61 EGDAEHITPD NLRRELILQV RGEIGPFASP KTIILVRDLP RTRSGKIMRR VLRKVASNEA 120
121 EQLGDLTTLA NPEVVPAIIS AVENQFFSQK KK
|
| Detection Method: | |
| Confidence: | 269.218487 |
| Match: | 1amuA_ |
| Description: | Phenylalanine activating domain of gramicidin synthetase 1 |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [128-279] |
1 11 21 31 41 51
| | | | | |
1 LLRKVSQIAG VLKSWGVKKG DTVAIYLPMI PEAVIAMLAV ARIGAIHSVV FAGFSAGSLK 60
61 DRVVDANSKV VITCDEGKRG GKTINTKKIV DEGLNGVDLV SRILVFQRTG TEGIPMKAGR 120
121 DYWWHEEAAK QRTYLPPVSC DAEDPLFLLY TS
|
| Detection Method: | |
| Confidence: | 269.218487 |
| Match: | 1amuA_ |
| Description: | Phenylalanine activating domain of gramicidin synthetase 1 |
| Matching Structure (courtesy of the PDB): |
|
