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View Structure Prediction Details

Protein: TDH2
Organism: Saccharomyces cerevisiae
Length: 332 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TDH2.

Description E-value Query
Range
Subject
Range
G3P_FELCA - Glyceraldehyde-3-phosphate dehydrogenase OS=Felis catus GN=GAPDH PE=2 SV=3
0.0 [1..330] [1..330]
G3P_CRIGR - Glyceraldehyde-3-phosphate dehydrogenase OS=Cricetulus griseus GN=GAPDH PE=2 SV=2
0.0 [1..330] [1..330]
GAPDH - glyceraldehyde-3-phosphate dehydrogenase
gi|55637711, gi|... - gi|55637711|ref|XP_508955.1| PREDICTED: glyceraldehyde-3-phosphate dehydrogenase isoform 5 [Pan trog...
gi|61362726, gi|... - gi|61362731|gb|AAX42271.1| glyceraldehyde-3-phosphate dehydrogenase [synthetic construct], gi|613627...
0.0 [2..330] [4..332]
G3P_RAT - Glyceraldehyde-3-phosphate dehydrogenase OS=Rattus norvegicus GN=Gapdh PE=1 SV=3
0.0 [1..330] [1..330]
G3P_MOUSE - Glyceraldehyde-3-phosphate dehydrogenase OS=Mus musculus GN=Gapdh PE=1 SV=2
0.0 [1..330] [1..330]
G3P_PIG - Glyceraldehyde-3-phosphate dehydrogenase OS=Sus scrofa GN=GAPDH PE=1 SV=4
0.0 [1..330] [1..330]
G3P_CANLF - Glyceraldehyde-3-phosphate dehydrogenase OS=Canis lupus familiaris GN=GAPDH PE=2 SV=3
0.0 [1..330] [1..330]
G3P_COTJA - Glyceraldehyde-3-phosphate dehydrogenase OS=Coturnix coturnix japonica GN=GAPDH PE=2 SV=2
gi|62616, gi|484434 - gi|62616|emb|CAA79512.1| glyceraldehydephosphate dehydrogenase [Coturnix coturnix], gi|484434|pir||J...
0.0 [1..330] [1..330]
G3P_RABIT - Glyceraldehyde-3-phosphate dehydrogenase - Oryctolagus cuniculus (Rabbit)
0.0 [1..330] [1..330]

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Predicted Domain #1
Region A:
Residues: [1-119]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVRVAINGFG RIGRLVMRIA LQRKNVEVVA LNDPFISNDY SAYMFKYDST HGRYAGEVSH  60
   61 DDKHIIVDGH KIATFQERDP ANLPWASLNI DIAIDSTGVF KELDTAQKHI DAGAKKVVI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1433.0
Match: 1crwG_
Description: Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
glyceraldehyde-3-phosphate dehydrogenase activity 6.40381118887682 bayes_pls_golite062009
glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity 5.96956214078036 bayes_pls_golite062009
oxidoreductase activity 4.00402564572912 bayes_pls_golite062009
1-deoxy-D-xylulose-5-phosphate reductoisomerase activity 3.16750187025282 bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors 2.70673476015931 bayes_pls_golite062009
catalytic activity 2.54843319568228 bayes_pls_golite062009
glucose-6-phosphate dehydrogenase activity 2.2713146106379 bayes_pls_golite062009
inositol-3-phosphate synthase activity 2.2178883592085 bayes_pls_golite062009
transcription regulator activity 1.90939908578582 bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 1.66955978224275 bayes_pls_golite062009
DNA binding 1.61355789916908 bayes_pls_golite062009
nucleic acid binding 1.48478425318425 bayes_pls_golite062009
hydrolase activity 1.40468563568607 bayes_pls_golite062009
binding 1.22114607236074 bayes_pls_golite062009
retinol dehydrogenase activity 1.16811519855038 bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors 1.11682034462164 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1.03017667696669 bayes_pls_golite062009
transcription factor activity 0.91090893050278 bayes_pls_golite062009
molecular transducer activity 0.910536752370264 bayes_pls_golite062009
signal transducer activity 0.910536752370264 bayes_pls_golite062009
alcohol dehydrogenase (NAD) activity 0.88293430762998 bayes_pls_golite062009
NAD or NADH binding 0.74536049628503 bayes_pls_golite062009
intramolecular lyase activity 0.708206800759221 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 0.527946013169731 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-CH group of donors 0.41382905800454 bayes_pls_golite062009
receptor activity 0.388215697182664 bayes_pls_golite062009
structural molecule activity 0.345975336806588 bayes_pls_golite062009
alcohol dehydrogenase activity, zinc-dependent 0.331048046502169 bayes_pls_golite062009
collagen binding 0.30621400535957 bayes_pls_golite062009
transmembrane receptor activity 0.211380641599388 bayes_pls_golite062009
NADPH:quinone reductase activity 0.136079082491021 bayes_pls_golite062009
glucose binding 0.13030486887358 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [120-148]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TAPSSTAPMF VMGVNEEKYT SDLKIVSNA

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [318-332]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YSTRVVDLVE HVAKA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1433.0
Match: 1crwG_
Description: Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [149-317]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SCTTNCLAPL AKVINDAFGI EEGLMTTVHS MTATQKTVDG PSHKDWRGGR TASGNIIPSS  60
   61 TGAAKAVGKV LPELQGKLTG MAFRVPTVDV SVVDLTVKLN KETTYDEIKK VVKAAAEGKL 120
  121 KGVLGYTEDA VVSSDFLGDS NSSIFDAAAG IQLSPKFVKL VSWYDNEYG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1433.0
Match: 1crwG_
Description: Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle