YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

The catalysis of certain rearrangements of a molecule to break or form a ring. Catalysis of the reaction: D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate; requires NAD, which dehydrogenates the CHOH group to CO at C-5 of the glucose 6-phosphate, making C-6 into an active methylene, able to condense with the aldehyde at C-1. Finally, the enzyme-bound NADH reconverts C-5 into the CHOH form. Catalysis of the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: inositol-3-phosphate synthase activity
Acc: GO:0004512
Aspect: Molecular Function
Desc: Catalysis of the reaction: D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate; requires NAD, which dehydrogenates the CHOH group to CO at C-5 of the glucose 6-phosphate, making C-6 into an active methylene, able to condense with the aldehyde at C-1. Finally, the enzyme-bound NADH reconverts C-5 into the CHOH form.
Synonyms:
  • 1L-myo-inositol-1-phosphate lyase (isomerizing)
  • inositol 1-phosphate synthetase activity
  • inositol 1-phosphate synthatase activity
  • myo-inositol-1-phosphate synthase activity
  • glucocycloaldolase activity
  • glucose 6-phosphate cyclase activity
  • glucose-6-phosphate inositol monophosphate cycloaldolase activity
  • D-glucose 6-phosphate cycloaldolase activity
Proteins in PDR annotated with:
   This term: 11 [Search]
   Term or descendants: 11 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004512 - inositol-3-phosphate synthase activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle