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View Structure Prediction Details

Protein: ECM14
Organism: Saccharomyces cerevisiae
Length: 430 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ECM14.

Description E-value Query
Range
Subject
Range
CBPB1_PIG - Carboxypeptidase B OS=Sus scrofa GN=CPB1 PE=1 SV=5
0.0 [9..426] [2..413]
CPB1 - carboxypeptidase B1 (tissue)
gi|123994061, gi... - gi|61359680|gb|AAX41752.1| carboxypeptidase B1 [synthetic construct], gi|61359674|gb|AAX41751.1| car...
0.0 [9..427] [2..414]
CBPA1_BOVIN - Carboxypeptidase A1 OS=Bos taurus GN=CPA1 PE=1 SV=3
0.0 [13..427] [4..416]
CBPB1_CANLF - Carboxypeptidase B OS=Canis lupus familiaris GN=CPB1 PE=2 SV=1
0.0 [11..427] [3..413]

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Predicted Domain #1
Region A:
Residues: [1-89]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLHMNSLWGC FLFVLLAVTG AVQGLQEDYS EYAVYRFTSD NYSTLVRDVI APLTDDYDVW  60
   61 TRSNNFIDIK LPKEIGEQIN DGQVIIDNM

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 583.0103
Match: 1aye__
Description: Carboxypeptidase A; Procarboxypeptidase A
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
peptidase activity 4.786910294594 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 4.40766568731738 bayes_pls_golite062009
hydrolase activity 4.23257784904124 bayes_pls_golite062009
exopeptidase activity 3.28577934113028 bayes_pls_golite062009
metallopeptidase activity 2.76103081380105 bayes_pls_golite062009
carboxypeptidase activity 2.63658263814587 bayes_pls_golite062009
metalloexopeptidase activity 1.76058821499096 bayes_pls_golite062009
metallocarboxypeptidase activity 1.56827526553175 bayes_pls_golite062009
catalytic activity 1.3989281287879 bayes_pls_golite062009
binding 1.18091528890016 bayes_pls_golite062009
endopeptidase activity 0.910234727191613 bayes_pls_golite062009
serine hydrolase activity 0.596149133958797 bayes_pls_golite062009
serine-type peptidase activity 0.578572340123331 bayes_pls_golite062009
nucleic acid binding 0.328807457631995 bayes_pls_golite062009
protein binding 0.215930537243465 bayes_pls_golite062009
aminopeptidase activity 0.0966237570696103 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [90-430]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NELIQNTLPT SQMMAREQAV FENDYDFFFN EYRDLDTIYM WLDLLERSFP SLVAVEHLGR  60
   61 TFEGRELKAL HISGNKPESN PEKKTIVITG GIHAREWISV STVCWALYQL LNRYGSSKKE 120
  121 TKYLDDLDFL VIPVFNPDGY AYTWSHDRLW RKNRQRTHVP QCLGIDIDHS FGFQWEKAHT 180
  181 HACSEEYSGE TPFEAWEASA WYKYINETKG DYKIYGYIDM HSYSQEILYP YAYSCDALPR 240
  241 DLENLLELSY GLSKAIRSKS GRNYDVISAC KDRGSDIFPG LGAGSALDFM YHHRAHWAFQ 300
  301 LKLRDTGNHG FLLPPENIKP VGKETYAALK YFCDFLLDPE I

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 583.0103
Match: 1aye__
Description: Carboxypeptidase A; Procarboxypeptidase A
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle