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View Structure Prediction Details

Protein: NDT80
Organism: Saccharomyces cerevisiae
Length: 627 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NDT80.

Description E-value Query
Range
Subject
Range
gi|1171680, gi|1... - gi|1171680|sp|P38830|NDT80_YEAST Protein NDT80, gi|1016717|gb|AAA92299.1| Ndt80p
0.0 [1..627] [1..627]
gi|16945421 - gi|16945421|emb|CAB91351.2| related to meiosis-specific protein NDT80 [Neurospora crassa]
gi|164429275, gi... - gi|164429275|ref|XP_958201.2| hypothetical protein NCU09915 [Neurospora crassa OR74A], gi|157073009|...
1.0E-76 [95..336] [109..313]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
2.0E-76 [95..336] [129..333]

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Predicted Domain #1
Region A:
Residues: [1-434]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNEMENTDPV LQDDLVSKYE RELSTEQEED TPVILTQLNE DGTTSNYFDK RKLKIAPRST  60
   61 LQFKVGPPFE LVRDYCPVVE SHTGRTLDLR IIPRIDRGFD HIDEEWVGYK RNYFTLVSTF 120
  121 ETANCDLDTF LKSSFDLLVE DSSVESRLRV QYFAIKIKAK NDDDDTEINL VQHTAKRDKG 180
  181 PQFCPSVCPL VPSPLPKHQI IREASNVRNI TKMKKYDSTF YLHRDHVNYE EYGVDSLLFS 240
  241 YPEDSIQKVA RYERVQFASS ISVKKPSQQN KHFSLHVILG AVVDPDTFHG ENPGIPYDEL 300
  301 ALKNGSKGMF VYLQEMKTPP LIIRGRSPSN YASSQRITVR TPSSVNSSQN STKRKMPSMA 360
  361 QPLNESCLNA RPSKRRSKVA LGAPNSGASI SPIKSRQSTP MEASKENEDP FFRPNKRVET 420
  421 LEHIQNKLGA LKNQ

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
transcription regulator activity 5.42929256050781 bayes_pls_golite062009
DNA binding 5.06641178315703 bayes_pls_golite062009
nucleic acid binding 4.74995074999042 bayes_pls_golite062009
binding 4.35229901672243 bayes_pls_golite062009
transcription factor activity 4.30059567378483 bayes_pls_golite062009
sequence-specific DNA binding 2.72947352424854 bayes_pls_golite062009
transcription activator activity 2.56828839945617 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.23604897773023 bayes_pls_golite062009
protein binding 1.90381218061757 bayes_pls_golite062009
transcription repressor activity 1.27337392672914 bayes_pls_golite062009
structure-specific DNA binding 1.18312413193055 bayes_pls_golite062009
double-stranded DNA binding 1.15539761996001 bayes_pls_golite062009
DNA strand annealing activity 0.952279913363481 bayes_pls_golite062009
single-stranded DNA binding 0.75467711075231 bayes_pls_golite062009
transcription factor binding 0.628837188707778 bayes_pls_golite062009
chromatin binding 0.4119609397091 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [435-627]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CPDSSLKYPS SSSRGMEGCL EKEDLVYSSS FSVNMKQIEL KPARSFEHEN IFKVGSLAFK  60
   61 KINELPHENY DITIEKKSME QNYLRPEIGS RSECKTSYGN ELSLSNISFS ILPNSAENFH 120
  121 LETALFPATE EDVPRTFSRI LETGSFQNYY QKMDAENADR VYSKGVKLIA SGTLPSGIFN 180
  181 REELFEEDSF YKY

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [524-627]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SRSECKTSYG NELSLSNISF SILPNSAENF HLETALFPAT EEDVPRTFSR ILETGSFQNY  60
   61 YQKMDAENAD RVYSKGVKLI ASGTLPSGIF NREELFEEDS FYKY

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle