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View Structure Prediction Details

Protein: RTG2
Organism: Saccharomyces cerevisiae
Length: 588 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RTG2.

Description E-value Query
Range
Subject
Range
gi|207345577 - gi|207345577|gb|EDZ72351.1| YGL252Cp-like protein [Saccharomyces cerevisiae AWRI1631]
gi|151943567 - gi|151943567|gb|EDN61877.1| sensor of mitochondrial dysfunction [Saccharomyces cerevisiae YJM789]
RTG2_YEAST - Retrograde regulation protein 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RTG2 PE=...
RTG2 - Sensor of mitochondrial dysfunction; regulates the subcellular location of Rtg1p and Rtg3p, transcri...
0.0 [1..588] [1..588]
gi|213864750 - gi|213864750|ref|ZP_03386869.1| exopolyphosphatase [Salmonella enterica subsp. enterica serovar Typh...
gi|213647473 - gi|213647473|ref|ZP_03377526.1| exopolyphosphatase [Salmonella enterica subsp. enterica serovar Typh...
gi|224582963, gi... - gi|224582963|ref|YP_002636761.1| exopolyphosphatase [Salmonella enterica subsp. enterica serovar Par...
gi|214002891 - gi|214002891|ref|ZP_03413626.1| exopolyphosphatase [Salmonella enterica subsp. enterica serovar Typh...
gi|194450339, gi... - gi|194450339|ref|YP_002046566.1| exopolyphosphatase [Salmonella enterica subsp. enterica serovar Hei...
gi|168466751, gi... - gi|195630753|gb|EDX49345.1| exopolyphosphatase [Salmonella enterica subsp. enterica serovar Newport ...
gi|213160884 - gi|213160884|ref|ZP_03346594.1| exopolyphosphatase [Salmonella enterica subsp. enterica serovar Typh...
gi|199604572, gi... - gi|200387474|ref|ZP_03214086.1| exopolyphosphatase [Salmonella enterica subsp. enterica serovar Virc...
gi|161362107, gi... - gi|161612743|ref|YP_001586708.1| exopolyphosphatase [Salmonella enterica subsp. enterica serovar Par...
PPX_SALTI - Exopolyphosphatase OS=Salmonella typhi GN=ppx PE=3 SV=2
PPX_SALTY - Exopolyphosphatase OS=Salmonella typhimurium GN=ppx PE=3 SV=2
PPX_SALTI - Exopolyphosphatase OS=Salmonella typhi GN=ppx PE=3 SV=2
gi|238913641 - gi|238913641|ref|ZP_04657478.1| exopolyphosphatase [Salmonella enterica subsp. enterica serovar Tenn...
gi|29140883, gi|... - gi|29140883|ref|NP_804225.1| exopolyphosphatase [Salmonella enterica subsp. enterica serovar Typhi s...
gi|16761420 - gi|16761420|ref|NP_457037.1| exopolyphosphatase [Salmonella enterica subsp. enterica serovar Typhi s...
lcl|NC_016856.1_... - [gene=ppx] [protein=exopolyphosphatase] [protein_id=YP_005238595.1] [location=2668560..2670101]
PPX_SALTY - Exopolyphosphatase OS=Salmonella typhimurium GN=ppx PE=3 SV=2
PPX_SALTY - Exopolyphosphatase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=ppx PE=3 SV=2
0.0 [8..476] [2..443]
gi|4760367 - gi|4760367|gb|AAD29107.1|AF053463_1 exopolyphosphatase; PPX [Pseudomonas aeruginosa]
gi|115588609, gi... - gi|53726702|ref|ZP_00347668.1| COG0248: Exopolyphosphatase [Pseudomonas aeruginosa UCBPP-PA14], gi|1...
0.0 [7..481] [5..452]
PPX_PSEAE - Exopolyphosphatase OS=Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228) G...
gi|107104343 - gi|107104343|ref|ZP_01368261.1| hypothetical protein PaerPA_01005418 [Pseudomonas aeruginosa PACS2]
gi|218894343, gi... - gi|218894343|ref|YP_002443213.1| exopolyphosphatase [Pseudomonas aeruginosa LESB58], gi|218774572|em...
gi|126197255, gi... - gi|84324055|ref|ZP_00972120.1| COG0248: Exopolyphosphatase [Pseudomonas aeruginosa 2192], gi|2542438...
gi|126169993, gi... - gi|84317890|ref|ZP_00966325.1| COG0248: Exopolyphosphatase [Pseudomonas aeruginosa C3719], gi|254238...
PPX_PSEAE - Exopolyphosphatase OS=Pseudomonas aeruginosa GN=ppx PE=3 SV=1
0.0 [7..481] [5..452]
gi|77629846, gi|... - gi|77629846|ref|ZP_00792432.1| COG0248: Exopolyphosphatase [Yersinia pseudotuberculosis IP 31758], g...
gi|165937131, gi... - gi|89104917|ref|ZP_01177447.1| COG0248: Exopolyphosphatase [Yersinia pestis biovar Orientalis str. I...
gi|165926016, gi... - gi|165926016|ref|ZP_02221848.1| exopolyphosphatase [Yersinia pestis biovar Orientalis str. F1991016]...
gi|165992796, gi... - gi|166008414|ref|ZP_02229312.1| exopolyphosphatase [Yersinia pestis biovar Antiqua str. E1979001], g...
gi|166206438, gi... - gi|166212507|ref|ZP_02238542.1| exopolyphosphatase [Yersinia pestis biovar Antiqua str. B42003004], ...
gi|166960759, gi... - gi|167421270|ref|ZP_02313023.1| exopolyphosphatase [Yersinia pestis biovar Orientalis str. MG05-1020...
gi|229681652, gi... - gi|229901723|ref|ZP_04516845.1| exopolyphosphatase [Yersinia pestis Nepal516], gi|229681652|gb|EEO77...
gi|167056354, gi... - gi|167424472|ref|ZP_02316225.1| exopolyphosphatase [Yersinia pestis biovar Mediaevalis str. K1973002...
Q668D7|Q668D7_YERPS - Putative exopolyphosphatase - Yersinia pseudotuberculosis
gi|167467165 - gi|167467165|ref|ZP_02331869.1| exopolyphosphatase [Yersinia pestis FV-1]
gi|149365300, gi... - gi|149365300|ref|ZP_01887335.1| exopolyphosphatase [Yersinia pestis CA88-4125], gi|149291713|gb|EDM4...
gi|169750119, gi... - gi|170023585|ref|YP_001720090.1| exopolyphosphatase [Yersinia pseudotuberculosis YPIII], gi|16975011...
gi|145599461, gi... - gi|145599461|ref|YP_001163537.1| exopolyphosphatase [Yersinia pestis Pestoides F], gi|145211157|gb|A...
gi|186896210, gi... - gi|186896210|ref|YP_001873322.1| exopolyphosphatase [Yersinia pseudotuberculosis PB1/+], gi|18669923...
gi|229694778, gi... - gi|229838412|ref|ZP_04458571.1| exopolyphosphatase [Yersinia pestis biovar Orientalis str. PEXU2], g...
gi|229701555, gi... - gi|229895400|ref|ZP_04510572.1| exopolyphosphatase [Yersinia pestis Pestoides A], gi|229701555|gb|EE...
gi|25290375 - pir||AF0345 probable exopolyphosphatase (EC 3.6.1.11) [imported] - Yersinia pestis (strain CO92)
gi|229898979, gi... - gi|229898979|ref|ZP_04514123.1| exopolyphosphatase [Yersinia pestis biovar Orientalis str. India 195...
gi|45437342, gi|... - gi|45442477|ref|NP_994016.1| exopolyphosphatase [Yersinia pestis biovar Microtus str. 91001], gi|454...
gi|22125295, gi|... - gi|22125295|ref|NP_668718.1| exopolyphosphatase [Yersinia pestis KIM], gi|21958171|gb|AAM84969.1|AE0...
gi|218929900, gi... - gi|218929900|ref|YP_002347775.1| exopolyphosphatase [Yersinia pestis CO92], gi|16123032|ref|NP_40634...
gi|51597119, gi|... - gi|51597119|ref|YP_071310.1| exopolyphosphatase [Yersinia pseudotuberculosis IP 32953], gi|51590401|...
0.0 [16..475] [11..443]
gi|15832618, gi|... - gi|15832618|ref|NP_311391.1| exopolyphosphatase [Escherichia coli O157:H7 str. Sakai], gi|13362834|d...
gi|89109308, gi|... - gi|89109308|ref|AP_003088.1| exopolyphosphatase [Escherichia coli str. K-12 substr. W3110], gi|18055...
gi|91211823, gi|... - gi|91211823|ref|YP_541809.1| exopolyphosphatase [Escherichia coli UTI89], gi|91073397|gb|ABE08278.1|...
PPX_ECOLI - Exopolyphosphatase (EC 3.6.1.11) (ExopolyPase) (Metaphosphatase) - Escherichia coli
PPX_ECOL6 - Exopolyphosphatase OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=ppx PE=3 SV=2
gi|188017022, gi... - gi|188017022|gb|EDU55144.1| exopolyphosphatase [Escherichia coli O157:H7 str. EC4113], gi|168748440|...
PPX_ECO57 - Exopolyphosphatase OS=Escherichia coli O157:H7 GN=ppx PE=1 SV=2
gi|168756273, gi... - gi|189356554|gb|EDU74973.1| exopolyphosphatase [Escherichia coli O157:H7 str. EC4401], gi|168756273|...
EG11403 - exopolyphosphatase / Exopolyphosphatase; inhibited by pppGpp and ppGpp, also has guanosine pentaphos...
gi|168773585, gi... - gi|187770642|gb|EDU34486.1| exopolyphosphatase [Escherichia coli O157:H7 str. EC4196], gi|168773585|...
gi|12516890, gi|... - gi|15803025|ref|NP_289055.1| exopolyphosphatase [Escherichia coli O157:H7 EDL933], gi|12516890|gb|AA...
gi|189003181, gi... - gi|189003181|gb|EDU72167.1| exopolyphosphatase [Escherichia coli O157:H7 str. EC4076], gi|168778467|...
gi|189372364, gi... - gi|189372364|gb|EDU90780.1| exopolyphosphatase [Escherichia coli O157:H7 str. EC869], gi|168787847|r...
gi|209398375, gi... - gi|209398375|ref|YP_002271971.1| exopolyphosphatase [Escherichia coli O157:H7 str. EC4115], gi|20915...
gi|209913238, gi... - gi|209919979|ref|YP_002294063.1| exopolyphosphatase [Escherichia coli SE11], gi|209913238|dbj|BAG783...
gi|217319566, gi... - gi|217327199|ref|ZP_03443282.1| exopolyphosphatase [Escherichia coli O157:H7 str. TW14588], gi|21731...
EG11403 - exopolyphosphatase / Exopolyphosphatase; inhibited by pppGpp and ppGpp, also has guanosine pentaphos...
gi|218559426, gi... - gi|218559426|ref|YP_002392339.1| exopolyphosphatase [Escherichia coli S88], gi|218366195|emb|CAR0394...
gi|218696129, gi... - gi|218696129|ref|YP_002403796.1| exopolyphosphatase [Escherichia coli 55989], gi|218352861|emb|CAU98...
gi|254794447, gi... - gi|254794447|ref|YP_003079284.1| exopolyphosphatase [Escherichia coli O157:H7 str. TW14359], gi|2545...
gi|218706001, gi... - gi|218706001|ref|YP_002413520.1| exopolyphosphatase [Escherichia coli UMN026], gi|218433098|emb|CAR1...
gi|253974377, gi... - gi|254162476|ref|YP_003045584.1| exopolyphosphatase [Escherichia coli B str. REL606], gi|253974377|g...
gi|253323650, gi... - gi|254289237|ref|YP_003054985.1| exopolyphosphatase [Escherichia coli BL21(DE3)], gi|253978544|gb|AC...
gi|251785827, gi... - gi|251785827|ref|YP_003000131.1| hypothetical protein B21_02356 [Escherichia coli BL21], gi|24237810...
gi|168798872, gi... - gi|189378553|gb|EDU96969.1| exopolyphosphatase [Escherichia coli O157:H7 str. EC508], gi|168798872|r...
gi|238861059, gi... - gi|238901667|ref|YP_002927463.1| exopolyphosphatase [Escherichia coli BW2952], gi|238861059|gb|ACR63...
gi|169754142, gi... - gi|170019214|ref|YP_001724168.1| exopolyphosphatase [Escherichia coli ATCC 8739], gi|169754142|gb|AC...
gi|226901374, gi... - gi|237705008|ref|ZP_04535489.1| exopolyphosphatase [Escherichia sp. 3_2_53FAA], gi|226901374|gb|EEH8...
gi|74313028, gi|... - gi|74313028|ref|YP_311447.1| exopolyphosphatase [Shigella sonnei Ss046], gi|73856505|gb|AAZ89212.1| ...
gi|169889947, gi... - gi|170082112|ref|YP_001731432.1| exopolyphosphatase [Escherichia coli str. K-12 substr. DH10B], gi|1...
gi|227835882, gi... - gi|227887532|ref|ZP_04005337.1| exopolyphosphatase [Escherichia coli 83972], gi|227835882|gb|EEJ4634...
PPX_ECOL6 - Exopolyphosphatase OS=Escherichia coli O6 GN=ppx PE=3 SV=2
gi|170682766, gi... - gi|170682766|ref|YP_001744686.1| exopolyphosphatase [Escherichia coli SMS-3-5], gi|170520484|gb|ACB1...
gi|195936644 - gi|195936644|ref|ZP_03082026.1| exopolyphosphatase [Escherichia coli O157:H7 str. EC4024]
gi|208728650, gi... - gi|208808849|ref|ZP_03251186.1| exopolyphosphatase [Escherichia coli O157:H7 str. EC4206], gi|208728...
gi|208814562, gi... - gi|208814562|ref|ZP_03255891.1| exopolyphosphatase [Escherichia coli O157:H7 str. EC4045], gi|208735...
gi|208739064, gi... - gi|208818941|ref|ZP_03259261.1| exopolyphosphatase [Escherichia coli O157:H7 str. EC4042], gi|208739...
gi|194423464, gi... - gi|83586849|ref|ZP_00925480.1| COG0248: Exopolyphosphatase [Escherichia coli 101-1], gi|194437658|re...
gi|193064767, gi... - gi|75257309|ref|ZP_00728833.1| COG0248: Exopolyphosphatase [Escherichia coli E22], gi|193064767|ref|...
gi|188493752, gi... - gi|75515843|ref|ZP_00737978.1| COG0248: Exopolyphosphatase [Escherichia coli 53638], gi|188493752|re...
gi|157078836, gi... - gi|75187254|ref|ZP_00700521.1| COG0248: Exopolyphosphatase [Escherichia coli E24377A], gi|157156806|...
gi|75211469, gi|... - gi|75211469|ref|ZP_00711559.1| COG0248: Exopolyphosphatase [Escherichia coli B171], gi|194427254|ref...
gi|117624686, gi... - gi|117624686|ref|YP_853599.1| exopolyphosphatase [Escherichia coli APEC O1], gi|115513810|gb|ABJ0188...
0.0 [13..476] [7..443]
gi|1805565 - dbj|BAA16392.1| exopolyphosphatase PPX [Escherichia coli]
0.0 [23..476] [1..427]
gi|3452466 - gi|3452466|gb|AAC32884.1| exopolyphosphatase [Vibrio cholerae]
0.0 [13..475] [5..440]
gi|229338951, gi... - gi|229525370|ref|ZP_04414775.1| exopolyphosphatase [Vibrio cholerae bv. albensis VL426], gi|22933895...
gi|229530145, gi... - gi|229530145|ref|ZP_04419535.1| exopolyphosphatase [Vibrio cholerae 12129(1)], gi|229333919|gb|EEN99...
gi|229350030, gi... - gi|229513137|ref|ZP_04402603.1| exopolyphosphatase [Vibrio cholerae TMA 21], gi|229350030|gb|EEO1498...
gi|229344503, gi... - gi|229517788|ref|ZP_04407232.1| exopolyphosphatase [Vibrio cholerae RC9], gi|229344503|gb|EEO09477.1...
gi|9655165, gi|1... - gi|9655165|gb|AAF93887.1| exopolyphosphatase [Vibrio cholerae O1 biovar El Tor str. N16961], gi|1564...
gi|11266438 - gi|11266438|pir||C82289 exopolyphosphatase VC0722 [imported] - Vibrio cholerae (strain N16961 serog...
gi|254285445, gi... - gi|254285445|ref|ZP_04960409.1| exopolyphosphatase [Vibrio cholerae AM-19226], gi|197752882|ref|YP_0...
gi|148875126, gi... - gi|153829406|ref|ZP_01982073.1| exopolyphosphatase [Vibrio cholerae 623-39], gi|148875126|gb|EDL7326...
gi|227080901, gi... - gi|227080901|ref|YP_002809452.1| exopolyphosphatase [Vibrio cholerae M66-2], gi|227008789|gb|ACP0500...
gi|229505662, gi... - gi|229505662|ref|ZP_04395172.1| exopolyphosphatase [Vibrio cholerae BX 330286], gi|229357885|gb|EEO2...
0.0 [13..475] [28..463]

Back

Predicted Domain #1
Region A:
Residues: [1-134]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTLSDSDTE TEVVSRNLCG IVDIGSNGIR FSISSKAAHH ARIMPCVFKD RVGLSLYEVQ  60
   61 YNTHTNAKCP IPRDIIKEVC SAMKRFKLIC DDFGVPETSV RVIATEATRD AINADEFVNA 120
  121 VYGSTGWKVE ILGQ

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 10.23
Match: 1jceA
Description: Prokaryotic actin homolog MreB
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
histone acetyltransferase activity 4.28232216932019 bayes_pls_golite062009
lysine N-acetyltransferase activity 4.28232216932019 bayes_pls_golite062009
N-acetyltransferase activity 2.69348633032984 bayes_pls_golite062009
N-acyltransferase activity 2.44825347420194 bayes_pls_golite062009
binding 2.11855816699924 bayes_pls_golite062009
acetyltransferase activity 2.07817518361957 bayes_pls_golite062009
protein binding 0.956664772028256 bayes_pls_golite062009
phosphoric ester hydrolase activity 0.746442016896597 bayes_pls_golite062009
kinase activity 0.745749848855807 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.712286564783673 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.63007037584851 bayes_pls_golite062009
phosphoric diester hydrolase activity 0.620856934459228 bayes_pls_golite062009
cytoskeletal protein binding 0.368147081469877 bayes_pls_golite062009
transcription regulator activity 0.309839091488096 bayes_pls_golite062009
catalytic activity 0.296484721581333 bayes_pls_golite062009
structural constituent of cytoskeleton 0.28741807440215 bayes_pls_golite062009
cyclic-nucleotide phosphodiesterase activity 0.177818098644499 bayes_pls_golite062009
nucleic acid binding 0.103902068310965 bayes_pls_golite062009
DNA binding 0.0569764181525874 bayes_pls_golite062009
3',5'-cyclic-nucleotide phosphodiesterase activity 0.0539674522232084 bayes_pls_golite062009
chromatin binding 0.0424425838189793 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [135-351]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EDETRVGIYG VVSSFNTVRG LYLDVAGGST QLSWVISSHG EVKQSSKPVS LPYGAGTLLR  60
   61 RMRTDDNRAL FYEIKEAYKD AIEKIGIPQE MIDDAKKEGG FDLWTRGGGL RGMGHLLLYQ 120
  121 SEGYPIQTII NGYACTYEEF SSMSDYLFLK QKIPGSSKEH KIFKVSDRRA LQLPAVGLFM 180
  181 SAVFEAIPQI KAVHFSEGGV REGSLYSLLP KEIRAQD

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 10.23
Match: 1jceA
Description: Prokaryotic actin homolog MreB
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [352-524]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLLIASRPYA PLLTEKYLYL LRTSIPQEDI PEIVNERIAP ALCNLAFVHA SYPKELQPTA  60
   61 ALHVATRGII AGCHGLSHRA RALIGIALCS RWGGNIPESE EKYSQELEQV VLREGDKAEA 120
  121 LRIVWWTKYI GTIMYVICGV HPGGNIRDNV FDFHVSKRSE VETSLKELII DDA

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [525-588]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NTTKVKEEST RKNRGYEVVV RISKDDLKTS ASVRSRIITL QKKVRKLSRG SVERVKIGVQ  60
   61 FYEE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle