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Protein Overview: PPX_ECOLI

General Information:
Name(s) found: PPX_ECOLI [Swiss-Prot]
Description(s) found:
Found 20 descriptions.
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  • Exopolyphosphatase (EC 3.6.1.11) (ExopolyPase) (Metaphosphatase) - Escherichia coli [Swiss-Prot]
    • Organism: Escherichia coli
    Length: 513 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPIHDKSPRP QEFAAVDLGS NSFHMVIARV VDGAMQIIGR LKQRVHLADG LGPDNMLSEE  60
   61 AMTRGLNCLS LFAERLQGFS PASVCIVGTH TLRQALNATD FLKRAEKVIP YPIEIISGNE 120
  121 EARLIFMGVE HTQPEKGRKL VIDIGGGSTE LVIGENFEPI LVESRRMGCV SFAQLYFPGG 180
  181 VINKENFQRA RMAAAQKLET LTWQFRIQGW NVAMGASGTI KAAHEVLMEM GEKDGIITPE 240
  241 RLEKLVKEVL RHRNFASLSL PGLSEERKTV FVPGLAILCG VFDALAIREL RLSDGALREG 300
  301 VLYEMEGRFR HQDVRSRTAS SLANQYHIDS EQARRVLDTT MQMYEQWREQ QPKLAHPQLE 360
  361 ALLRWAAMLH EVGLNINHSG LHRHSAYILQ NSDLPGFNQE QQLMMATLVR YHRKAIKLDD 420
  421 LPRFTLFKKK QFLPLIQLLR LGVLLNNQRQ ATTTPPTLTL ITDDSHWTLR FPHDWFSQNA 480
  481 LVLLDLEKEQ EYWEGVAGWR LKIEEESTPE IAA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..513] PSI-BLAST 136.0 Structure of an E. coli Exopolyphosphatase: Insight into the processive hydrolysis of polyphosphate and its regulation

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • kinase activity
    		•  1.87760960987608 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  1.75615325783105 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  1.59605394946105 bayes_pls_golite062009
  • binding
    		•  1.25460196265758 bayes_pls_golite062009
  • polyphosphate kinase activity
    		•  1.21204737821821 bayes_pls_golite062009
  • protein binding
    		•  1.01732312833155 bayes_pls_golite062009
  • phosphoric diester hydrolase activity
    		•  0.924155015104714 bayes_pls_golite062009
  • cyclic-nucleotide phosphodiesterase activity
    		•  0.641327801104871 bayes_pls_golite062009
  • transferase activity
    		•  0.569421514787167 bayes_pls_golite062009
  • 3',5'-cyclic-nucleotide phosphodiesterase activity
    		•  0.532800957697682 bayes_pls_golite062009
  • catalytic activity
    		•  0.296484721581333 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  0.232254847278069 bayes_pls_golite062009
  • ATP binding
    		•  0.20090931123533 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  0.164881755458122 bayes_pls_golite062009
  • protein kinase activity
    		•  0.0746500139691637 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.88

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle