| Protein: | PAN2 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 1115 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PAN2.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..1115] | [1..1115] |
|
|
0.0 | [33..1113] | [22..1094] |
|
|
0.0 | [21..456] | [833..1246] |
|
|
0.0 | [7..472] | [1051..1494] |
|
Region A: Residues: [1-395] |
1 11 21 31 41 51
| | | | | |
1 MNNWQHFFNN PVDLSEHLKK PYFRFDNRDK EITAISFDEK ANLIWSGDSY GCISSYDPTF 60
61 QLYTRYRGHI GGNSVKDILS HRDGILSISE DSLHFANRRG VTKLNLTSID IAAFSELNTM 120
121 CYSPHSLKNN IYCGGDNTNW GIASIDLNRG CLDSLLNYSS KVKLMCSNNK VLSIGRQTGT 180
181 VDLLDPTSNR TIKSFNAHSA SISAMDLRDN TLVTVGKSKR FYNLYADPFV NVYDLRTMRQ 240
241 LPPVSFSKGT TMGSGGADFV QLHPLLPTVM IVASSSGSFD FIDLSNPTLR TQYVHPCQSI 300
301 KKLCLSPNGD VLGILEADNH LDTWRRSSNN MGMFTNTPEM LAYPDYFNDI TSDGPISVDD 360
361 ETYPLSSVGM PYYLDKLLSA WPPVVFKSEG TIPQL
|
| Detection Method: |  |
| Confidence: | 75.522879 |
| Match: | 1gg2B_ |
| Description: | beta1-subunit of the signal-transducing G protein heterotrimer |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [396-468] |
1 11 21 31 41 51
| | | | | |
1 TGKSPLPSSG KLKSNLAVIS SQNEKLSTQE FPLLRYDRTK YGMRNAIPDY VCLRDIRKQI 60
61 TSGLETSDIQ TYT
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.710 | a.46.2 | Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain |
| View | Download | 0.676 | a.64.1 | Saposin |
| View | Download | 0.624 | a.23.5 | Hemolysin expression modulating protein HHA |
| View | Download | 0.656 | a.64.1 | Saposin |
| View | Download | 0.594 | a.28.2 | Colicin E immunity proteins |
| View | Download | 0.574 | a.4.1 | Homeodomain-like |
| View | Download | 0.530 | a.23.5 | Hemolysin expression modulating protein HHA |
| View | Download | 0.466 | a.51.1 | Cytochrome c oxidase subunit h |
| View | Download | 0.454 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.445 | a.144.1 | PABC (PABP) domain |
| View | Download | 0.418 | a.2.8 | Eukaryotic DNA topoisomerase I, dispensable insert domain |
| View | Download | 0.394 | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| View | Download | 0.392 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.388 | a.46.1 | Methionine synthase domain |
| View | Download | 0.372 | a.85.1 | Hemocyanin, N-terminal domain |
| View | Download | 0.354 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.352 | g.39.1 | Glucocorticoid receptor-like (DNA-binding domain) |
| View | Download | 0.350 | a.56.1 | CO dehydrogenase ISP C-domain like |
| View | Download | 0.349 | a.2.1 | GreA transcript cleavage protein, N-terminal domain |
| View | Download | 0.347 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.338 | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| View | Download | 0.338 | f.17.1 | F1F0 ATP synthase subunit C |
| View | Download | 0.335 | a.30.2 | Homodimeric domain of signal transducing histidine kinase |
| View | Download | 0.334 | a.35.1 | lambda repressor-like DNA-binding domains |
| View | Download | 0.332 | a.71.1 | Endoplasmic reticulum protein ERP29, C-domain |
| View | Download | 0.328 | g.53.1 | TAZ domain |
| View | Download | 0.318 | f.14.1 | Voltage-gated potassium channels |
| View | Download | 0.306 | a.156.1 | S13-like H2TH domain |
| View | Download | 0.306 | d.58.11 | EF-G/eEF-2 domains III and V |
| View | Download | 0.304 | a.2.7 | tRNA-binding arm |
| View | Download | 0.298 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.294 | a.2.1 | GreA transcript cleavage protein, N-terminal domain |
| View | Download | 0.287 | a.60.2 | RuvA domain 2-like |
| View | Download | 0.285 | d.68.6 | DNA-binding protein Sso10b (AlbA) |
| View | Download | 0.282 | a.4.1 | Homeodomain-like |
| View | Download | 0.278 | a.30.2 | Homodimeric domain of signal transducing histidine kinase |
| View | Download | 0.276 | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| View | Download | 0.251 | a.44.1 | Disulphide-bond formation facilitator (DSBA), insertion domain |
| View | Download | 0.248 | a.5.1 | DNA helicase RuvA subunit, C-terminal domain |
| View | Download | 0.240 | a.4.1 | Homeodomain-like |
| View | Download | 0.238 | a.4.1 | Homeodomain-like |
| View | Download | 0.238 | a.157.1 | Skp1 dimerisation domain-like |
| View | Download | 0.234 | a.7.7 | BAG domain |
| View | Download | 0.232 | a.30.2 | Homodimeric domain of signal transducing histidine kinase |
| View | Download | 0.231 | a.2.11 | Fe,Mn superoxide dismutase (SOD), N-terminal domain |
| View | Download | 0.229 | c.30.1 | PreATP-grasp domain |
| View | Download | 0.227 | g.53.1 | TAZ domain |
| View | Download | 0.225 | c.78.2 | Aspartate/glutamate racemase |
| View | Download | 0.223 | a.2.6 | Effector domain of the protein kinase pkn/prk1 |
| View | Download | 0.221 | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.218 | c.58.1 | Aminoacid dehydrogenase-like, N-terminal domain |
| View | Download | 0.218 | f.13.1 | Family A G protein-coupled receptor-like |
| View | Download | 0.217 | a.144.1 | PABC (PABP) domain |
| View | Download | 0.216 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.216 | g.57.1 | Serine proteinase inhibitor lekti |
| View | Download | 0.214 | a.60.9 | lambda integrase-like, N-terminal domain |
| View | Download | 0.210 | g.53.1 | TAZ domain |
| View | Download | 0.208 | a.2.11 | Fe,Mn superoxide dismutase (SOD), N-terminal domain |
| View | Download | 0.208 | d.169.1 | C-type lectin-like |
|
Region A: Residues: [469-895] |
1 11 21 31 41 51
| | | | | |
1 SINKYEVPPA YSRLPLTSGR FGTDNFDFTP FNNTEYSGLD PDVDNHYTNA IIQLYRFIPE 60
61 MFNFVVGCLK DENFETTLLT DLGYLFDMME RSHGKICSSS NFQASLKSLT DKRQLENGEP 120
121 QEHLEEYLES LCIRESIEDF NSSESIKRNM PQKFNRFLLS QLIKEEAQTV NHNITLNQCF 180
181 GLETEIRTEC SCDHYDTTVK LLPSLSISGI NKTVIKQLNK KSNGQNILPY IEYAMKNVTQ 240
241 KNSICPTCGK TETITQECTV KNLPSVLSLE LSLLDTEFSN IRSSKNWLTS EFYGSIIKNK 300
301 AVLRSTASEL KGTSHIFKYE LNGYVAKITD NNNETRLVTY VKKYNPKENC FKWLMFNDYL 360
361 VVEITEEEAL KMTYPWKTPE IIIYCDAEEL RKPFFSVDTY SINYDILFRD YFANGIRDTA 420
421 RREYKLL
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [896-1115] |
1 11 21 31 41 51
| | | | | |
1 THDEAPKSGT LVAIDAEFVS LQSELCEIDH QGIRSIIRPK RTALARISII RGEEGELYGV 60
61 PFVDDYVVNT NHIEDYLTRY SGILPGDLDP EKSTKRLVRR NVVYRKVWLL MQLGCVFVGH 120
121 GLNNDFKHIN INVPRNQIRD TAIYFLQGKR YLSLRYLAYV LLGMNIQEGN HDSIEDAHTA 180
181 LILYKKYLHL KEKAIFEKVL NSVYEEGRAH NFKVPETSKG
|
| Detection Method: | |
| Confidence: | 7.52 |
| Match: | 1fxxA |
| Description: | Exonuclease I |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| ribonuclease activity | 5.30591758406946 | bayes_pls_golite062009 |
| poly(A)-specific ribonuclease activity | 4.26301879074656 | bayes_pls_golite062009 |
| exoribonuclease activity | 3.71639182685131 | bayes_pls_golite062009 |
| exoribonuclease activity, producing 5'-phosphomonoesters | 3.59362615133405 | bayes_pls_golite062009 |
| exonuclease activity | 3.13676176369406 | bayes_pls_golite062009 |
| nuclease activity | 3.11657409772275 | bayes_pls_golite062009 |
| 3.10149405290966 | bayes_pls_golite062009 | |
| ribonuclease H activity | 2.91966688044755 | bayes_pls_golite062009 |
| hydrolase activity | 2.78602644579272 | bayes_pls_golite062009 |
| endonuclease activity | 2.63074055051349 | bayes_pls_golite062009 |
| endoribonuclease activity | 2.59247838057313 | bayes_pls_golite062009 |
| hydrolase activity, acting on ester bonds | 2.57498413015114 | bayes_pls_golite062009 |
| 3'-5'-exoribonuclease activity | 2.12039058720352 | bayes_pls_golite062009 |
| exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters | 1.94077739152313 | bayes_pls_golite062009 |
| deoxyribonuclease activity | 1.87431870698721 | bayes_pls_golite062009 |
| transcription regulator activity | 1.80414039971082 | bayes_pls_golite062009 |
| endoribonuclease activity, producing 5'-phosphomonoesters | 1.74431545836806 | bayes_pls_golite062009 |
| nucleic acid binding | 1.73824903971928 | bayes_pls_golite062009 |
| DNA polymerase activity | 1.64519652804477 | bayes_pls_golite062009 |
| endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters | 1.59628511603826 | bayes_pls_golite062009 |
| DNA-directed DNA polymerase activity | 1.54576601235316 | bayes_pls_golite062009 |
| DNA binding | 1.53383838980295 | bayes_pls_golite062009 |
| 3'-5' exonuclease activity | 1.44123900197846 | bayes_pls_golite062009 |
| RNA binding | 1.43996903907704 | bayes_pls_golite062009 |
| binding | 1.35497934205068 | bayes_pls_golite062009 |
| catalytic activity | 1.25233849524628 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 0.897788693142573 | bayes_pls_golite062009 |
| transcription factor activity | 0.893245368597729 | bayes_pls_golite062009 |
| exodeoxyribonuclease activity, producing 5'-phosphomonoesters | 0.782108781904855 | bayes_pls_golite062009 |
| exodeoxyribonuclease activity | 0.77421125364834 | bayes_pls_golite062009 |
| structure-specific DNA binding | 0.541658282566651 | bayes_pls_golite062009 |
| endodeoxyribonuclease activity | 0.48776342704945 | bayes_pls_golite062009 |
| single-stranded DNA binding | 0.206750180223289 | bayes_pls_golite062009 |
| protein binding | 0.035326007863533 | bayes_pls_golite062009 |
