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View Structure Prediction Details

Protein: MIG1
Organism: Saccharomyces cerevisiae
Length: 504 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MIG1.

Description E-value Query
Range
Subject
Range
ZNF287 - zinc finger protein 287
0.0 [2..382] [386..749]
Z287_MOUSE, ZN28... - Zinc finger protein 287 OS=Mus musculus GN=Znf287 PE=2 SV=1, (Q9EQB9) Zinc finger protein 287 (Zfp-2...
0.0 [2..382] [391..754]
ZN252_CANLF - Zinc finger protein 252 OS=Canis lupus familiaris GN=ZNF252 PE=2 SV=1
0.0 [2..386] [453..848]

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Predicted Domain #1
Region A:
Residues: [1-89]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQSPYPMTQV SNVDDGSLLK ESKSKSKVAA KSEAPRPHAC PICHRAFHRL EHQTRHMRIH  60
   61 TGEKPHACDF PGCVKRFSRS DELTRHRRI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 134.70927
Match: 1lu6A_
Description: No description for 1lu6A_ was found.

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.47951889934838 bayes_pls_golite062009
nucleic acid binding 4.35187767955595 bayes_pls_golite062009
DNA binding 4.31051339571017 bayes_pls_golite062009
transcription factor activity 3.28758716579796 bayes_pls_golite062009
transcription repressor activity 3.07956158665183 bayes_pls_golite062009
binding 2.99742524370422 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.96255357208943 bayes_pls_golite062009
transcription activator activity 1.97757778483124 bayes_pls_golite062009
chromatin binding 1.91511881662436 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 1.35857850481346 bayes_pls_golite062009
sequence-specific DNA binding 1.26862497534835 bayes_pls_golite062009
transcription factor binding 1.23738346570539 bayes_pls_golite062009
transcription corepressor activity 1.16887811832337 bayes_pls_golite062009
structure-specific DNA binding 1.16875264917476 bayes_pls_golite062009
protein binding 0.952480850696098 bayes_pls_golite062009
double-stranded DNA binding 0.885270755906501 bayes_pls_golite062009
transcription cofactor activity 0.627794176881836 bayes_pls_golite062009
catalytic activity 0.263007611601737 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [90-193]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HTNSHPRGKR GRKKKVVGSP INSASSSATS IPDLNTANFS PPLPQQHLSP LIPIAIAPKE  60
   61 NSSRSSTRKG RKTKFEIGES GGNDPYMVSS PKTMAKIPVS VKPP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 134.70927
Match: 1lu6A_
Description: No description for 1lu6A_ was found.

Predicted Domain #3
Region A:
Residues: [194-254]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSLALNNMNY QTSSASTALS SLSNSHSGSR LKLNALSSLQ MMTPIASSAP RTVFIDGPEQ  60
   61 K

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.854 0.146 specific RNA polymerase II transcription factor activity d.58.17 Metal-binding domain

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.70988788192472 bayes_pls_golite062009
nucleic acid binding 4.58713908116892 bayes_pls_golite062009
DNA binding 4.56219307357342 bayes_pls_golite062009
transcription factor activity 3.50954949535763 bayes_pls_golite062009
transcription repressor activity 3.27542149084008 bayes_pls_golite062009
RNA polymerase II transcription factor activity 3.22082323675675 bayes_pls_golite062009
binding 3.10743787485868 bayes_pls_golite062009
transcription activator activity 2.19952417915035 bayes_pls_golite062009
chromatin binding 2.18464662431232 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 1.63161912031789 bayes_pls_golite062009
sequence-specific DNA binding 1.42975942698743 bayes_pls_golite062009
transcription factor binding 1.39608963544799 bayes_pls_golite062009
transcription corepressor activity 1.34049786451995 bayes_pls_golite062009
structure-specific DNA binding 1.32402779550955 bayes_pls_golite062009
double-stranded DNA binding 1.06887513322119 bayes_pls_golite062009
protein binding 1.00484935878505 bayes_pls_golite062009
transcription cofactor activity 0.77874411480713 bayes_pls_golite062009
catalytic activity 0.245893663605433 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [255-433]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QLQQQQNSLS PRYSNTVILP RPRSLTDFQG LNNANPNNNG SLRAQTQSSV QLKRPSSVLS  60
   61 LNDLLVGQRN TNESDSDFTT GGEDEEDGLK DPSNSSIDNL EQDYLQEQSR KKSKTSTPTT 120
  121 MLSRSTSGTN LHTLGYVMNQ NHLHFSSSSP DFQKELNNRL LNVQQQQQEQ HTLLQSQNT

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [434-504]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SNQSQNQNQN QMMASSSSLS TTPLLLSPRV NMINTAISTQ QTPISQSDSQ VQELETLPPI  60
   61 RSLPLPFPHM D

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.248 0.933 specific RNA polymerase II transcription factor activity a.4.5 "Winged helix" DNA-binding domain


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle