






| Protein: | RSC8 | 
| Organism: | Saccharomyces cerevisiae | 
| Length: | 557 amino acids | 
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 | 
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RSC8.
| Description | E-value | Query Range | Subject Range | 
|  | 0.0 | [1..557] | [1..557] | 
|  | 0.0 | [66..488] | [4..451] | 
|  | 0.0 | [2..438] | [337..759] | 
|  | 7.0E-87 | [2..397] | [342..742] | 
|  | 2.0E-85 | [9..463] | [62..506] | 
|  | 2.0E-73 | [2..254] | [362..619] | 
| Region A: Residues: [1-177] |       1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDTEKDKDV PMVDSHEATE EPPTTSTNTP SFPHLAQEQA KEESATLGAE VAHKKINYEQ  60
   61 EAQKLEEKAL RFLAKQTHPV IIPSFASWFD ISKIHEIEKR SNPDFFNDSS RFKTPKAYKD 120
  121 TRNFIINTYR LSPYEYLTIT AVRRNVAMDV ASIVKIHAFL EKWGLINYQI DPRTKPS | 
Shown below are all of our structure predictions for this domain.
					Click here to view only most confident match.
				
				
					
Found no structure predictions for this domain.
| Region A: Residues: [178-247] |       1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LIGPSFTGHF QVVLDTPQGL KPFLPENVIK QEVEGGDGAE PQVKKEFPVN LTIKKNVYDS  60
   61 AQDFNALQDE  | 
Shown below are all of our de novo (Rosetta) predictions for this domain.
					Click here to view only most confident match.
				
					
| MCM Score | SCOP Match | SCOP Description | ||
| View | Download | 0.561 | a.65.1 | Annexin | 
| View | Download | 0.543 | a.179.1 | Replisome organizer (g39p helicase loader/inhibitor protein) | 
| View | Download | 0.503 | a.60.4 | DNA repair protein Rad51, N-terminal domain | 
| View | Download | 0.453 | a.4.12 | TrpR-like | 
| View | Download | 0.339 | a.4.1 | Homeodomain-like | 
| View | Download | 0.306 | a.4.5 | "Winged helix" DNA-binding domain | 
| View | Download | 0.291 | d.50.3 | PI-Pfui intein middle domain | 
| View | Download | 0.288 | a.50.1 | Anaphylotoxins (complement system) | 
| View | Download | 0.238 | a.163.1 | Crustacean CHH/MIH/GIH neurohormone | 
| View | Download | 0.232 | a.4.1 | Homeodomain-like | 
| View | Download | 0.223 | a.77.1 | DEATH domain | 
| View | Download | 0.211 | a.4.5 | "Winged helix" DNA-binding domain | 
| View | Download | 0.206 | a.100.1 | 6-phosphogluconate dehydrogenase C-terminal domain-like | 
| Region A: Residues: [248-304] |       1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SRNSRQIHKV YICHTCGNES INVRYHNLRA RDTNLCSRCF QEGHFGANFQ SSDFIRL | 
| Detection Method: |  | 
| Confidence: | 21.853872 | 
| Match: | PF00569 | 
| Description: | Zinc finger, ZZ type | 
Shown below are all of our structure predictions for this domain.
					Click here to view only most confident match.
				
				
					
Found no structure predictions for this domain.
| Term | Confidence | Notes | 
| binding | 2.78710909602478 | bayes_pls_golite062009 | 
| transcription regulator activity | 2.72498741013971 | bayes_pls_golite062009 | 
| small conjugating protein ligase activity | 2.40569731991064 | bayes_pls_golite062009 | 
| nucleic acid binding | 2.32387297115017 | bayes_pls_golite062009 | 
| ligase activity | 2.30828657077565 | bayes_pls_golite062009 | 
| ubiquitin-protein ligase activity | 2.29312770004164 | bayes_pls_golite062009 | 
| general RNA polymerase II transcription factor activity | 2.11206038007886 | bayes_pls_golite062009 | 
| DNA binding | 2.00904221080834 | bayes_pls_golite062009 | 
| protein binding | 1.5975811408548 | bayes_pls_golite062009 | 
| acid-amino acid ligase activity | 1.3853719864144 | bayes_pls_golite062009 | 
| transcription factor activity | 1.22579085356684 | bayes_pls_golite062009 | 
| transcription factor binding | 1.11842175076436 | bayes_pls_golite062009 | 
| RNA polymerase II transcription factor activity | 0.90321253993065 | bayes_pls_golite062009 | 
| transcription repressor activity | 0.350170315296021 | bayes_pls_golite062009 | 
| transcription coactivator activity | 0.255669498391574 | bayes_pls_golite062009 | 
| transcription cofactor activity | 0.233838999434784 | bayes_pls_golite062009 | 
| catalytic activity | 0.14112008370434 | bayes_pls_golite062009 | 
| transcription activator activity | 0.126093965701234 | bayes_pls_golite062009 | 
| ligase activity, forming carbon-nitrogen bonds | 0.024993043379745 | bayes_pls_golite062009 | 
| Region A: Residues: [305-358] |       1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ENNGNSVKKN WSDQEMLLLL EGIEMYEDQW EKIADHVGGH KRVEDCIEKF LSLP | 
| Detection Method: |  | 
| Confidence: | 2.30103 | 
| Match: | 1h8aC_ | 
| Description: | v-Myb | 
| Matching Structure (courtesy of the PDB):  | |
| Region A: Residues: [359-431] |       1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IEDNYIREVV GSTLNGKGGD SRDGSVSGSK LMECVNDAVQ TLLQGDDKLG KVSDKSREIS  60
   61 EKYIEESQAI IQE | 
| Detection Method: |  | 
| Confidence: | 7.0 | 
| Match: | 1dg3A_ | 
| Description: | Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain; Interferon-induced guanylate-binding protein 1 (GBP1), N-terminal domain | 
| Matching Structure (courtesy of the PDB):  | |
| Region A: Residues: [432-557] |       1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LVKLTMEKLE SKFTKLCDLE TQLEMEKLKY VKESEKMLND RLSLSKQILD LNKSLEELNV  60
   61 SKKLVLISEQ VDSGIQLVEK DQEGDDEDGN TATGHGVKRV GKEGEEVGEG DSIAKLQPQV 120
  121 YKPWSL | 
| Detection Method: |  | 
| Confidence: | 7.0 | 
| Match: | 1dg3A_ | 
| Description: | Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain; Interferon-induced guanylate-binding protein 1 (GBP1), N-terminal domain | 
| Matching Structure (courtesy of the PDB):  | |