| Protein: | DIN7 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 430 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DIN7.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..430] | [1..430] |
|
|
2.0E-86 | [1..390] | [1..379] |
|
|
1.0E-84 | [1..409] | [1..423] |
|
|
2.0E-83 | [1..409] | [1..423] |
|
|
5.0E-83 | [1..367] | [1..358] |
|
|
2.0E-82 | [1..367] | [1..358] |
|
|
2.0E-80 | [1..387] | [1..379] |
|
|
4.0E-80 | [1..373] | [1..361] |
|
Region A: Residues: [1-349] |
1 11 21 31 41 51
| | | | | |
1 MGIPGLLPQL KRIQKQVSLK KYMYQTLAID GYAWLHRASC ACAFELVMNK PTNKYLQFFI 60
61 KRLQLLKRLK IKPYIVFDGD SLFVKNHTET RRRKKRLENE MIAKKLWSAG NRYNAMEYFQ 120
121 KSVDITPEMA KCIIDYCKLH SIPYIVAPFE ADPQMVYLEK MGLIQGIISE DSDLLVFGCK 180
181 TLITKLNDQG KALEISKDDF SALPENFPLG ELSEQQFRNL VCLAGCDYTS GIWKVGVVTA 240
241 MKIVKRYSEM KDILIQIERT EKLCFSKAFK QQVEFANYAF QYQRVFCPLS NQITTLNNIP 300
301 KAVTNSHAEI IKIMKCIGSV VERGSGVRKD VINTKNIDHK VHEMIAKGE
|
| Detection Method: |  |
| Confidence: | 164.0103 |
| Match: | 1a76__ |
| Description: | Flap endonuclease-1 (Fen-1 nuclease) |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| flap endonuclease activity | 3.67578601858151 | bayes_pls_golite062009 |
| endodeoxyribonuclease activity | 3.29138075959109 | bayes_pls_golite062009 |
| deoxyribonuclease activity | 3.25110450559975 | bayes_pls_golite062009 |
| exonuclease activity | 3.08589196968812 | bayes_pls_golite062009 |
| 5'-3' exonuclease activity | 2.82147159438565 | bayes_pls_golite062009 |
| nuclease activity | 2.11339581411994 | bayes_pls_golite062009 |
| exodeoxyribonuclease activity | 2.0005433655378 | bayes_pls_golite062009 |
| exodeoxyribonuclease activity, producing 5'-phosphomonoesters | 1.9833086883205 | bayes_pls_golite062009 |
| exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters | 1.91303769651266 | bayes_pls_golite062009 |
| 5'-3' exodeoxyribonuclease activity | 1.87664153967776 | bayes_pls_golite062009 |
| double-stranded DNA specific exodeoxyribonuclease activity | 1.68933217523176 | bayes_pls_golite062009 |
| hydrolase activity, acting on ester bonds | 1.6357876066979 | bayes_pls_golite062009 |
| hydrolase activity | 1.55146225298048 | bayes_pls_golite062009 |
| 5'-flap endonuclease activity | 1.44561869581238 | bayes_pls_golite062009 |
| endonuclease activity | 1.40552749109921 | bayes_pls_golite062009 |
| catalytic activity | 1.37534898662234 | bayes_pls_golite062009 |
| single-stranded DNA specific exodeoxyribonuclease activity | 1.27080587821961 | bayes_pls_golite062009 |
| DNA binding | 1.0824699122398 | bayes_pls_golite062009 |
| binding | 1.04616076007281 | bayes_pls_golite062009 |
| nucleic acid binding | 1.03274122519509 | bayes_pls_golite062009 |
| damaged DNA binding | 0.98172679437643 | bayes_pls_golite062009 |
| single-stranded DNA specific 5'-3' exodeoxyribonuclease activity | 0.807459896574807 | bayes_pls_golite062009 |
| structure-specific DNA binding | 0.71603644615457 | bayes_pls_golite062009 |
| endodeoxyribonuclease activity, producing 5'-phosphomonoesters | 0.620251812982006 | bayes_pls_golite062009 |
| protein binding | 0.236485289446406 | bayes_pls_golite062009 |
|
Region A: Residues: [350-430] |
1 11 21 31 41 51
| | | | | |
1 LHPVDMASKL INRERKLKAR KLFKVGLLGG ESNSFNKKVE QPLVDTQDVL SERENSLDNK 60
61 NASSIYMTSP AAISGTVPSI F
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
