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View Structure Prediction Details

Protein: RBG1
Organism: Saccharomyces cerevisiae
Length: 369 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RBG1.

Description E-value Query
Range
Subject
Range
DRG3_ARATH - Developmentally-regulated G-protein 3 OS=Arabidopsis thaliana GN=DRG3 PE=1 SV=1
1.0E-95 [1..369] [1..368]
gi|194198741, gi... - gi|195569634|ref|XP_002102814.1| GD20106 [Drosophila simulans], gi|194198741|gb|EDX12317.1| GD20106 ...
gi|220949542, gi... - gi|220958466|gb|ACL91776.1| CG6195-PA [synthetic construct], gi|220949542|gb|ACL87314.1| CG6195-PA [...
gi|195353604, gi... - gi|195353604|ref|XP_002043294.1| GM26898 [Drosophila sechellia], gi|194127408|gb|EDW49451.1| GM26898...
CG6195-PA - This gene is referred to in FlyBase by the symbol Dmel\CG6195 (CG6195, FBgn0038723). It is a protein...
6.0E-93 [4..369] [3..363]
DRG2_MOUSE - Developmentally-regulated GTP-binding protein 2 OS=Mus musculus GN=Drg2 PE=1 SV=1
gi|149052834 - gi|149052834|gb|EDM04651.1| rCG32787 [Rattus norvegicus]
6.0E-93 [4..369] [3..364]
gi|114668863 - gi|114668863|ref|XP_001158504.1| PREDICTED: developmentally regulated GTP binding protein 2 isoform ...
DRG2 - developmentally regulated GTP binding protein 2
1.0E-92 [4..369] [3..364]
DRG1_XENLA - Developmentally-regulated GTP-binding protein 1 OS=Xenopus laevis GN=drg1 PE=2 SV=1
2.0E-92 [1..369] [1..367]

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Predicted Domain #1
Region A:
Residues: [1-268]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTTVEKIKA IEDEMARTQK NKATSFHLGQ LKAKLAKLRR ELLTSASSGS GGGAGIGFDV  60
   61 ARTGVASVGF VGFPSVGKST LLSKLTGTES EAAEYEFTTL VTVPGVIRYK GAKIQMLDLP 120
  121 GIIDGAKDGR GRGKQVIAVA RTCNLLFIIL DVNKPLHHKQ IIEKELEGVG IRLNKTPPDI 180
  181 LIKKKEKGGI SITNTVPLTH LGNDEIRAVM SEYRINSAEI AFRCDATVDD LIDVLEASSR 240
  241 RYMPAIYVLN KIDSLSIEEL ELLYRIPN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 33.69897
Match: 1egaA_
Description: GTPase Era, N-terminal domain; GTPase Era C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [269-369]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AVPISSGQDW NLDELLQVMW DRLNLVRIYT KPKGQIPDFT DPVVLRSDRC SVKDFCNQIH  60
   61 KSLVDDFRNA LVYGSSVKHQ PQYVGLSHIL EDEDVVTILK K

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.559 0.018 cytoplasm d.58.7 RNA-binding domain, RBD
View Download 0.512 0.014 cytoplasm a.40.1 Calponin-homology domain, CH-domain
View Download 0.575 0.006 GTP binding d.58.5 GlnB-like
View Download 0.511 N/A N/A a.6.1 Putative DNA-binding domain
View Download 0.485 N/A N/A c.53.1 Resolvase-like
View Download 0.462 N/A N/A d.58.3 Protease propeptides/inhibitors
View Download 0.461 N/A N/A d.58.18 Regulatory domain in the aminoacid metabolism
View Download 0.444 N/A N/A d.68.4 YhbY-like
View Download 0.435 N/A N/A d.58.7 RNA-binding domain, RBD
View Download 0.432 N/A N/A d.58.18 Regulatory domain in the aminoacid metabolism
View Download 0.431 N/A N/A d.95.2 Homing endonucleases
View Download 0.426 N/A N/A d.58.7 RNA-binding domain, RBD
View Download 0.423 N/A N/A a.4.3 ARID-like
View Download 0.418 N/A N/A d.58.44 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
View Download 0.414 N/A N/A a.74.1 Cyclin-like
View Download 0.413 N/A N/A d.58.8 Viral DNA-binding domain
View Download 0.401 N/A N/A d.58.44 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
View Download 0.401 N/A N/A d.58.7 RNA-binding domain, RBD
View Download 0.397 N/A N/A d.58.11 EF-G/eEF-2 domains III and V
View Download 0.394 N/A N/A c.37.1 P-loop containing nucleoside triphosphate hydrolases
View Download 0.393 N/A N/A c.53.1 Resolvase-like
View Download 0.386 N/A N/A a.6.1 Putative DNA-binding domain
View Download 0.378 N/A N/A d.58.44 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
View Download 0.378 N/A N/A d.58.7 RNA-binding domain, RBD
View Download 0.376 N/A N/A d.58.44 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
View Download 0.370 N/A N/A d.58.17 Metal-binding domain
View Download 0.367 N/A N/A d.58.3 Protease propeptides/inhibitors
View Download 0.365 N/A N/A d.58.43 Mechanosensitive channel protein MscS (YggB), C-terminal domain
View Download 0.358 N/A N/A b.71.1 Glycosyl hydrolase domain
View Download 0.355 N/A N/A c.23.1 CheY-like
View Download 0.353 N/A N/A d.58.12 eEF-1beta-like
View Download 0.353 N/A N/A a.28.1 ACP-like
View Download 0.350 N/A N/A c.47.2 RNA 3'-terminal phosphate cyclase, RPTC, insert domain
View Download 0.346 N/A N/A d.58.18 Regulatory domain in the aminoacid metabolism
View Download 0.345 N/A N/A d.58.17 Metal-binding domain
View Download 0.344 N/A N/A c.55.5 MTH1175-like
View Download 0.341 N/A N/A c.15.1 BRCT domain
View Download 0.339 N/A N/A a.77.1 DEATH domain
View Download 0.338 N/A N/A a.158.1 F-box domain
View Download 0.338 N/A N/A d.58.10 Acylphosphatase-like
View Download 0.338 N/A N/A c.53.1 Resolvase-like
View Download 0.337 N/A N/A a.40.1 Calponin-homology domain, CH-domain
View Download 0.329 N/A N/A d.58.7 RNA-binding domain, RBD
View Download 0.325 N/A N/A d.58.13 Anticodon-binding domain of PheRS
View Download 0.319 N/A N/A d.58.18 Regulatory domain in the aminoacid metabolism
View Download 0.314 N/A N/A d.16.1 FAD-linked reductases, C-terminal domain
View Download 0.310 N/A N/A a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.308 N/A N/A c.53.1 Resolvase-like
View Download 0.306 N/A N/A c.53.1 Resolvase-like
View Download 0.304 N/A N/A d.75.2 DNA repair protein MutS, domain I
View Download 0.302 N/A N/A c.55.4 Translational machinery components
View Download 0.299 N/A N/A d.75.2 DNA repair protein MutS, domain I
View Download 0.297 N/A N/A d.52.3 Prokaryotic type KH domain (KH-domain type II)
View Download 0.296 N/A N/A d.75.2 DNA repair protein MutS, domain I
View Download 0.295 N/A N/A d.109.1 Actin depolymerizing proteins
View Download 0.293 N/A N/A c.30.1 PreATP-grasp domain
View Download 0.291 N/A N/A d.15.1 Ubiquitin-like
View Download 0.288 N/A N/A a.60.11 Hypothetical protein YjbJ
View Download 0.287 N/A N/A d.58.47 Hypothetical protein VC0424
View Download 0.286 N/A N/A d.15.1 Ubiquitin-like
View Download 0.285 N/A N/A a.60.11 Hypothetical protein YjbJ
View Download 0.279 N/A N/A c.53.1 Resolvase-like
View Download 0.277 N/A N/A d.58.7 RNA-binding domain, RBD
View Download 0.276 N/A N/A d.58.17 Metal-binding domain
View Download 0.273 N/A N/A d.58.12 eEF-1beta-like
View Download 0.272 N/A N/A d.39.1 Dynein light chain 8 (DLC8)
View Download 0.270 N/A N/A c.54.1 IIA domain of mannose transporter, IIA-Man
View Download 0.262 N/A N/A c.102.1 Cell-division inhibitor MinC, N-terminal domain
View Download 0.259 N/A N/A c.31.1 DHS-like NAD/FAD-binding domain
View Download 0.258 N/A N/A d.95.2 Homing endonucleases
View Download 0.256 N/A N/A d.16.1 FAD-linked reductases, C-terminal domain
View Download 0.256 N/A N/A c.23.6 Cobalamin (vitamin B12)-binding domain
View Download 0.255 N/A N/A d.236.1 DNA-binding protein Tfx
View Download 0.254 N/A N/A c.61.1 PRTase-like
View Download 0.250 N/A N/A d.89.1 Origin of replication-binding domain, RBD-like
View Download 0.248 N/A N/A d.74.3 RBP11-like subunits of RNA polymerase
View Download 0.247 N/A N/A d.58.12 eEF-1beta-like
View Download 0.246 N/A N/A d.58.12 eEF-1beta-like
View Download 0.244 N/A N/A d.39.1 Dynein light chain 8 (DLC8)
View Download 0.243 N/A N/A d.58.18 Regulatory domain in the aminoacid metabolism
View Download 0.242 N/A N/A c.23.6 Cobalamin (vitamin B12)-binding domain
View Download 0.239 N/A N/A c.95.1 Thiolase-like
View Download 0.239 N/A N/A c.2.1 NAD(P)-binding Rossmann-fold domains
View Download 0.238 N/A N/A d.58.4 Dimeric alpha+beta barrel
View Download 0.238 N/A N/A d.58.17 Metal-binding domain
View Download 0.235 N/A N/A c.26.2 Adenine nucleotide alpha hydrolases-like
View Download 0.229 N/A N/A d.129.4 Cell-division protein ZipA, C-terminal domain
View Download 0.229 N/A N/A b.1.18 E set domains
View Download 0.229 N/A N/A d.58.18 Regulatory domain in the aminoacid metabolism
View Download 0.222 N/A N/A d.58.27 Translational regulator protein regA
View Download 0.219 N/A N/A c.2.1 NAD(P)-binding Rossmann-fold domains
View Download 0.219 N/A N/A c.58.1 Aminoacid dehydrogenase-like, N-terminal domain
View Download 0.218 N/A N/A d.88.1 SRF-like
View Download 0.216 N/A N/A d.58.18 Regulatory domain in the aminoacid metabolism
View Download 0.216 N/A N/A d.50.3 PI-Pfui intein middle domain
View Download 0.214 N/A N/A c.2.1 NAD(P)-binding Rossmann-fold domains
View Download 0.210 N/A N/A a.60.9 lambda integrase-like, N-terminal domain
View Download 0.209 N/A N/A d.15.1 Ubiquitin-like
View Download 0.208 N/A N/A d.81.1 Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain
View Download 0.206 N/A N/A a.60.11 Hypothetical protein YjbJ
View Download 0.205 N/A N/A d.129.4 Cell-division protein ZipA, C-terminal domain
View Download 0.201 N/A N/A c.23.4 Succinyl-CoA synthetase domains
View Download 0.201 N/A N/A c.58.1 Aminoacid dehydrogenase-like, N-terminal domain

Predicted functions:

Term Confidence Notes
binding 2.64537357529343 bayes_pls_golite062009
nucleic acid binding 2.09956015274464 bayes_pls_golite062009
transcription regulator activity 2.09345198747025 bayes_pls_golite062009
guanyl nucleotide binding 1.89320355239381 bayes_pls_golite062009
guanyl ribonucleotide binding 1.88721318481223 bayes_pls_golite062009
GTP binding 1.87900088157196 bayes_pls_golite062009
DNA binding 1.87765278833074 bayes_pls_golite062009
GTPase activity 1.23010905798386 bayes_pls_golite062009
purine ribonucleotide binding 1.21658213854831 bayes_pls_golite062009
ribonucleotide binding 1.21652144153182 bayes_pls_golite062009
purine nucleotide binding 1.21571071905795 bayes_pls_golite062009
nucleotide binding 1.20347573865566 bayes_pls_golite062009
catalytic activity 1.00104173493322 bayes_pls_golite062009
motor activity 0.926612891775441 bayes_pls_golite062009
transcription factor activity 0.682439846757997 bayes_pls_golite062009
cytoskeletal protein binding 0.498311726132348 bayes_pls_golite062009
pyrophosphatase activity 0.219555040684154 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.198256709027213 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.197994873032963 bayes_pls_golite062009
protein binding 0.170837278876362 bayes_pls_golite062009
structural constituent of ribosome 0.089234257580272 bayes_pls_golite062009
helicase activity 0.0775311459068899 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle