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View Structure Prediction Details

Protein: EAF_SCHPO
Organism: Schizosaccharomyces pombe 972h-
Length: 985 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for EAF_SCHPO.

Description E-value Query
Range
Subject
Range
VID21_GIBZE - Chromatin modification-related protein VID21 OS=Gibberella zeae GN=VID21 PE=3 SV=1
AEF1_GIBZE - Chromatin modification-related protein EAF1 OS=Gibberella zeae (strain PH-1 / ATCC MYA-4620 / FGSC 9...
396.0 [0..3] [903..223]
VID21_EMENI, EAF... - Chromatin modification-related protein vid21 OS=Emericella nidulans GN=vid21 PE=3 SV=1, Chromatin mo...
EAF1_EMENI - Chromatin modification-related protein eaf1 OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CB...
392.0 [0..16] [950..102]
EAF1_NEUCR - Chromatin modification-related protein eaf-1 OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / ...
VID21_NEUCR - Chromatin modification-related protein vid-21 OS=Neurospora crassa GN=vid-21 PE=3 SV=1
360.0 [0..31] [912..234]
gi|145016150, gi... - gi|39977063|ref|XP_369919.1| hypothetical protein MGG_06434 [Magnaporthe grisea 70-15], gb|EAA56463....
358.0 [0..1] [901..161]
EAF1 - Component of the NuA4 histone acetyltransferase complex; acts as a platform for assembly of NuA4 sub...
346.0 [0..309] [892..188]
VID21_ASHGO - Chromatin modification-related protein VID21 OS=Ashbya gossypii GN=VID21 PE=3 SV=1
EAF1_ASHGO - Chromatin modification-related protein EAF1 OS=Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGS...
328.0 [0..220] [898..89]
gi|88181473, gi|... - gi|88181473|gb|EAQ88941.1| hypothetical protein CHGG_05560 [Chaetomium globosum CBS 148.51], gi|1161...
310.0 [0..33] [905..184]
gi|115398067, gi... - gi|115398067|ref|XP_001214625.1| conserved hypothetical protein [Aspergillus terreus NIH2624], gi|11...
308.0 [0..21] [942..141]
gi|159125016 - gi|159125016|gb|EDP50133.1| MYB and HSA domain protein [Aspergillus fumigatus A1163]
EAF1_ASPFU - Chromatin modification-related protein eaf1 OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / ...
VID21_ASPFU - Chromatin modification-related protein vid21 OS=Aspergillus fumigatus GN=vid21 PE=3 SV=1
292.0 [0..36] [961..152]

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Predicted Domain #1
Region A:
Residues: [1-88]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKQKETKTSQ IALVDGEKLS ITDSFASLFT LDEEEENDSV DNEEIKLTKE KHEKLLLLFW  60
   61 LHCKFPNGLE WLHSSSDLLP EQVSEWFN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [89-342]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FYQKYRFKRE SVTPIVEEPI VPEEPDNLEG VSEETPLKET SLELSEEEII TSKSPIPSPE  60
   61 TIHKNIDVEE KETIEPTTPV KEVETTAHAE EEKGPLTPDS EYAARQLTEE LANKSSQEEG 120
  121 VDKQLRVVEA TEKEHEEDGN EENVTVTKPV EVATDQVESK EVKKKEVSET TEPTAPPVTV 180
  181 AEVLEIEDKV PKVDEVEEVH SPEAKVTEND VENVQSGIDI EKTIQLLNNQ EIPSEQQIIS 240
  241 VDKATESPVQ EVAV

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [343-462]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DVNEKPVDEI VEPSKLQMEN KLPSEKSPTI DRTGVEAPLF ELSVSMPLTL IPPSKFSEPV  60
   61 KPELSSEAWL LRTEMSPLHL RLKNAHKYVL SDNWSHAYRE EIVRQSLHHL TVAKEKGIWS 120
  121 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [463-609]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FRQPKRQNEM PRLKTHRDYV LDEMQWMSID FSQERKWKII LAHRMANWVM DYHQASDKCT  60
   61 VCTPASLSKN KKPYMQENEH QKDSHEETFN EQIVSHFNLN DNNNNKVLSI PRDSLQFYNA 120
  121 VFSDDIFVTT NSEQIQNCVL NVPMYGP

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 34.107905
Match: PF07529.4
Description: No description for PF07529.4 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [610-679]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PTENNEYCEE ISEKYPITPV SRFAYAKTKL KSTCAKASRK RLFNQLELSP PESFMEKKAR  60
   61 SDENQLDGNK 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [680-812]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IKDDNQKLSS VGTFSVRPPY PPSSKDIRPE APWLPEEDEL LLLLLRRYSF NWEFVASRLT  60
   61 PPGLYIPLAE KRTAWDCFER WIQVDPRAAN VQLTGSHARL AQQKLDESLR HSDKVSQHLS 120
  121 LRDEGTPNHL IKH

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.54
Match: 1x58A
Description: Solution structures of the myb-like DNA binding domain of 4930532D21Rik protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
histone acetyltransferase activity 5.78270240334849 bayes_pls_golite062009
lysine N-acetyltransferase activity 5.78270240334849 bayes_pls_golite062009
N-acyltransferase activity 4.53404381270892 bayes_pls_golite062009
N-acetyltransferase activity 4.38345537045529 bayes_pls_golite062009
acetyltransferase activity 3.81897719505269 bayes_pls_golite062009
acyltransferase activity 3.35931919126926 bayes_pls_golite062009
transferase activity, transferring acyl groups other than amino-acyl groups 3.31384699789032 bayes_pls_golite062009
transferase activity, transferring acyl groups 3.09869056563841 bayes_pls_golite062009
transcription regulator activity 3.05971315776284 bayes_pls_golite062009
DNA binding 2.98143466641891 bayes_pls_golite062009
nucleic acid binding 2.85666780317594 bayes_pls_golite062009
binding 2.77786931095369 bayes_pls_golite062009
transcription factor activity 2.3234819540139 bayes_pls_golite062009
chromatin binding 1.46306211220814 bayes_pls_golite062009
sequence-specific DNA binding 1.23729321119532 bayes_pls_golite062009
protein deacetylase activity 1.23476914879396 bayes_pls_golite062009
histone deacetylase activity 1.18710646783152 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.02200659886159 bayes_pls_golite062009
protein binding 1.00288283679871 bayes_pls_golite062009
transcription repressor activity 0.700409976805769 bayes_pls_golite062009
transcription activator activity 0.58607600202198 bayes_pls_golite062009
structure-specific DNA binding 0.559482273209868 bayes_pls_golite062009
deacetylase activity 0.534082291544628 bayes_pls_golite062009
histone binding 0.489784140732052 bayes_pls_golite062009
transcription factor binding 0.270053518126008 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.151335943405565 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.142552446933995 bayes_pls_golite062009
double-stranded DNA binding 0.0110175210304684 bayes_pls_golite062009

Predicted Domain #7
Region A:
Residues: [813-985]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NSYFLLPTVS RHYRPITIFE AIRKILKKRE FAKKPTMTKR AIAPSAASTE KLPPVPSPLE  60
   61 LSRLKSEREA QIQQIQAQRN FAQLQSQNRA LRPQNAAVAA GAQQHNQQLA AFQAVAASQN 120
  121 SSNNSSAGVS PIAGRMVPRL QPYAVSSSLK LTPEQIHQLQ QRKQTVPTTE RTQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle