| Protein: | Ih-PE |
| Organism: | Drosophila melanogaster |
| Length: | 1327 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Ih-PE.
| Description | E-value | Query Range |
Subject Range |
|
|
1006.0 | [0..1] | [1327..1] |
|
Region A: Residues: [1-115] |
1 11 21 31 41 51
| | | | | |
1 MHVKHTQRRV SGPGAFGTFT NDQRASRDNL CPDNQQQQQQ RHSHSHQHLV RQSLVSLSNG 60
61 QPAASAAPDS VSLLRAGDDQ QQHPQQPHLQ QQQQQQQHLQ QQQQRHRSSS SRLST
|
| Detection Method: |  |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [116-336] |
1 11 21 31 41 51
| | | | | |
1 SGISKQNSSD SRSGLRILDS SHSPVSCGTQ SVSSTGGQSA LYDACHEYSR SLSAAAAEGA 60
61 ASLLKSHYSD QQLAQTEPDP EPDPERDRDR DRDRDRDRER ERRHLTNLNL NLSSEYDYSG 120
121 SDKQQLVNET YIFKCIANSP SFLRTNKIKE QSKKLRNLSL KTRTAKKKGQ IISKSNAVSD 180
181 NSLHPGDKYL NLYLVEKKHS LQPQVASTSS SINTTHPQAS S
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [337-465] |
1 11 21 31 41 51
| | | | | |
1 APASSSSTCT KAPQLPALSA VAARQQQLLL NGSLKGKGQS QSQGQSRQTL PGHRASVRSE 60
61 SGSGSSHTIP ATGKSPPVPH SLAAKISSSA SGSKNCNLLS ASSNSCHKLN AHAQGSGAGS 120
121 GSGSGSGSG
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [466-518] |
1 11 21 31 41 51
| | | | | |
1 PPGHSHYAAA SPKSSVSSNG HLNKYCLTDL TRRKAEFNRQ LSAPTDYTHH SSS
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [519-595] |
1 11 21 31 41 51
| | | | | |
1 NGSQQEGSSE ANEGHEPVGE STITVASAGV SYPHPYSYPY HYAHHASSAT APANLKASLQ 60
61 LHSFGSHHPC PYPARPT
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [596-1015] |
1 11 21 31 41 51
| | | | | |
1 STSCTNSFNR RHIRRHKGKL GDRLLSGDSE ESVRCSYCSV LNVNDNDLRI SFENTCTDSL 60
61 VTAFDDEALL ICDQGTEMVH FDDVSLYGTP KEEPMPNIPI VSEKVSANFL KSQLQSWFQP 120
121 TDNRLAMKLF GSRKALVKER IRQKTSGHWV IHPCSSFRFY WDLCMLLLLV ANLIILPVAI 180
181 SFFNDDLSTR WIAFNCLSDT IFLIDIVVNF RTGIMQQDNA EQVILDPKLI AKHYLRTWFF 240
241 LDLISSIPLD YIFLIFNQIM KLQDFSDSFQ ILHAGRALRI LRLAKLLSLV RLLRLSRLVR 300
301 YVSQWEEVYI LQNLQKKSAD RRGRMNRKDK DGLTKSNLIL KFLNMASVFM RIFNLICMML 360
361 LIGHWSGCLQ FLVPMLQGFP SNSWVSINEL QESYWLEQYS WALFKAMSHM LCIGYGRFPP 420
421
|
| Detection Method: | |
| Confidence: | 4.39794 |
| Match: | 2nyyA |
| Description: | No description for 2nyyA was found. |
| Term | Confidence | Notes |
| amine binding | 1.56690065078434 | bayes_pls_golite062009 |
| binding | 1.31086473286665 | bayes_pls_golite062009 |
| transporter activity | 0.883938295782649 | bayes_pls_golite062009 |
| carbohydrate binding | 0.703854404841118 | bayes_pls_golite062009 |
| transmembrane transporter activity | 0.698240496790323 | bayes_pls_golite062009 |
| protein binding | 0.505130802921086 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.481025719380392 | bayes_pls_golite062009 |
| sugar binding | 0.466177845826757 | bayes_pls_golite062009 |
| receptor activity | 0.256839032951381 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 0.248374734969893 | bayes_pls_golite062009 |
| signal transducer activity | 0.149715597443623 | bayes_pls_golite062009 |
| molecular transducer activity | 0.149715597443623 | bayes_pls_golite062009 |
| transmembrane receptor activity | 0.0106003018506309 | bayes_pls_golite062009 |
|
Region A: Residues: [1016-1246] |
1 11 21 31 41 51
| | | | | |
1 QSLTDMWLTM LSMISGATCY ALFLGHATNL IQSLDSSRRQ YREKVKQVEE YMAYRKLPRD 60
61 MRQRITEYFE HRYQGKFFDE ELILGELSEK LREDVINYNC RSLVASVPFF ANADSNFVSD 120
121 VVTKLKYEVF QPGDIIIKEG TIGTKMYFIQ EGVVDIVMAN GEVATSLSDG SYFGEICLLT 180
181 NARRVASVRA ETYCNLFSLS VDHFNCVLDQ YPLMRKTMET VAAERLNKIG K
|
| Detection Method: | |
| Confidence: | 36.0 |
| Match: | 1q3eA |
| Description: | HCN2J 443-645 in the presence of cGMP |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| intracellular cyclic nucleotide activated cation channel activity | 11.4016635726548 | bayes_pls_golite062009 |
| cyclic nucleotide-gated ion channel activity | 11.4016635726548 | bayes_pls_golite062009 |
| intracellular ligand-gated ion channel activity | 11.0380255638103 | bayes_pls_golite062009 |
| intracellular cGMP activated cation channel activity | 9.19973076787954 | bayes_pls_golite062009 |
| cGMP binding | 7.7575871125398 | bayes_pls_golite062009 |
| ion channel activity | 7.64606920655297 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 7.59395590157869 | bayes_pls_golite062009 |
| channel activity | 7.59395590157869 | bayes_pls_golite062009 |
| substrate-specific channel activity | 7.57634767761298 | bayes_pls_golite062009 |
| cation channel activity | 7.48229936274058 | bayes_pls_golite062009 |
| ligand-gated channel activity | 7.44819644778429 | bayes_pls_golite062009 |
| ligand-gated ion channel activity | 7.44819644778429 | bayes_pls_golite062009 |
| cyclic nucleotide binding | 7.37322432929433 | bayes_pls_golite062009 |
| gated channel activity | 7.35685244969057 | bayes_pls_golite062009 |
| metal ion transmembrane transporter activity | 7.0348537556435 | bayes_pls_golite062009 |
| GMP binding | 5.49455172024846 | bayes_pls_golite062009 |
| voltage-gated ion channel activity | 4.72292819688752 | bayes_pls_golite062009 |
| voltage-gated channel activity | 4.69973028985609 | bayes_pls_golite062009 |
| potassium channel activity | 3.23703259983923 | bayes_pls_golite062009 |
| voltage-gated cation channel activity | 2.92456251340287 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 2.92372539567194 | bayes_pls_golite062009 |
| transporter activity | 2.8998330876169 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 2.89477800653409 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 2.8926771958768 | bayes_pls_golite062009 |
| transmembrane transporter activity | 2.85192191539872 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 2.55771040353717 | bayes_pls_golite062009 |
| voltage-gated potassium channel activity | 2.46282462455194 | bayes_pls_golite062009 |
| binding | 1.14074551098763 | bayes_pls_golite062009 |
| protein binding | 0.560659365968498 | bayes_pls_golite062009 |
| signal transducer activity | 0.202809682876964 | bayes_pls_golite062009 |
| molecular transducer activity | 0.202809682876964 | bayes_pls_golite062009 |
|
Region A: Residues: [1247-1327] |
1 11 21 31 41 51
| | | | | |
1 NPNIMHQKDE QLSNPESNTI TAVVNALAAE ADDCKDDDMD LKENLLHGSE SSIAEPVQTI 60
61 REGLPRPRSG EFRALFEGNT P
|
| Detection Method: | |
| Confidence: | 17.0 |
| Match: | 1ne4A |
| Description: | Crystal Structure of Rp-cAMP Binding R1a Subunit of cAMP-dependent Protein Kinase |
Matching Structure (courtesy of the PDB): |
|
