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View Structure Prediction Details

Protein: gi|77553140, gi|...
Organism: Oryza sativa Japonica Group
Length: 393 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|77553140, gi|....

Description E-value Query
Range
Subject
Range
SIR4_ARATH - NAD-dependent protein deacylase SRT2 OS=Arabidopsis thaliana GN=SRT2 PE=2 SV=1
344.0 [0..34] [391..16]

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Predicted Domain #1
Region A:
Residues: [1-96]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAGAHASRA SAPIIAGLTG ALRAAYKGFS PQLCNFHASV NNGLLHRRKI QLHFICSFRS  60
   61 IQARYNHSSA VAPKDYCETY IQFLRDKQIV PDSDPP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [97-393]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SAKDVDLLYR FIDQSKKLMV LTGAGMSTES GIPDYRSPNG AYSSGFKPLT HQEFVRSIRA  60
   61 RRRYWARSYA GWRRFRRAQP NSAHYALASL ERIGRVHSMV TQNVDRLHHR AGSKPVELHG 120
  121 SVYEVACLDC GTSIDRESFQ EQVKDLNPKW ALAIDSLEVG QPGSDKSFGM QQRPDGDIEI 180
  181 DEKFWEQDFD IPSCNQCGGV LKPDVVMFGD NVPEERAEST KEAARNCDAL LVVGSALMTM 240
  241 SAFRLARLAH EANAPIAAIT IGETRADSIL SLKINARCGE ILPRILQMGS LAVPNVS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 69.045757
Match: 1ma3A
Description: AF0112, Sir2 homolog (Sir2-AF2)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
NAD-dependent protein deacetylase activity 5.14934829690585 bayes_pls_golite062009
NAD-dependent histone deacetylase activity 5.14934829690585 bayes_pls_golite062009
histone deacetylase activity 4.99253312362199 bayes_pls_golite062009
protein deacetylase activity 4.98469537386457 bayes_pls_golite062009
NAD+ ADP-ribosyltransferase activity 4.62921662347995 bayes_pls_golite062009
deacetylase activity 3.9985462274265 bayes_pls_golite062009
transcription regulator activity 2.9155913558118 bayes_pls_golite062009
DNA binding 2.43141001866996 bayes_pls_golite062009
nucleic acid binding 2.41433477472968 bayes_pls_golite062009
transcription repressor activity 2.24657784428979 bayes_pls_golite062009
binding 2.06552694538163 bayes_pls_golite062009
transcription corepressor activity 1.64212790017753 bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 1.38412624618353 bayes_pls_golite062009
transcription factor activity 1.30143289828088 bayes_pls_golite062009
transcription factor binding 1.14766678956419 bayes_pls_golite062009
histone binding 1.08869740692996 bayes_pls_golite062009
NAD(P)+-protein-arginine ADP-ribosyltransferase activity 0.963519974868694 bayes_pls_golite062009
catalytic activity 0.739210399081789 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.62029498163975 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 0.56000396203236 bayes_pls_golite062009
transcription cofactor activity 0.54005617175343 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 0.52020182886741 bayes_pls_golite062009
protein binding 0.475479132768057 bayes_pls_golite062009
hydrogen ion transmembrane transporter activity 0.47231237137431 bayes_pls_golite062009
substrate-specific transporter activity 0.128843577740998 bayes_pls_golite062009
hydrolase activity 0.0875567934348688 bayes_pls_golite062009

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