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Protein Overview: SIR4_ARATH

General Information:
Name(s) found: SIR4_ARATH [Swiss-Prot]
Description(s) found:
Found 13 descriptions.
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  • NAD-dependent protein deacylase SRT2 OS=Arabidopsis thaliana GN=SRT2 PE=2 SV=1 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 373 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IEA]
    chromatin silencing complex [ISS]
    Biological Process: protein amino acid deacetylation [IEA]
    regulation of transcription, DNA-dependent [IEA][ISS]
    chromatin silencing [IEA][ISS]
    Molecular Function: DNA binding [IEA][ISS]
    zinc ion binding [IEA]
    NAD or NADH binding [IEA]
    NAD-dependent histone deacetylase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNMRRVFGGV STDLFPSRSM YRPLQSGGNL VMLFKGCRRF VRTTCRVSIP GGSLGNESKA  60
   61 PPRFLRDRKI VPDADPPNME DIHKLYRLFE QSSRLTILTG AGVSTECGIP DYRSPNGAYS 120
  121 SGFKPITHQE FTRSSRARRR YWARSYAGWR RFTAAQPGPA HTALASLEKA GRINFMITQN 180
  181 VDRLHHRAGS DPLELHGTVY TVMCLECGFS FPRDLFQDQL KAINPKWAEA IESIDHGDPG 240
  241 SEKSFGMKQR PDGDIEIDEK FWEEGFHIPV CEKCKGVLKP DVIFFGDNIP KERATQAMEV 300
  301 AKQSDAFLVL GSSLMTMSAF RLCRAAHEAG AMTAIVNIGE TRADDIVPLK INARVGEILH 360
  361 RVLDVGSLSV PAL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..77] deduced N/A No confident structure predictions are available.
    2 View Details [78..373] PSI-BLAST 71.69897 AF1676, Sir2 homolog (Sir2-AF1?)


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.89

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle