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View Structure Prediction Details

Protein: SIR4_ARATH
Organism: Arabidopsis thaliana
Length: 373 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SIR4_ARATH.

Description E-value Query
Range
Subject
Range
gi|9955510 - gi|9955510|emb|CAC05449.1| SIR2-family protein [Arabidopsis thaliana]
384.0 [0..11] [373..87]
gi|77553140, gi|... - gi|77553140|gb|ABA95936.1| transcriptional regulator, Sir2 family protein, expressed [Oryza sativa (...
326.0 [0..63] [371..82]
gi|92869647 - gi|92869647|gb|ABE79263.1| Silent information regulator protein Sir2 [Medicago truncatula]
321.0 [0..24] [373..37]
gi|94376711 - gi|94376711|ref|XP_996726.1| PREDICTED: similar to NAD-dependent deacetylase sirtuin-4 (SIR2-like pr...
284.0 [0..44] [365..148]
gi|91777915, gi|... - gi|91777915|ref|YP_553123.1| silent information regulator protein Sir2 [Burkholderia xenovorans LB40...
282.0 [0..53] [357..4]

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Predicted Domain #1
Region A:
Residues: [1-77]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNMRRVFGGV STDLFPSRSM YRPLQSGGNL VMLFKGCRRF VRTTCRVSIP GGSLGNESKA  60
   61 PPRFLRDRKI VPDADPP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [78-373]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NMEDIHKLYR LFEQSSRLTI LTGAGVSTEC GIPDYRSPNG AYSSGFKPIT HQEFTRSSRA  60
   61 RRRYWARSYA GWRRFTAAQP GPAHTALASL EKAGRINFMI TQNVDRLHHR AGSDPLELHG 120
  121 TVYTVMCLEC GFSFPRDLFQ DQLKAINPKW AEAIESIDHG DPGSEKSFGM KQRPDGDIEI 180
  181 DEKFWEEGFH IPVCEKCKGV LKPDVIFFGD NIPKERATQA MEVAKQSDAF LVLGSSLMTM 240
  241 SAFRLCRAAH EAGAMTAIVN IGETRADDIV PLKINARVGE ILHRVLDVGS LSVPAL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 71.69897
Match: 1m2gA
Description: AF1676, Sir2 homolog (Sir2-AF1?)
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle