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View Structure Prediction Details

Protein: gi|55638671
Organism: Pan troglodytes
Length: 478 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|55638671.

Description E-value Query
Range
Subject
Range
gi|39654787, gi|... - gi|5821858|pdb|1BOA| Chain , Human Methionine Aminopeptidase 2 Complexed With Angiogenesis Inhibit...
0.0 [1..478] [1..478]
MAP2_MOUSE - Methionine aminopeptidase 2 OS=Mus musculus GN=Metap2 PE=1 SV=1
0.0 [1..478] [1..478]
gi|114646288 - gi|114646288|ref|XP_509279.2| PREDICTED: similar to Chain , Human Methionine Aminopeptidase 2 [Pan ...
0.0 [1..478] [1..506]
gi|60552705 - gi|60552705|gb|AAH91150.1| Methionyl aminopeptidase 2 [Rattus norvegicus]
0.0 [1..478] [1..478]
gi|109098246 - gi|109098246|ref|XP_001107008.1| PREDICTED: methionyl aminopeptidase 2 isoform 4 [Macaca mulatta]
0.0 [1..478] [1..478]
gi|73977621 - gi|73977621|ref|XP_866154.1| PREDICTED: similar to Methionine aminopeptidase 2 (MetAP 2) (Peptidase ...
0.0 [1..478] [1..477]
MAP2_BOVIN - Methionine aminopeptidase 2 OS=Bos taurus GN=METAP2 PE=2 SV=1
0.0 [1..478] [1..477]

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Predicted Domain #1
Region A:
Residues: [1-478]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAGVEEVAAS GSHLNGDLDP DDREEGAAST AEEAAKKKRR KKKKSKGPSA AGEQEPDKES  60
   61 GASVDEVARQ LERSALEDKE RDEDDEDGDG DGDGATGKKK KKKKKKRGPK VQTDPPSVPI 120
  121 CDLYPNGVFP KGQECEYPPT QDGRTAAWRT TSEEKKALDQ ASEEIWNDFR EAAEAHRQVR 180
  181 KYVMSWIKPG MTMIEICEKL EDCSRKLIKE NGLNAGLAFP TGCSLNNCAA HYTPNAGDTT 240
  241 VLQYDDICKI DFGTHISGRI IDCAFTVTFN PKYDTLLKAV KDATNTGIKC AGIDVRLCDV 300
  301 GEAIQEVMES YEVEIDGKTY QVKPIRNLNG HSIGQYRIHA GKTVPIVKGG EATRMEEGEV 360
  361 YAIETFGSTG KGVVHDDMEC SHYMKNFDVG HVPIRLPRTK HLLNVINENF GTLAFCRRWL 420
  421 DRLGESKYLM ALKNLCDLGI VDPYPPLCDI KGSYTAQFEH TILLRPTCKE VVSRGDDY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 139.0
Match: 1b6aA
Description: HUMAN METHIONINE AMINOPEPTIDASE 2 COMPLEXED WITH TNP-470
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
peptidase activity 2.60615909541559 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 2.18503136472662 bayes_pls_golite062009
sequence-specific DNA binding 1.8401324043677 bayes_pls_golite062009
transcription activator activity 1.69071209162619 bayes_pls_golite062009
transcription repressor activity 1.54960543048317 bayes_pls_golite062009
hydrolase activity 1.43646476372001 bayes_pls_golite062009
binding 1.30837875079167 bayes_pls_golite062009
nucleic acid binding 1.07337728528324 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.0361110104194 bayes_pls_golite062009
transcription regulator activity 0.977875027333104 bayes_pls_golite062009
aminopeptidase activity 0.89399203910285 bayes_pls_golite062009
DNA binding 0.772721556221145 bayes_pls_golite062009
exopeptidase activity 0.762255574851485 bayes_pls_golite062009
metallopeptidase activity 0.629480947971878 bayes_pls_golite062009
protein binding 0.378185804009078 bayes_pls_golite062009
structural constituent of ribosome 0.278734480962003 bayes_pls_golite062009
structural molecule activity 0.276811112308517 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.249771970501337 bayes_pls_golite062009
catalytic activity 0.148551873544128 bayes_pls_golite062009
transcription factor activity 0.143705860811928 bayes_pls_golite062009
transcription factor binding 0.13558561552621 bayes_pls_golite062009
transferase activity 0.064832527337659 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle