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View Structure Prediction Details

Protein: FBpp0298328, FBp...
Organism: Drosophila melanogaster
Length: 730 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0298328, FBp....

Description E-value Query
Range
Subject
Range
gi|62861862, gi|... - gi|62861862|ref|NP_001015077.1| CG17469-PA.3 [Drosophila melanogaster], gi|51950990|gb|EAL24533.1| C...
231.0 [0..93] [730..3]

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Predicted Domain #1
Region A:
Residues: [1-210]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTESGIDLGF DMEFDLNINL LNDNDNMDFL PNVTENMEFY ELKSSSRCIR HNEIPTFKTA  60
   61 TPTSRTQLKL QLQREQQQQM MIQQQTLDTA MDPKMHLLFG SGQGLMESEF IDSGSTSACG 120
  121 SGSSSLEQMS QLVQMDNLID SSSGAKLKVP LQSIGVDVPP QVLQVSTVLE NPTRYHVIQK 180
  181 QKNQVRQYLS ESFKPSMWGS HTSEIKLANN 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.045757
Match: 1m2vB
Description: Sec24
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [211-357]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SASTGNLQNS SLQKGICDPL ERTNRFGCDS AVSAKRIMPS DDAMPISPFG GSFVRCDDIN  60
   61 PIEPTVLRPN SHGAGEPENA HRTAQLGLSK ANSSLSSTRS SSGIVNSIRI SSTSSSLQST 120
  121 SAPISPSVSS VATSVSELPS FDSDPDD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [358-540]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IFDDILQNDS FNFDKNFNSE LSIKQEPQNL TDAEMNALAK DRQKKDNHNM IERRRRFNIN  60
   61 DRIKELGTLL PKGSDAFYEV VRDIRPNKGT ILKSSVDYIK CLKHEVTRLR QNELRQRQVE 120
  121 LQNRKLMSRI KELEMQAKSH GILLSENHLT SLSAPTQPYL KSFSLSPTAS RSRRSLFDQP 180
  181 VEK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.39794
Match: 1r05A
Description: Solution Structure of Max B-HLH-LZ
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 5.38658950816179 bayes_pls_golite062009
DNA binding 5.18654839258297 bayes_pls_golite062009
nucleic acid binding 5.05768805749761 bayes_pls_golite062009
transcription factor activity 4.78039531631248 bayes_pls_golite062009
transcription activator activity 3.87875547821718 bayes_pls_golite062009
binding 3.81829206350975 bayes_pls_golite062009
sequence-specific DNA binding 3.42035985454056 bayes_pls_golite062009
RNA polymerase II transcription factor activity 3.39500382187264 bayes_pls_golite062009
protein binding 2.64975291677725 bayes_pls_golite062009
transcription factor binding 2.61163564741984 bayes_pls_golite062009
RNA polymerase II transcription factor activity, enhancer binding 2.42306484786159 bayes_pls_golite062009
transcription cofactor activity 1.52770895937238 bayes_pls_golite062009
transcription repressor activity 0.955588849035129 bayes_pls_golite062009
promoter binding 0.8576109846276 bayes_pls_golite062009
transcription corepressor activity 0.801830750183111 bayes_pls_golite062009
protein heterodimerization activity 0.53175615551166 bayes_pls_golite062009
transcription coactivator activity 0.3513586903977 bayes_pls_golite062009
protein dimerization activity 0.20674648626116 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [541-730]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KIQVIDGADG NMGMNQVDEF MEDCKYAVQG GDPMLSSHSH MQSAPQSPSS KTLNSGSFEP  60
   61 KNFSEADESL FRGKSSLASD DCCGINCSTS CYIQHQLTSR EGHPNHSHHT GIREIHSLSD 120
  121 SAQNSEFSRL EHCDDPLLSS SHRSLGTVDE DQHNSVDMSA VMVHDSLSSL VDDNNSETMV 180
  181 LASDTLDIEL 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle