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View Structure Prediction Details

Protein: FBpp0298328, FBp...
Organism: Drosophila melanogaster
Length: 730 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0298328, FBp....

Description E-value Query
Range
Subject
Range
gi|62861862, gi|... - gi|62861862|ref|NP_001015077.1| CG17469-PA.3 [Drosophila melanogaster], gi|51950990|gb|EAL24533.1| C...
231.0 [0..93] [730..3]

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Predicted Domain #1
Region A:
Residues: [1-210]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTESGIDLGF DMEFDLNINL LNDNDNMDFL PNVTENMEFY ELKSSSRCIR HNEIPTFKTA  60
   61 TPTSRTQLKL QLQREQQQQM MIQQQTLDTA MDPKMHLLFG SGQGLMESEF IDSGSTSACG 120
  121 SGSSSLEQMS QLVQMDNLID SSSGAKLKVP LQSIGVDVPP QVLQVSTVLE NPTRYHVIQK 180
  181 QKNQVRQYLS ESFKPSMWGS HTSEIKLANN 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.045757
Match: 1m2vB
Description: Sec24
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [211-357]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SASTGNLQNS SLQKGICDPL ERTNRFGCDS AVSAKRIMPS DDAMPISPFG GSFVRCDDIN  60
   61 PIEPTVLRPN SHGAGEPENA HRTAQLGLSK ANSSLSSTRS SSGIVNSIRI SSTSSSLQST 120
  121 SAPISPSVSS VATSVSELPS FDSDPDD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [358-540]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IFDDILQNDS FNFDKNFNSE LSIKQEPQNL TDAEMNALAK DRQKKDNHNM IERRRRFNIN  60
   61 DRIKELGTLL PKGSDAFYEV VRDIRPNKGT ILKSSVDYIK CLKHEVTRLR QNELRQRQVE 120
  121 LQNRKLMSRI KELEMQAKSH GILLSENHLT SLSAPTQPYL KSFSLSPTAS RSRRSLFDQP 180
  181 VEK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.39794
Match: 1r05A
Description: Solution Structure of Max B-HLH-LZ
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 5.38658950816179 bayes_pls_golite062009
DNA binding 5.18654839258297 bayes_pls_golite062009
nucleic acid binding 5.05768805749761 bayes_pls_golite062009
transcription factor activity 4.78039531631248 bayes_pls_golite062009
transcription activator activity 3.87875547821718 bayes_pls_golite062009
binding 3.81829206350975 bayes_pls_golite062009
sequence-specific DNA binding 3.42035985454056 bayes_pls_golite062009
RNA polymerase II transcription factor activity 3.39500382187264 bayes_pls_golite062009
protein binding 2.64975291677725 bayes_pls_golite062009
transcription factor binding 2.61163564741984 bayes_pls_golite062009
RNA polymerase II transcription factor activity, enhancer binding 2.42306484786159 bayes_pls_golite062009
transcription cofactor activity 1.52770895937238 bayes_pls_golite062009
transcription repressor activity 0.955588849035129 bayes_pls_golite062009
promoter binding 0.8576109846276 bayes_pls_golite062009
transcription corepressor activity 0.801830750183111 bayes_pls_golite062009
protein heterodimerization activity 0.53175615551166 bayes_pls_golite062009
transcription coactivator activity 0.3513586903977 bayes_pls_golite062009
protein dimerization activity 0.20674648626116 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [541-730]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KIQVIDGADG NMGMNQVDEF MEDCKYAVQG GDPMLSSHSH MQSAPQSPSS KTLNSGSFEP  60
   61 KNFSEADESL FRGKSSLASD DCCGINCSTS CYIQHQLTSR EGHPNHSHHT GIREIHSLSD 120
  121 SAQNSEFSRL EHCDDPLLSS SHRSLGTVDE DQHNSVDMSA VMVHDSLSSL VDDNNSETMV 180
  181 LASDTLDIEL 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle