YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|65319169, gi\|...
Organism:	Bacillus anthracis str. A2012
Length:	570 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|65319169, gi|....

Description	E-value	Query Range	Subject Range
gi\|219993234, gi... - gi\|89210057\|ref\|ZP_01188450.1\| Acetolactate synthase, large subunit, biosynthetic type [Halothermoth...	0.0	[12..564]	[1..553]
gi\|49481115, gi\|... - gi\|49481115\|ref\|YP_036023.1\| acetolactate synthase 3 catalytic subunit [Bacillus thuringiensis serov...	0.0	[1..570]	[1..570]
gi\|91202797 - gi\|91202797\|emb\|CAJ72436.1\| strongly similar to acetohydroxy acid synthase IilvB [Candidatus Kueneni...	0.0	[11..564]	[7..561]
gi\|21226772, gi\|... - gi\|21226772\|ref\|NP_632694.1\| acetolactate synthase 3 catalytic subunit [Methanosarcina mazei Go1], g...	0.0	[8..564]	[2..558]
gi\|228638912, gi... - gi\|229144499\|ref\|ZP_04272902.1\| hypothetical protein bcere0012_16590 [Bacillus cereus BDRD-ST24], gi... gi\|228656324, gi... - gi\|229127208\|ref\|ZP_04256205.1\| hypothetical protein bcere0015_16620 [Bacillus cereus BDRD-Cer4], gi... gi\|228725719, gi... - gi\|229043644\|ref\|ZP_04191351.1\| hypothetical protein bcere0027_16920 [Bacillus cereus AH676], gi\|228... gi\|30019920, gi\|... - gi\|30019920\|ref\|NP_831551.1\| acetolactate synthase 3 catalytic subunit [Bacillus cereus ATCC 14579],...	0.0	[1..570]	[3..573]
gi\|228900467, gi... - gi\|228900467\|ref\|ZP_04064694.1\| hypothetical protein bthur0014_16740 [Bacillus thuringiensis IBL 422... gi\|74491570, gi\|... - gi\|75760933\|ref\|ZP_00740942.1\| Acetolactate synthase large subunit [Bacillus thuringiensis serovar i...	0.0	[1..570]	[1..571]
gi\|88602528, gi\|... - gi\|88602528\|ref\|YP_502706.1\| acetolactate synthase, large subunit, biosynthetic type [Methanospirill...	0.0	[14..566]	[1..555]
gi\|17232105, gi\|... - gi\|17232105\|ref\|NP_488653.1\| acetolactate synthase 3 catalytic subunit [Nostoc sp. PCC 7120], gi\|171... gi\|25291313 - pir\|\|AE2382 acetohydroxy acid synthase [imported] - Nostoc sp. (strain PCC 7120)	0.0	[2..567]	[20..599]
gi\|75908969, gi\|... - gi\|75908969\|ref\|YP_323265.1\| acetolactate synthase 3 catalytic subunit [Anabaena variabilis ATCC 294...	0.0	[2..567]	[20..599]
gi\|228616755, gi... - gi\|229166758\|ref\|ZP_04294508.1\| hypothetical protein bcere0007_17280 [Bacillus cereus AH621], gi\|228... gi\|163861887, gi... - gi\|89205133\|ref\|ZP_01183705.1\| Acetolactate synthase, large subunit, biosynthetic type [Bacillus wei...	0.0	[3..570]	[4..571]

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Predicted Domain #1

Region A:
Residues: [1-570]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKQYTTYEKL QCEEVTGAGH VIQCLKKLGV TTVFGYPGGA ILPVYDALYE SGLKHILTRH  60
   61 EQAAIHAAEG YARASGKVGV VFATSGPGAT NLVTGLADAY MDSIPLVVIT GQVATPLIGK 120
  121 DGFQEADVVG ITVPVTKHNY QVRDVNQLSR IVQEAFYIAE SGRPGPVLID IPKDVQIEKV 180
  181 TSFYNEVIEI PGYKLEPRPD SMKLREVAKA ISEAKRPLLY IGGGIIHADG SEELIQFARK 240
  241 KGIPVVSTLM GLGAYPPGDP LFLGMLGMHG TYAANMAVTE CDLLLALGVR FDDRVTGKLE 300
  301 LFSPHSKKVH IDIDPSEFQK NVAVEYPVVG DVKKALHMLL HMSIHTQTDE WLQKVKTWKE 360
  361 EYQLSYKQKE SELKPQHVIN LVSELTNGEA IVTTEVGQHQ MWAAHFYKAK NPRTFLTSGG 420
  421 LGTMGFGFPA AIGAQLAKEE ELVICIAGDA SFQMNIQELQ TIAENNIPVK VFIINNKFLG 480
  481 MVRQWQEMFY ENRLSESKIG SPDFVKVAEA YGVKGLRATN ATEAKQVMLE AFAHKGPVVV 540
  541 DFCVEEGENV FPMVPPNKGN NEMIMKRWEE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	147.0
Match:	1ybhA
Description:	Crystal structure of Arabidopsis thaliana Acetohydroxyacid synthase In Complex With A Sulfonylurea Herbicide Chlorimuron Ethyl
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
acetolactate synthase activity	12.903449876837	bayes_pls_golite062009
transferase activity, transferring aldehyde or ketonic groups	12.3239025230705	bayes_pls_golite062009
pyruvate dehydrogenase activity	5.28857071459273	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	5.21233670052586	bayes_pls_golite062009
pyruvate dehydrogenase (acetyl-transferring) activity	5.08663245333808	bayes_pls_golite062009
transketolase activity	2.50501741089295	bayes_pls_golite062009
catalytic activity	2.25537597692103	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors	2.15444163802756	bayes_pls_golite062009
deoxyhypusine synthase activity	2.04735838056767	bayes_pls_golite062009
hydrogen ion transmembrane transporter activity	1.98546381612935	bayes_pls_golite062009
thiamin pyrophosphate binding	1.87247313698582	bayes_pls_golite062009
oxidoreductase activity	1.85833680148029	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	1.82969293063325	bayes_pls_golite062009
3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity	1.65348126142808	bayes_pls_golite062009
alpha-ketoacid dehydrogenase activity	1.20517690263403	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	1.0611726850452	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH	0.982646671777	bayes_pls_golite062009
binding	0.980920092099572	bayes_pls_golite062009
histone deacetylase activity	0.9493052849746	bayes_pls_golite062009
protein deacetylase activity	0.942714095508542	bayes_pls_golite062009
transcription regulator activity	0.872247149132548	bayes_pls_golite062009
NAD-dependent histone deacetylase activity	0.86895852396873	bayes_pls_golite062009
NAD-dependent protein deacetylase activity	0.86895852396873	bayes_pls_golite062009
cation transmembrane transporter activity	0.78591260444574	bayes_pls_golite062009
nucleic acid binding	0.625412573920025	bayes_pls_golite062009
DNA binding	0.56819169389651	bayes_pls_golite062009
hydrolase activity	0.536729211484905	bayes_pls_golite062009
ion transmembrane transporter activity	0.51426028502998	bayes_pls_golite062009
transferase activity	0.413024577830522	bayes_pls_golite062009
deacetylase activity	0.34210759801484	bayes_pls_golite062009
pyruvate decarboxylase activity	0.198062360371269	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	0.114062221123972	bayes_pls_golite062009
transcription factor binding	0.0144694403853303	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: