YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30261011, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	518 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30261011, gi|....

Description	E-value	Query Range	Subject Range
gi\|56419203, gi\|... - gi\|56419203\|ref\|YP_146521.1\| acyl-CoA synthetase [Geobacillus kaustophilus HTA426], gi\|56379045\|dbj\|...	0.0	[3..514]	[1..510]
gi\|77996178, gi\|... - gi\|78044063\|ref\|YP_360551.1\| long-chain-fatty-acid--CoA ligase [Carboxydothermus hydrogenoformans Z-...	0.0	[4..518]	[28..544]
gi\|53763480, gi\|... - gi\|75910191\|ref\|YP_324487.1\| AMP-dependent synthetase and ligase [Anabaena variabilis ATCC 29413], g...	0.0	[3..512]	[1..496]
gi\|106772735, gi... - gi\|148656221\|ref\|YP_001276426.1\| AMP-dependent synthetase and ligase [Roseiflexus sp. RS-1], gi\|1485...	0.0	[1..516]	[1..511]
gi\|52079510, gi\|... - gi\|52784875\|ref\|YP_090704.1\| acyl-CoA synthetase [Bacillus licheniformis ATCC 14580], gi\|52347377\|gb...	0.0	[3..513]	[1..509]
gi\|55981432, gi\|... - gi\|55981432\|ref\|YP_144729.1\| long-chain-fatty-acid--CoA ligase [Thermus thermophilus HB8], gi\|557728...	0.0	[4..517]	[27..559]
gi\|29894587, gi\|... - gi\|30019045\|ref\|NP_830676.1\| acyl-CoA synthetase [Bacillus cereus ATCC 14579], gi\|29894587\|gb\|AAP078... gi\|229143593, gi... - gi\|229143593\|ref\|ZP_04272017.1\| Acyl-CoA synthase [Bacillus cereus BDRD-ST24], gi\|228639850\|gb\|EEK96... gi\|229126300, gi... - gi\|229126300\|ref\|ZP_04255318.1\| Acyl-CoA synthase [Bacillus cereus BDRD-Cer4], gi\|228657292\|gb\|EEL13... gi\|228726575, gi... - gi\|229042741\|ref\|ZP_04190480.1\| Acyl-CoA synthase [Bacillus cereus AH676], gi\|228726575\|gb\|EEL77793....	0.0	[1..518]	[1..518]
gi\|42780041, gi\|... - gi\|42780041\|ref\|NP_977288.1\| acyl-CoA synthetase [Bacillus cereus ATCC 10987], gi\|42735959\|gb\|AAS398...	0.0	[1..518]	[1..518]
gi\|46197026, gi\|... - gi\|46199401\|ref\|YP_005068.1\| long-chain-fatty-acid-CoA ligase [Thermus thermophilus HB27], gi\|461970...	0.0	[4..517]	[27..559]

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Predicted Domain #1

Region A:
Residues: [1-518]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYMTVGRIFD LSVGKYPNKE ALVEPEKNIR WTYKQWDEQI NKTAHALLEE GVRKGDTVSV  60
   61 YLYNCREFVN VYLACAKIGA IFNPINFRLK AKEVSYILQD AFSKVVVFEK AVESTVAIIE 120
  121 RDFPNASFWY VEDDTPSYAS SYHEKVNAAS SKKIDIEINE MDYCSMLYTS GTTGHPKGVL 180
  181 HRHREMAEHS MICTYFLKYN RDSVGLVVAP LYHCGELNAG IIPRIQVGGK NVILHHFDTE 240
  241 TVLHTIQEEK ITTFFAAPTM WNMLLQKDLT QYDLTSMKIG IYGGAAMAPA LVKECKERLY 300
  301 IDLVQIYGMT EMGPVVAFLV EEDQITKAGS AGTPCFSHEI RIVKPSEDAP AEPDDVLPPY 360
  361 EVGEIILRGP TMMAGYHNRE EANVKSMYKG WYHSGDLGYF DKDGYLFVAD RVDDMVISGG 420
  421 VNIYPREIED FLHSHPGILD VAVLGEPDEL WGERVVAVVV KKDKNISEAD LETYCKESDE 480
  481 LADYKRPRHY LFVDELPRNA SGKLQKFVLR ESLKGAKK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	108.0
Match:	1ultA
Description:	Crystal structure of tt0168 from Thermus thermophilus HB8
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ligase activity, forming carbon-sulfur bonds	5.10123876514454	bayes_pls_golite062009
fatty acid ligase activity	4.83067429373059	bayes_pls_golite062009
long-chain fatty acid transporter activity	4.82574147628486	bayes_pls_golite062009
fatty acid transporter activity	4.78347692728947	bayes_pls_golite062009
long-chain fatty acid-CoA ligase activity	4.72692389032116	bayes_pls_golite062009
acetate-CoA ligase activity	4.48129067128523	bayes_pls_golite062009
acid-thiol ligase activity	4.28278725989432	bayes_pls_golite062009
CoA-ligase activity	4.12850865352867	bayes_pls_golite062009
Photinus-luciferin 4-monooxygenase (ATP-hydrolyzing) activity	2.74744781333102	bayes_pls_golite062009
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)	2.74744781333102	bayes_pls_golite062009
luciferin monooxygenase activity	2.67396462766343	bayes_pls_golite062009
lipid transporter activity	2.59608399999188	bayes_pls_golite062009
ligase activity	2.49556073715112	bayes_pls_golite062009
transcription regulator activity	2.31193176808353	bayes_pls_golite062009
catalytic activity	1.83545185797733	bayes_pls_golite062009
binding	1.5312519256537	bayes_pls_golite062009
transporter activity	1.29780964436121	bayes_pls_golite062009
transcription repressor activity	1.2638869228049	bayes_pls_golite062009
transmembrane transporter activity	1.07143339827205	bayes_pls_golite062009
substrate-specific transporter activity	1.03753946113449	bayes_pls_golite062009
monooxygenase activity	0.725493998442316	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	0.54797726647835	bayes_pls_golite062009
transferase activity, transferring acyl groups	0.464663038956639	bayes_pls_golite062009
active transmembrane transporter activity	0.251681382273558	bayes_pls_golite062009
primary active transmembrane transporter activity	0.225448500718996	bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity	0.216579620878492	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	0.177812048124158	bayes_pls_golite062009
ATPase activity, coupled to movement of substances	0.174283007890308	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances	0.173963339749644	bayes_pls_golite062009
nucleoside-triphosphatase activity	0.0401881910649647	bayes_pls_golite062009
pyrophosphatase activity	0.0047964784091391	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: