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View Structure Prediction Details

Protein: KAD_COXBU
Organism: Coxiella burnetii RSA 493
Length: 231 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for KAD_COXBU.

Description E-value Query
Range		 Subject
Range
KAD_BORP1 - Adenylate kinase OS=Bordetella pertussis (strain ATCC 9797 / DSM 5571 / NCTC 10739 / 18323) GN=adk P...
KAD_BORBR - Adenylate kinase OS=Bordetella bronchiseptica GN=adk PE=3 SV=1
KAD_BORBR - Adenylate kinase OS=Bordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50) GN=adk PE=3 ...
 229.0 [0..3] [220..1]
KAD_ACIAC - Adenylate kinase OS=Acidovorax citrulli (strain AAC00-1) GN=adk PE=3 SV=1
 228.0 [0..3] [219..1]
KAD_BORPA - Adenylate kinase OS=Bordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253) GN=adk PE=3 ...
KAD_BORPA - Adenylate kinase OS=Bordetella parapertussis GN=adk PE=3 SV=1
 228.0 [0..3] [220..1]
KAD_BORPE - Adenylate kinase OS=Bordetella pertussis GN=adk PE=3 SV=1
gi|453621|emb|CA... - adenylate kinase [Bordetella pertussis]
KAD_BORPE - Adenylate kinase OS=Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251) GN=adk PE=3 S...
 227.0 [0..3] [220..1]
KAD_POLSJ - Adenylate kinase OS=Polaromonas sp. (strain JS666 / ATCC BAA-500) GN=adk PE=3 SV=1
 226.0 [0..3] [220..1]
KAD_POLNA - Adenylate kinase OS=Polaromonas naphthalenivorans (strain CJ2) GN=adk PE=3 SV=1
 225.0 [0..3] [220..1]
KAD_BORA1 - Adenylate kinase OS=Bordetella avium (strain 197N) GN=adk PE=3 SV=1
 224.0 [0..3] [220..1]
KAD_HALHL - Adenylate kinase OS=Halorhodospira halophila (strain DSM 244 / SL1) GN=adk PE=3 SV=1
 223.0 [0..3] [221..1]
KAD_ALKEH - Adenylate kinase OS=Alkalilimnicola ehrlichii (strain ATCC BAA-1101 / DSM 17681 / MLHE-1) GN=adk PE=...
 223.0 [0..3] [220..1]
KAD_AROAE - Adenylate kinase OS=Aromatoleum aromaticum (strain EbN1) GN=adk PE=3 SV=1
 222.0 [0..3] [219..1]

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Predicted Domain #1
Region A:
Residues: [1-231] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPLRIILLGL PGAGKGTQAD FIAKHLDIPK ISTGDMLRAA VKAKTPLGLE VKKIMESGGL  60
   61 VSDEIMIALV KERVKLPDCH KGYLLDGFPR TLAQADALNA AAIKIDLVIE IDVPEEEIIE 120
  121 RMTGRLIHPA SGRTYHRRYN PPKVADKDDV TGEPLIQRAD DREETVRHRL AVYRKQTSPL 180
  181 SDYYAQWEKS GDPQAPKYFR ISGLGSMEEV RERILQVFEA YDPRDSGNLE H

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 55.0
Match: 1akeA
Description: Adenylate kinase; Microbial and mitochondrial ADK, insert "zinc finger" domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nucleobase, nucleoside, nucleotide kinase activity 5.63633783771436 bayes_pls_golite062009
nucleotide kinase activity 4.87013305162694 bayes_pls_golite062009
phosphotransferase activity, phosphate group as acceptor 4.71956130169341 bayes_pls_golite062009
adenylate kinase activity 3.67594732794865 bayes_pls_golite062009
transporter activity 3.06347241703095 bayes_pls_golite062009
transmembrane transporter activity 2.92178249124988 bayes_pls_golite062009
nucleoside-triphosphatase activity 2.72471277217637 bayes_pls_golite062009
pyrophosphatase activity 2.65178178494722 bayes_pls_golite062009
binding 2.64537357529343 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 2.6324074638534 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 2.62930532133361 bayes_pls_golite062009
active transmembrane transporter activity 2.47371672314006 bayes_pls_golite062009
primary active transmembrane transporter activity 2.36656376979386 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 2.36628513972722 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 2.33101326378731 bayes_pls_golite062009
ATPase activity, coupled to movement of substances 2.32956222649229 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances 2.32729839766053 bayes_pls_golite062009
hydrogen ion transporting ATP synthase activity, rotational mechanism 2.29455092461489 bayes_pls_golite062009
ATPase activity 2.23432662573776 bayes_pls_golite062009
ATPase activity, coupled 2.22021172695288 bayes_pls_golite062009
substrate-specific transporter activity 1.62497652645669 bayes_pls_golite062009
hydrogen ion transmembrane transporter activity 1.39044805677656 bayes_pls_golite062009
hydrolase activity 1.32740066346416 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 1.28936854749141 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 1.27520023113176 bayes_pls_golite062009
protein binding 1.22129154759482 bayes_pls_golite062009
nucleic acid binding 1.08697924060619 bayes_pls_golite062009
catalytic activity 1.00104173493322 bayes_pls_golite062009
guanylate kinase activity 0.98934362137863 bayes_pls_golite062009
purine nucleotide binding 0.912853112793192 bayes_pls_golite062009
nucleotide binding 0.905342574142397 bayes_pls_golite062009
purine ribonucleotide binding 0.904115761720541 bayes_pls_golite062009
ribonucleotide binding 0.904053997411779 bayes_pls_golite062009
GTPase activity 0.83849854735032 bayes_pls_golite062009
protein transporter activity 0.712797684532763 bayes_pls_golite062009
motor activity 0.70874549510465 bayes_pls_golite062009
DNA binding 0.702147676354075 bayes_pls_golite062009
ion transmembrane transporter activity 0.678463776360409 bayes_pls_golite062009
CTP synthase activity 0.554689818807922 bayes_pls_golite062009
microtubule motor activity 0.48522137429998 bayes_pls_golite062009
ATP binding 0.38929752840764 bayes_pls_golite062009
adenyl ribonucleotide binding 0.364108656344062 bayes_pls_golite062009
adenyl nucleotide binding 0.356069365520539 bayes_pls_golite062009
transcription regulator activity 0.312171320541728 bayes_pls_golite062009
cation transmembrane transporter activity 0.256834704602307 bayes_pls_golite062009
helicase activity 0.0775311459068899 bayes_pls_golite062009
formate-tetrahydrofolate ligase activity 0.00346797313746072 bayes_pls_golite062009
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