YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|24349405, gi\|...
Organism:	Shewanella oneidensis MR-1
Length:	360 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|24349405, gi|....

Description	E-value	Query Range	Subject Range
gi\|94263692, gi\|... - gi\|94263692\|ref\|ZP_01287500.1\| PAS:ATP-binding region, ATPase-like:Histidine kinase A-like [delta pr...	204.0	[0..2]	[360..116]
gi\|51974390, gi\|... - gi\|52140921\|ref\|YP_085908.1\| phosphate regulon sensor protein [Bacillus cereus E33L], gi\|51974390\|gb...	203.0	[0..6]	[350..218]
gi\|47557784, gi\|... - gi\|47564998\|ref\|ZP_00236041.1\| sensory box histidine kinase PhoR [Bacillus cereus G9241], gi\|4755778...	203.0	[0..6]	[350..218]
gi\|89154470, gi\|... - gi\|89207576\|ref\|ZP_01186114.1\| PAS [Bacillus weihenstephanensis KBAB4], gi\|89154470\|gb\|EAR74501.1\| P...	203.0	[0..6]	[350..218]
gi\|49330250, gi\|... - gi\|49478694\|ref\|YP_038633.1\| phosphate regulon sensor protein [Bacillus thuringiensis serovar konkuk...	203.0	[0..6]	[350..218]
gi\|30264658, gi\|... - gi\|30264658\|ref\|NP_847035.1\| sensory box histidine kinase PhoR [Bacillus anthracis str. Ames], gi\|30... gi\|65321955, gi\|... - gi\|65321955\|ref\|ZP_00394914.1\| COG0642: Signal transduction histidine kinase [Bacillus anthracis str... gi\|165869708, gi... - gi\|165869708\|ref\|ZP_02214366.1\| sensory box histidine kinase PhoR [Bacillus anthracis str. A0488], g... gi\|167530779, gi... - gi\|167633978\|ref\|ZP_02392301.1\| sensory box histidine kinase PhoR [Bacillus anthracis str. A0442], g... gi\|167513830, gi... - gi\|167638013\|ref\|ZP_02396291.1\| sensory box histidine kinase PhoR [Bacillus anthracis str. A0193], g... gi\|47530128, gi\|... - gi\|47530128\|ref\|YP_021477.1\| sensory box histidine kinase PhoR [Bacillus anthracis str. 'Ames Ancest... gi\|170685740, gi... - gi\|170685740\|ref\|ZP_02876963.1\| sensory box histidine kinase PhoR [Bacillus anthracis str. A0465], g... gi\|254757502 - gi\|254757502\|ref\|ZP_05209529.1\| sensory box histidine kinase PhoR [Bacillus anthracis str. Australia... gi\|254754670 - gi\|254754670\|ref\|ZP_05206705.1\| sensory box histidine kinase PhoR [Bacillus anthracis str. Vollum] gi\|254741732 - gi\|254741732\|ref\|ZP_05199419.1\| sensory box histidine kinase PhoR [Bacillus anthracis str. Kruger B] gi\|254736695 - gi\|254736695\|ref\|ZP_05194401.1\| sensory box histidine kinase PhoR [Bacillus anthracis str. Western N... gi\|254724958 - gi\|254724958\|ref\|ZP_05186741.1\| sensory box histidine kinase PhoR [Bacillus anthracis str. A1055] gi\|254687395 - gi\|254687395\|ref\|ZP_05151251.1\| sensory box histidine kinase PhoR [Bacillus anthracis str. CNEVA-906... gi\|229264805, gi... - gi\|229600397\|ref\|YP_002868867.1\| sensory box histidine kinase PhoR [Bacillus anthracis str. A0248], ... gi\|170705359, gi... - gi\|170705359\|ref\|ZP_02895823.1\| sensory box histidine kinase PhoR [Bacillus anthracis str. A0389], g... gi\|227004296, gi... - gi\|227817372\|ref\|YP_002817381.1\| sensory box histidine kinase PhoR [Bacillus anthracis str. CDC 684]... gi\|177651147, gi... - gi\|177651147\|ref\|ZP_02933978.1\| sensory box histidine kinase PhoR [Bacillus anthracis str. A0174], g... gi\|190559871, gi... - gi\|190569089\|ref\|ZP_03021989.1\| sensory box histidine kinase PhoR [Bacillus anthracis Tsiankovskii-I... gi\|196032783, gi... - gi\|196032783\|ref\|ZP_03100196.1\| sensory box histidine kinase PhoR [Bacillus cereus W], gi\|195994212\|... gi\|218905815, gi... - gi\|218905815\|ref\|YP_002453649.1\| sensory box histidine kinase PhoR [Bacillus cereus AH820], gi\|21854...	203.0	[0..6]	[350..218]
gi\|49187478, gi\|... - gi\|49187478\|ref\|YP_030730.1\| sensory box histidine kinase PhoR [Bacillus anthracis str. Sterne], gi\|...	203.0	[0..6]	[350..218]
gi\|42783765, gi\|... - gi\|42783765\|ref\|NP_981012.1\| sensory box histidine kinase PhoR [Bacillus cereus ATCC 10987], gi\|4273...	203.0	[0..6]	[350..218]
gi\|30022663, gi\|... - gi\|30022663\|ref\|NP_834294.1\| phosphate regulon sensor protein phoR [Bacillus cereus ATCC 14579], gi\|...	202.0	[0..6]	[350..218]

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Predicted Domain #1

Region A:
Residues: [1-109]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSAHPLAQLE TFKHTSKQWN QLREAANMSN RMEHILQAMP SGVVILNGDG IVTDANPVAV  60
   61 ELLEQSLCGA RWIDVIHTAF APQDDDGHEV SLRNGRRVKL AITPLTPEP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	3.69897
Match:	1d06A
Description:	Histidine kinase FixL heme domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ion transmembrane transporter activity	1.94020112661684	bayes_pls_golite062009
binding	1.79230776794479	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	1.70629448457771	bayes_pls_golite062009
cation transmembrane transporter activity	1.55042643398568	bayes_pls_golite062009
two-component response regulator activity	1.45691562840107	bayes_pls_golite062009
metal ion transmembrane transporter activity	1.31850321187865	bayes_pls_golite062009
transcription regulator activity	1.13913685347546	bayes_pls_golite062009
protein binding	1.0133195984081	bayes_pls_golite062009
potassium channel activity	0.93265112299626	bayes_pls_golite062009
voltage-gated ion channel activity	0.92661046549451	bayes_pls_golite062009
voltage-gated cation channel activity	0.926512767264521	bayes_pls_golite062009
voltage-gated potassium channel activity	0.92204538811959	bayes_pls_golite062009
voltage-gated channel activity	0.91469735366704	bayes_pls_golite062009
ion channel activity	0.75430461252947	bayes_pls_golite062009
cation channel activity	0.73262554730695	bayes_pls_golite062009
DNA binding	0.73243452463464	bayes_pls_golite062009
gated channel activity	0.67217953143815	bayes_pls_golite062009
substrate-specific channel activity	0.650205954115699	bayes_pls_golite062009
channel activity	0.64202076714636	bayes_pls_golite062009
passive transmembrane transporter activity	0.64202076714636	bayes_pls_golite062009
two-component sensor activity	0.58151911764083	bayes_pls_golite062009
protein histidine kinase activity	0.56538125817883	bayes_pls_golite062009
nucleic acid binding	0.5545839402512	bayes_pls_golite062009
phosphotransferase activity, nitrogenous group as acceptor	0.518111391350209	bayes_pls_golite062009
signal transducer activity	0.441034662376355	bayes_pls_golite062009
molecular transducer activity	0.441034662376355	bayes_pls_golite062009
transcription factor activity	0.36759096137141	bayes_pls_golite062009
transporter activity	0.360938622392148	bayes_pls_golite062009
catalytic activity	0.285447488878019	bayes_pls_golite062009
transmembrane transporter activity	0.217804199010847	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [110-360]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GQLIVLTDLT ETRLLQKNLS HLQRLSALGK MVATLAHQVR TPLSAALLYA ANLASPKLSD  60
   61 SAKVKFQQKL VDRLNELERQ VNDMLLMAKG RQDELGELIN LNDVIENVVA NCEPIVAKHG 120
  121 AELTVTNASN GLMLANVNAL SSAVNNLVMN SLEAGATQIQ LVANEIDDQL HLNVVDNGKG 180
  181 LDAKMQQRVL EPFFTTKAQG TGLGLAVVQS VVRNHGGQLQ LNCMPNKGCT VSLTFPQAKS 240
  241 ATVLPLEKSH V

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	35.0
Match:	2c2aA
Description:	Structure of the entire cytoplasmic portion of a sensor histidine kinase protein
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: