YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: IMB1_YEAST
Organism: Saccharomyces cerevisiae S288c
Length: 861 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for IMB1_YEAST.

Description E-value Query
Range		 Subject
Range
IMB1_YEAST - Importin subunit beta-1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=KAP95 PE=1 SV=1
KAP95 - Karyopherin beta, forms a complex with Srp1p/Kap60p; interacts with nucleoporins to mediate nuclear ...
 0.0 [1..861] [1..861]
IMB1_MOUSE - Importin subunit beta-1 OS=Mus musculus GN=Kpnb1 PE=1 SV=1
 0.0 [5..858] [2..872]
IMB1_RAT - Importin subunit beta-1 OS=Rattus norvegicus GN=Kpnb1 PE=1 SV=1
 0.0 [5..858] [2..871]
IMB1_SCHPO - Importin subunit beta-1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=kap95 PE=3 SV=1
kap95 - karyopherin Kap95
 0.0 [10..858] [6..860]
FBpp0294038, FBp... - The gene Female sterile (2) Ketel is referred to in FlyBase by the symbol Dmel\Fs(2)Ket (CG2637, FBg...
 0.0 [5..857] [8..876]
IMB1_ARATH - Importin subunit beta-1 OS=Arabidopsis thaliana GN=KPNB1 PE=1 SV=1
 0.0 [5..861] [4..870]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
 0.0 [5..858] [2..842]
gi|115489162, gi... - gi|3983665|dbj|BAA34862.1| importin-beta2 [Oryza sativa Japonica Group], gi|125579771|gb|EAZ20917.1|...
 0.0 [3..860] [2..871]
gi|18029287, gi|... - gi|18029287|gb|AAL56465.1| importin beta-like protein [Oikopleura dioica], gi|172087236|ref|XP_00191...
 0.0 [8..857] [3..877]

Back

Predicted Domain #1
Region A:
Residues: [1-248] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTAEFAQLL ENSILSPDQN IRLTSETQLK KLSNDNFLQF AGLSSQVLID ENTKLEGRIL  60
   61 AALTLKNELV SKDSVKTQQF AQRWITQVSP EAKNQIKTNA LTALVSIEPR IANAAAQLIA 120
  121 AIADIELPHG AWPELMKIMV DNTGAEQPEN VKRASLLALG YMCESADPQS QALVSSSNNI 180
  181 LIAIVQGAQS TETSKAVRLA ALNALADSLI FIKNNMEREG ERNYLMQVVC EATQAEDIEV 240
  241 QAAAFGCL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1397.0
Match: 1qgkA_
Description: Importin beta
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein transporter activity 4.58709163830613 bayes_pls_golite062009
binding 3.0667965351474 bayes_pls_golite062009
protein transmembrane transporter activity 2.74547353635661 bayes_pls_golite062009
transporter activity 2.48700774379895 bayes_pls_golite062009
nucleic acid binding 2.34284977509828 bayes_pls_golite062009
substrate-specific transporter activity 2.26725422172281 bayes_pls_golite062009
nuclear export signal receptor activity 2.13470398426489 bayes_pls_golite062009
nuclear localization sequence binding 1.91487015967262 bayes_pls_golite062009
transcription regulator activity 1.76231475025891 bayes_pls_golite062009
protein binding 1.73688475473996 bayes_pls_golite062009
DNA binding 1.62032607987786 bayes_pls_golite062009
transmembrane transporter activity 1.28481004323799 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 1.09652988954158 bayes_pls_golite062009
transcription factor activity 0.923253759652909 bayes_pls_golite062009
structural molecule activity 0.908029258648777 bayes_pls_golite062009
translation initiation factor activity 0.83079633551839 bayes_pls_golite062009
translation regulator activity 0.82193201542158 bayes_pls_golite062009
translation factor activity, nucleic acid binding 0.803700928110921 bayes_pls_golite062009
cytoskeletal protein binding 0.773975545005505 bayes_pls_golite062009
signal transducer activity 0.662662274021266 bayes_pls_golite062009
molecular transducer activity 0.662662274021266 bayes_pls_golite062009
actin binding 0.572473732371314 bayes_pls_golite062009
signal sequence binding 0.57106697498903 bayes_pls_golite062009
mRNA binding 0.46864854653143 bayes_pls_golite062009
RNA binding 0.40024158562931 bayes_pls_golite062009
active transmembrane transporter activity 0.252495966234234 bayes_pls_golite062009
ion transmembrane transporter activity 0.248585912061178 bayes_pls_golite062009
primary active transmembrane transporter activity 0.226380819487924 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 0.217517113570989 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 0.178770060806735 bayes_pls_golite062009
ATPase activity, coupled to movement of substances 0.175241020572885 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances 0.174922130116569 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.100181463251306 bayes_pls_golite062009
pyrophosphatase activity 0.0635404099346928 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.0548082069333885 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.052195223119721 bayes_pls_golite062009
cation transmembrane transporter activity 0.0405268469927988 bayes_pls_golite062009
transcription activator activity 0.0232727461674547 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [249-442] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CKIMSLYYTF MKPYMEQALY ALTIATMKSP NDKVASMTVE FWSTICEEEI DIAYELAQFP  60
   61 QSPLQSYNFA LSSIKDVVPN LLNLLTRQNE DPEDDDWNVS MSAGACLQLF AQNCGNHILE 120
  121 PVLEFVEQNI TADNWRNREA AVMAFGSIMD GPDKVQRTYY VHQALPSILN LMNDQSLQVK 180
  181 ETTAWCIGRI ADSV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1397.0
Match: 1qgkA_
Description: Importin beta
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [443-541] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AESIDPQQHL PGVVQACLIG LQDHPKVATN CSWTIINLVE QLAEATPSPI YNFYPALVDG  60
   61 LIGAANRIDN EFNARASAFS ALTTMVEYAT DTVAETSAS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1397.0
Match: 1qgkA_
Description: Importin beta
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [542-648] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ISTFVMDKLG QTMSVDENQL TLEDAQSLQE LQSNILTVLA AVIRKSPSSV EPVADMLMGL  60
   61 FFRLLEKKDS AFIEDDVFYA ISALAASLGK GFEKYLETFS PYLLKAL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1397.0
Match: 1qgkA_
Description: Importin beta
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [649-861] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NQVDSPVSIT AVGFIADISN SLEEDFRRYS DAMMNVLAQM ISNPNARREL KPAVLSVFGD  60
   61 IASNIGADFI PYLNDIMALC VAAQNTKPEN GTLEALDYQI KVLEAVLDAY VGIVAGLHDK 120
  121 PEALFPYVGT IFQFIAQVAE DPQLYSEDAT SRAAVGLIGD IAAMFPDGSI KQFYGQDWVI 180
  181 DYIKRTRSGQ LFSQATKDTA RWAREQQKRQ LSL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1397.0
Match: 1qgkA_
Description: Importin beta
Matching Structure (courtesy of the PDB):
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle