| Protein: | HIR2_YEAST |
| Organism: | Saccharomyces cerevisiae S288c |
| Length: | 875 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HIR2_YEAST.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [67..750] | [865..1491] |
|
|
0.0 | [1..875] | [1..875] |
|
Region A: Residues: [1-85] |
1 11 21 31 41 51
| | | | | |
1 MRLLKYPLDI HNEQVNALAA LGPYIILAGS GGHVMAWRQQ QLVDTAFDRV MIKDLKPEVS 60
61 FQVDQDTTGD IFFITGDLET LYIGS
|
| Detection Method: |  |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
| Term | Confidence | Notes |
| general RNA polymerase II transcription factor activity | 2.79445416141967 | bayes_pls_golite062009 |
| binding | 2.42570478946173 | bayes_pls_golite062009 |
| transcription regulator activity | 2.3610959773142 | bayes_pls_golite062009 |
| nucleic acid binding | 2.30918780727915 | bayes_pls_golite062009 |
| transcription repressor activity | 2.29049708962212 | bayes_pls_golite062009 |
| DNA binding | 1.71685536470455 | bayes_pls_golite062009 |
| transcription corepressor activity | 1.41752877005447 | bayes_pls_golite062009 |
| protein binding | 1.21879977456466 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 1.19593750149343 | bayes_pls_golite062009 |
| transcription factor activity | 1.08768505897883 | bayes_pls_golite062009 |
| 0.88172763425403 | bayes_pls_golite062009 | |
| histone binding | 0.685319917508843 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 0.676924760416604 | bayes_pls_golite062009 |
| actin binding | 0.529861581509437 | bayes_pls_golite062009 |
| transcription factor binding | 0.489473003915035 | bayes_pls_golite062009 |
| snoRNA binding | 0.347797037104681 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.30761651528651 | bayes_pls_golite062009 |
| transporter activity | 0.284701931503833 | bayes_pls_golite062009 |
| DNA-dependent ATPase activity | 0.164101908612691 | bayes_pls_golite062009 |
| chromatin binding | 0.151977098745772 | bayes_pls_golite062009 |
| structural molecule activity | 0.0936365746095786 | bayes_pls_golite062009 |
|
Region A: Residues: [86-473] |
1 11 21 31 41 51
| | | | | |
1 EHRLWGYSGW LCRDTNNINS VEKMNSKLLF ECKSPSTITD VKYDINLGIL FVLLSNENKI 60
61 LLFRHKTFDK LSEITIDKAS KPITGIIDPT GQTFTVMTSD RSILVYQINK TGTHKLINKL 120
121 TQHVQMYPLH YRISMSPQAD ILPVINSVKG VPNNATSCTA LLDRNNNYKV TKTLVTPSSN 180
181 GCRVLVYSPA FYEKPNLKKG TSTRYNLIAT SGSTDGTILV WNTKRMKPLF NALQVSSTAI 240
241 NDMSWSQDGF TLFAISNDAT LYTFAFQEKD LGVALPQTEI KSLQEVNKKL PKLEEPLAEQ 300
301 IPKSFPENIK LEESASAAPI PNDIGRSAVG KKPTKKKTAN NQTNGIKTIQ STSMEFNTPS 360
361 YTVPRDLKRK PKEATPSNIA PGSKKQKK
|
| Detection Method: | |
| Confidence: | 70.39794 |
| Match: | 1gg2B_ |
| Description: | beta1-subunit of the signal-transducing G protein heterotrimer |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription regulator activity | 5.23858959608048 | bayes_pls_golite062009 |
| DNA binding | 4.78517210147551 | bayes_pls_golite062009 |
| nucleic acid binding | 4.72059012764202 | bayes_pls_golite062009 |
| transcription factor activity | 4.02736190679869 | bayes_pls_golite062009 |
| transcription repressor activity | 3.60278632732466 | bayes_pls_golite062009 |
| binding | 3.37660003833383 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 2.84400558797599 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 2.41045867230388 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 2.21432668306508 | bayes_pls_golite062009 |
| transcription activator activity | 2.13702350917359 | bayes_pls_golite062009 |
| transcription elongation regulator activity | 1.75305601393584 | bayes_pls_golite062009 |
| structure-specific DNA binding | 0.795220428630727 | bayes_pls_golite062009 |
| transcription factor binding | 0.752335897765285 | bayes_pls_golite062009 |
| protein binding | 0.726445167461826 | bayes_pls_golite062009 |
| specific transcriptional repressor activity | 0.710995647413393 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 0.490809930581315 | bayes_pls_golite062009 |
| transcription corepressor activity | 0.252392400929265 | bayes_pls_golite062009 |
| DNA-dependent ATPase activity | 0.224230323813474 | bayes_pls_golite062009 |
| structural molecule activity | 0.128347187436068 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity, enhancer binding | 0.0406721670764369 | bayes_pls_golite062009 |
|
Region A: Residues: [474-698] |
1 11 21 31 41 51
| | | | | |
1 ELQPIDFLDT GLLLPNTSFS RIRLATPKIR STFKYSPINN PNLILDVKNG SGNEQRPTIV 60
61 KLTSKVLDQD QVLFQDFIPK LITICTAGDT FWSFCSEDGS IYIYSDSGRK LMAPLVLGVS 120
121 ISFLEACGTY LLCLTSIGEL YCWNIEQKKL AFPTNTIYPL LNPSLRYSDD ILTRAENITL 180
181 CSITKKGVPL VTLSNGDGYL FDKNMETWLL VSDGWWAYGS QYWDT
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [699-752] |
1 11 21 31 41 51
| | | | | |
1 TNTTGLSSSK ANTDSFNGSE SNINEIVSDI KNDNQSIINF LECKTNDELN RKGR
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [753-875] |
1 11 21 31 41 51
| | | | | |
1 IKNLQRFART ILMKEGFENM EEIVTLSHLE NKILISIRLE EPEEFSKLMM VYCIRLSELG 60
61 YMDRLNDVFQ WLYDDLPISG TGSAFADKDF KRNLLKKILI ACGDIRQVQR VTTRYAKEMN 120
121 IIS
|
| Detection Method: | |
| Confidence: | 7.63 |
| Match: | 1bgxT |
| Description: | 5' to 3' exonuclease domain of DNA polymerase Taq; Exonuclease domain of prokaryotic DNA polymerase; DNA polymerase I (Klenow fragment) |
Matching Structure (courtesy of the PDB): |
|
