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Protein Overview: HIR2_YEAST

General Information:
Name(s) found: HIR2_YEAST [Swiss-Prot]
Description(s) found:
  • Protein HIR2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HIR2 PE=1 SV=2 [Swiss-Prot]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 875 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRLLKYPLDI HNEQVNALAA LGPYIILAGS GGHVMAWRQQ QLVDTAFDRV MIKDLKPEVS  60
   61 FQVDQDTTGD IFFITGDLET LYIGSEHRLW GYSGWLCRDT NNINSVEKMN SKLLFECKSP 120
  121 STITDVKYDI NLGILFVLLS NENKILLFRH KTFDKLSEIT IDKASKPITG IIDPTGQTFT 180
  181 VMTSDRSILV YQINKTGTHK LINKLTQHVQ MYPLHYRISM SPQADILPVI NSVKGVPNNA 240
  241 TSCTALLDRN NNYKVTKTLV TPSSNGCRVL VYSPAFYEKP NLKKGTSTRY NLIATSGSTD 300
  301 GTILVWNTKR MKPLFNALQV SSTAINDMSW SQDGFTLFAI SNDATLYTFA FQEKDLGVAL 360
  361 PQTEIKSLQE VNKKLPKLEE PLAEQIPKSF PENIKLEESA SAAPIPNDIG RSAVGKKPTK 420
  421 KKTANNQTNG IKTIQSTSME FNTPSYTVPR DLKRKPKEAT PSNIAPGSKK QKKELQPIDF 480
  481 LDTGLLLPNT SFSRIRLATP KIRSTFKYSP INNPNLILDV KNGSGNEQRP TIVKLTSKVL 540
  541 DQDQVLFQDF IPKLITICTA GDTFWSFCSE DGSIYIYSDS GRKLMAPLVL GVSISFLEAC 600
  601 GTYLLCLTSI GELYCWNIEQ KKLAFPTNTI YPLLNPSLRY SDDILTRAEN ITLCSITKKG 660
  661 VPLVTLSNGD GYLFDKNMET WLLVSDGWWA YGSQYWDTTN TTGLSSSKAN TDSFNGSESN 720
  721 INEIVSDIKN DNQSIINFLE CKTNDELNRK GRIKNLQRFA RTILMKEGFE NMEEIVTLSH 780
  781 LENKILISIR LEEPEEFSKL MMVYCIRLSE LGYMDRLNDV FQWLYDDLPI SGTGSAFADK 840
  841 DFKRNLLKKI LIACGDIRQV QRVTTRYAKE MNIIS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..85] MSA 1.652995 View MSA. No confident structure predictions are available.
    2 View Details [86..473] PSI-BLAST 70.39794 beta1-subunit of the signal-transducing G protein heterotrimer
    3 View Details [474..698] MSA 23.515997 View MSA. No confident structure predictions are available.
    4 View Details [699..752] deduced N/A No confident structure predictions are available.
    5 View Details [753..875] ORFEUS 7.63 5' to 3' exonuclease domain of DNA polymerase Taq; Exonuclease domain of prokaryotic DNA polymerase; DNA polymerase I (Klenow fragment)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • general RNA polymerase II transcription factor activity
    		•  2.79445416141967 bayes_pls_golite062009
  • binding
    		•  2.42570478946173 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.3610959773142 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.30918780727915 bayes_pls_golite062009
  • transcription repressor activity
    		•  2.29049708962212 bayes_pls_golite062009
  • DNA binding
    		•  1.71685536470455 bayes_pls_golite062009
  • transcription corepressor activity
    		•  1.41752877005447 bayes_pls_golite062009
  • protein binding
    		•  1.21879977456466 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.19593750149343 bayes_pls_golite062009
  • transcription factor activity
    		•  1.08768505897883 bayes_pls_golite062009
    		• 0.88172763425403 bayes_pls_golite062009
  • histone binding
    		•  0.685319917508843 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.676924760416604 bayes_pls_golite062009
  • actin binding
    		•  0.529861581509437 bayes_pls_golite062009
  • transcription factor binding
    		•  0.489473003915035 bayes_pls_golite062009
  • snoRNA binding
    		•  0.347797037104681 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.30761651528651 bayes_pls_golite062009
  • transporter activity
    		•  0.284701931503833 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  0.164101908612691 bayes_pls_golite062009
  • chromatin binding
    		•  0.151977098745772 bayes_pls_golite062009
  • structural molecule activity
    		•  0.0936365746095786 bayes_pls_golite062009
    2
    Term Confidence Notes
  • transcription regulator activity
    		•  5.23858959608048 bayes_pls_golite062009
  • DNA binding
    		•  4.78517210147551 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.72059012764202 bayes_pls_golite062009
  • transcription factor activity
    		•  4.02736190679869 bayes_pls_golite062009
  • transcription repressor activity
    		•  3.60278632732466 bayes_pls_golite062009
  • binding
    		•  3.37660003833383 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  2.84400558797599 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  2.41045867230388 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  2.21432668306508 bayes_pls_golite062009
  • transcription activator activity
    		•  2.13702350917359 bayes_pls_golite062009
  • transcription elongation regulator activity
    		•  1.75305601393584 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.795220428630727 bayes_pls_golite062009
  • transcription factor binding
    		•  0.752335897765285 bayes_pls_golite062009
  • protein binding
    		•  0.726445167461826 bayes_pls_golite062009
  • specific transcriptional repressor activity
    		•  0.710995647413393 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  0.490809930581315 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.252392400929265 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  0.224230323813474 bayes_pls_golite062009
  • structural molecule activity
    		•  0.128347187436068 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity, enhancer binding
    		•  0.0406721670764369 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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