YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: Ada2b-PB
Organism: Drosophila melanogaster
Length: 555 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Ada2b-PB.

Description E-value Query
Range		 Subject
Range
gi|39940282, gi|... - gi|39940282|ref|XP_359678.1| hypothetical protein MGG_05099 [Magnaporthe grisea 70-15], gb|EAA52407....
 263.0 [0..2] [555..10]

Back

Predicted Domain #1
Region A:
Residues: [1-63] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTIADLFTK YNCTNCQDDI QGIRVHCAEC ENFDLCLQCF AAGAEIGAHQ NNHSYQFMDT  60
   61 GTS

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.87
Match: 2e5rA
Description: No description for 2e5rA was found.

Predicted Domain #2
Region A:
Residues: [64-178] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ILSVFRGKGA WTAREEIRLL DAIEQYGFGN WEDISKHIET KSAEDAKEEY VNKFVNGTIG  60
   61 RATWTPAQSQ RPRLIDHTGD DDAGPLGTNA LSTLPPLEIN SDEAMQLGYM PNRDS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 23.221849
Match: 1h88C
Description: c-Myb, DNA-binding domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
histone acetyltransferase activity 5.80609397811031 bayes_pls_golite062009
lysine N-acetyltransferase activity 5.80609397811031 bayes_pls_golite062009
transcription regulator activity 5.13863038737912 bayes_pls_golite062009
DNA binding 4.66369707598026 bayes_pls_golite062009
N-acyltransferase activity 4.57418118498868 bayes_pls_golite062009
N-acetyltransferase activity 4.37954729923498 bayes_pls_golite062009
nucleic acid binding 4.20953772435302 bayes_pls_golite062009
transcription factor activity 4.06706589695599 bayes_pls_golite062009
acetyltransferase activity 3.80908511328212 bayes_pls_golite062009
acyltransferase activity 3.35206890637362 bayes_pls_golite062009
transferase activity, transferring acyl groups other than amino-acyl groups 3.30532537006075 bayes_pls_golite062009
transferase activity, transferring acyl groups 3.08442186629685 bayes_pls_golite062009
binding 3.02779747447702 bayes_pls_golite062009
sequence-specific DNA binding 2.41271657675151 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.26183812259792 bayes_pls_golite062009
transcription repressor activity 1.91962622287073 bayes_pls_golite062009
protein binding 1.88087411289001 bayes_pls_golite062009
transcription activator activity 1.77700860354597 bayes_pls_golite062009
transcription factor binding 1.40653841901929 bayes_pls_golite062009
protein deacetylase activity 1.23680480131205 bayes_pls_golite062009
histone deacetylase activity 1.18932416576802 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 1.14886080629275 bayes_pls_golite062009
chromatin binding 0.876241359231159 bayes_pls_golite062009
transcription cofactor activity 0.84983974758882 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.663171909351326 bayes_pls_golite062009
histone binding 0.557787598121402 bayes_pls_golite062009
deacetylase activity 0.530687254192222 bayes_pls_golite062009
transcription coactivator activity 0.2679415219517 bayes_pls_golite062009
transcription corepressor activity 0.25931464844298 bayes_pls_golite062009
cytoskeletal protein binding 0.236060274498333 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.141400887946529 bayes_pls_golite062009
telomeric DNA binding 0.0735027998484772 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [179-354] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FEREYDPTAE QLISNISLSS EDTEVDVMLK LAHVDIYTRR LRERARRKRM VRDYQLVSNF  60
   61 FRNRNYAQQQ GLTKEQREFR DRFRVYAQFY TCNEYERLLG SLEREKELRI RQSELYRYRY 120
  121 NGLTKIAECT HFEQHAATAT HRSTGPYGHG KTDHTHTSNG SHRPPSSSLH SPQPNL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [355-477] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RKVEMSSGGE ASSNSIAPRN TLHIADPTCS GALLPSKNYL DSCRGSSAAT MLQTTGMVMG  60
   61 VTVDSGATTG VTSTATTMAN LPTNSAKGSQ QHLQPLQQHP QLLQSGNQHK MQNEAAGGGS 120
  121 DQV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [478-555] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSMSLKLRTQ LEELKHLPQP PGSELLSHNE LDLCKKHNIT PTTYLSVKTV CLSGAPSLGS  60
   61 PMETSLRKFF IKCGWLSH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 15.0
Match: 2aqeA
Description: Structural and functional analysis of ada2 alpha swirm domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
histone acetyltransferase activity 5.80609397811031 bayes_pls_golite062009
lysine N-acetyltransferase activity 5.80609397811031 bayes_pls_golite062009
transcription regulator activity 5.13863038737912 bayes_pls_golite062009
DNA binding 4.66369707598026 bayes_pls_golite062009
N-acyltransferase activity 4.57418118498868 bayes_pls_golite062009
N-acetyltransferase activity 4.37954729923498 bayes_pls_golite062009
nucleic acid binding 4.20953772435302 bayes_pls_golite062009
transcription factor activity 4.06706589695599 bayes_pls_golite062009
acetyltransferase activity 3.80908511328212 bayes_pls_golite062009
acyltransferase activity 3.35206890637362 bayes_pls_golite062009
transferase activity, transferring acyl groups other than amino-acyl groups 3.30532537006075 bayes_pls_golite062009
transferase activity, transferring acyl groups 3.08442186629685 bayes_pls_golite062009
binding 3.02779747447702 bayes_pls_golite062009
sequence-specific DNA binding 2.41271657675151 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.26183812259792 bayes_pls_golite062009
transcription repressor activity 1.91962622287073 bayes_pls_golite062009
protein binding 1.88087411289001 bayes_pls_golite062009
transcription activator activity 1.77700860354597 bayes_pls_golite062009
transcription factor binding 1.40653841901929 bayes_pls_golite062009
protein deacetylase activity 1.23680480131205 bayes_pls_golite062009
histone deacetylase activity 1.18932416576802 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 1.14886080629275 bayes_pls_golite062009
chromatin binding 0.876241359231159 bayes_pls_golite062009
transcription cofactor activity 0.84983974758882 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.663171909351326 bayes_pls_golite062009
histone binding 0.557787598121402 bayes_pls_golite062009
deacetylase activity 0.530687254192222 bayes_pls_golite062009
transcription coactivator activity 0.2679415219517 bayes_pls_golite062009
transcription corepressor activity 0.25931464844298 bayes_pls_golite062009
cytoskeletal protein binding 0.236060274498333 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.141400887946529 bayes_pls_golite062009
telomeric DNA binding 0.0735027998484772 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle