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View Structure Prediction Details

Protein: RFC3_ARATH
Organism: Arabidopsis thaliana
Length: 354 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RFC3_ARATH.

Description E-value Query
Range
Subject
Range
gi|86148367, gi|... - gi|86148367|ref|ZP_01066660.1| DNA polymerase III subunits gamma and tau [Vibrio sp. MED222], gi|858...
244.0 [0..1] [339..4]

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Predicted Domain #1
Region A:
Residues: [1-354]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLWVDKYRPK SLDKVIVHED IAQKLKKLVS EQDCPHLLFY GPSGSGKKTL IMALLKQIYG  60
   61 ASAEKVKVEN RAWKVDAGSR TIDLELTTLS STNHVELTPS DAGFQDRYIV QEIIKEMAKN 120
  121 RPIDTKGKKG YKVLVLNEVD KLSREAQHSL RRTMEKYSSS CRLILCCNSS SKVTEAIKSR 180
  181 CLNVRINAPS QEEIVKVLEF VAKKESLQLP QGFAARIAEK SNRSLRRAIL SLETCRVQNY 240
  241 PFTGNQVISP MDWEEYVAEI ATDMMKEQSP KKLFQVRGKV YELLVNCIPP EVILKRLLHE 300
  301 LLKKLDSELK LEVCHWAAYY EHRMRLGQKA IFHIEAFVAK FMSIYKNFLI STFG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 44.69897
Match: 1sxjE
Description: Crystal Structure of the Eukaryotic Clamp Loader (Replication Factor C, RFC) Bound to the DNA Sliding Clamp (Proliferating Cell Nuclear Antigen, PCNA)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
DNA clamp loader activity 6.51495346697904 bayes_pls_golite062009
protein-DNA loading ATPase activity 6.40748863504898 bayes_pls_golite062009
mismatched DNA binding 2.51625633651862 bayes_pls_golite062009
DNA helicase activity 2.2817164193758 bayes_pls_golite062009
pyrophosphatase activity 2.23646936731119 bayes_pls_golite062009
ATP-dependent DNA helicase activity 1.88455339138556 bayes_pls_golite062009
1.85506769032946 bayes_pls_golite062009
helicase activity 1.70242731830224 bayes_pls_golite062009
guanine/thymine mispair binding 1.69026972999845 bayes_pls_golite062009
DNA insertion or deletion binding 1.68890613599528 bayes_pls_golite062009
binding 1.62860302498201 bayes_pls_golite062009
DNA replication origin binding 1.62491387774159 bayes_pls_golite062009
nucleic acid binding 1.49633029954726 bayes_pls_golite062009
catalytic activity 1.32370671504792 bayes_pls_golite062009
structure-specific DNA binding 1.2539059700735 bayes_pls_golite062009
DNA-dependent ATPase activity 1.2537888487362 bayes_pls_golite062009
purine NTP-dependent helicase activity 1.19311444180077 bayes_pls_golite062009
ATP-dependent helicase activity 1.19311444180077 bayes_pls_golite062009
motor activity 1.14667913749579 bayes_pls_golite062009
microtubule motor activity 1.1277447806079 bayes_pls_golite062009
double-stranded DNA binding 1.117585097627 bayes_pls_golite062009
DNA-directed DNA polymerase activity 0.971476020912368 bayes_pls_golite062009
DNA binding 0.967303417236485 bayes_pls_golite062009
DNA polymerase activity 0.928091843881235 bayes_pls_golite062009
transcription regulator activity 0.748437190903548 bayes_pls_golite062009
single base insertion or deletion binding 0.629563765934841 bayes_pls_golite062009
single-stranded DNA binding 0.568457189190858 bayes_pls_golite062009
cytoskeletal protein binding 0.500462538667228 bayes_pls_golite062009
protein binding 0.324679002546113 bayes_pls_golite062009
DNA strand annealing activity 0.283577486331079 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.248432446853676 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.217252531553173 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.215962398124297 bayes_pls_golite062009
structural constituent of ribosome 0.089234257580272 bayes_pls_golite062009
3'-5' DNA helicase activity 0.0769112340058804 bayes_pls_golite062009
ATPase activity 0.0740243885501273 bayes_pls_golite062009
lysine N-acetyltransferase activity 0.0320943071400439 bayes_pls_golite062009
histone acetyltransferase activity 0.0320943071400439 bayes_pls_golite062009
double-strand/single-strand DNA junction binding 0.0136229525922795 bayes_pls_golite062009
actin binding 0.00482938540552702 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle