| Protein: | gi|190404649 |
| Organism: | Saccharomyces cerevisiae RM11-1a |
| Length: | 632 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|190404649.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..632] | [1..632] |
|
|
0.0 | [24..624] | [7..563] |
|
|
0.0 | [23..615] | [6..549] |
|
Region A: Residues: [1-33] |
1 11 21 31 41 51
| | | | | |
1 MSKFTWKELI QLGSPSKAYE SSLACIAHID MNA
|
|
Region B: Residues: [122-299] |
1 11 21 31 41 51
| | | | | |
1 EDHKVSLEPY RRESRKALKI FKSACDLVER ASIDEVFLDL GRICFNMLMF DNEYELTGDL 60
61 KLKDALSNIR EAFIGGNYDI NSHLPLIPEK IKSLKFEGDV FNPEGRDLIT DWDDVILALG 120
121 SQVCKGIRDS IKDILGYTTS CGLSSTKNVC KLASNYKKPD AQTIVKNDCL LDFLDCGK
|
| Detection Method: |  |
| Confidence: | 10119.0 |
| Match: | 1jihA_ |
| Description: | DNA polymerase eta |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| DNA-directed DNA polymerase activity | 8.5725258398851 | bayes_pls_golite062009 |
| DNA polymerase activity | 8.52309706572764 | bayes_pls_golite062009 |
| nucleotidyltransferase activity | 6.34496739872612 | bayes_pls_golite062009 |
| DNA primase activity | 5.34779288251618 | bayes_pls_golite062009 |
| chromatin binding | 2.18085270555452 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 1.74380808085854 | bayes_pls_golite062009 |
| DNA binding | 1.69096430884207 | bayes_pls_golite062009 |
| nucleic acid binding | 1.57540655259696 | bayes_pls_golite062009 |
| binding | 1.40175931463327 | bayes_pls_golite062009 |
| structure-specific DNA binding | 1.06010018021303 | bayes_pls_golite062009 |
| catalytic activity | 1.04899053677564 | bayes_pls_golite062009 |
| DNA-directed RNA polymerase activity | 0.83818211151495 | bayes_pls_golite062009 |
| RNA polymerase activity | 0.83818211151495 | bayes_pls_golite062009 |
| transferase activity | 0.784455099927681 | bayes_pls_golite062009 |
| exonuclease activity | 0.778608024896469 | bayes_pls_golite062009 |
| damaged DNA binding | 0.39441061793492 | bayes_pls_golite062009 |
| protein binding | 0.354190470641287 | bayes_pls_golite062009 |
| 3'-5' exonuclease activity | 0.0700154911930899 | bayes_pls_golite062009 |
|
Region A: Residues: [34-121] |
1 11 21 31 41 51
| | | | | |
1 FFAQVEQMRC GLSKEDPVVC VQWNSIIAVS YAARKYGISR MDTIQEALKK CSNLIPIHTA 60
61 VFKKGEDFWQ YHDGCGSWVQ DPAKQISV
|
|
Region B: Residues: [300-388] |
1 11 21 31 41 51
| | | | | |
1 FEITSFWTLG GVLGKELIDV LDLPHENSIK HIRETWPDNA GQLKEFLDAK VKQSDYDRST 60
61 SNIDPLKTAD LAEKLFKLSR GRYGLPLSS
|
| Detection Method: | |
| Confidence: | 10119.0 |
| Match: | 1jihA_ |
| Description: | DNA polymerase eta |
| Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription regulator activity | 3.3375695352073 | bayes_pls_golite062009 |
| DNA binding | 3.28852346568913 | bayes_pls_golite062009 |
| nucleic acid binding | 3.28464324017293 | bayes_pls_golite062009 |
| binding | 2.56809202445862 | bayes_pls_golite062009 |
| structure-specific DNA binding | 2.42858975345257 | bayes_pls_golite062009 |
| transcription factor activity | 2.32991522163341 | bayes_pls_golite062009 |
| chromatin binding | 2.32872787634324 | bayes_pls_golite062009 |
| transcription activator activity | 1.20800295439208 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 1.14039305317011 | bayes_pls_golite062009 |
| protein binding | 0.952480850696098 | bayes_pls_golite062009 |
| double-stranded DNA binding | 0.752135837564561 | bayes_pls_golite062009 |
| transcription repressor activity | 0.733541244206639 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 0.564341752288536 | bayes_pls_golite062009 |
| transcription factor binding | 0.547857728784058 | bayes_pls_golite062009 |
| catalytic activity | 0.263007611601737 | bayes_pls_golite062009 |
|
Region A: Residues: [389-530] |
1 11 21 31 41 51
| | | | | |
1 RPVVKSMMSN KNLRGKSCNS IVDCISWLEV FCAELTSRIQ DLEQEYNKIV IPRTVSISLK 60
61 TKSYEVYRKS GPVAYKGINF QSHELLKVGI KFVTDLDIKG KNKSYYPLTK LSMTITNFDI 120
121 IDLQKTVVDM FGNQVHTFKS SA
|
| Detection Method: | |
| Confidence: | 10119.0 |
| Match: | 1jihA_ |
| Description: | DNA polymerase eta |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [531-632] |
1 11 21 31 41 51
| | | | | |
1 GKEDEEKTTS SKADEKTPKL ECCKYQVTFT DQKALQEHAD YHLALKLSEG LNGAEESSKN 60
61 LSFGEKRLLF SRKRPNSQHT ATPQKKQVTS SKNILSFFTR KK
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.472 | a.118.1 | ARM repeat |
| View | Download | 0.444 | a.74.1 | Cyclin-like |
| View | Download | 0.476 | a.73.1 | Retrovirus capsid protein, N-terminal core domain |
| View | Download | 0.624 | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.513 | a.46.1 | Methionine synthase domain |
| View | Download | 0.441 | a.47.2 | t-snare proteins |
| View | Download | 0.404 | d.129.2 | Phosphoglucomutase, C-terminal domain |
| View | Download | 0.383 | a.61.1 | Retroviral matrix proteins |
| View | Download | 0.366 | a.7.2 | Enzyme IIa from lactose specific PTS, IIa-lac |
| View | Download | 0.358 | a.24.11 | Bacterial GAP domain |
| View | Download | 0.350 | a.8.2 | Plasmid maintenance system epsilon/zeta, antidote epsilon subunit |
| View | Download | 0.328 | a.151.1 | Glutamyl tRNA-reductase dimerization domain |
| View | Download | 0.326 | a.1.1 | Globin-like |
| View | Download | 0.315 | a.77.1 | DEATH domain |
| View | Download | 0.304 | a.24.7 | FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) |
| View | Download | 0.297 | a.2.11 | Fe,Mn superoxide dismutase (SOD), N-terminal domain |
| View | Download | 0.279 | a.90.1 | Transcription factor STAT-4 N-domain |
| View | Download | 0.273 | a.24.4 | Hemerythrin |
| View | Download | 0.260 | a.7.1 | Spectrin repeat |
| View | Download | 0.254 | a.26.1 | 4-helical cytokines |
| View | Download | 0.243 | d.57.1 | DNA damage-inducible protein DinI |
| View | Download | 0.239 | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.236 | i.1.1 | Ribosome and ribosomal fragments |
| View | Download | 0.219 | d.58.39 | Glutamyl tRNA-reductase catalytic, N-terminal domain |
| View | Download | 0.216 | d.13.1 | HIT-like |
| View | Download | 0.207 | a.4.6 | C-terminal effector domain of the bipartite response regulators |
