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View Structure Prediction Details

Protein: CDPKY_ARATH
Organism: Arabidopsis thaliana
Length: 523 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CDPKY_ARATH.

Description E-value Query
Range
Subject
Range
CDPKH_ARATH - Calcium-dependent protein kinase 17 OS=Arabidopsis thaliana GN=CPK17 PE=2 SV=1
460.0 [0..1] [523..1]

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Predicted Domain #1
Region A:
Residues: [1-107]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGNCCSHGRD SDDNKEEPRP ENGGGGVGAA EASVRASKHP PASPPPATKQ GPIGPVLGRP  60
   61 MEDVKSSYTL GKELGRGQFG VTHLCTQKAT GLQFACKTIA KRKLVNK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 72.09691
Match: 2jc6A
Description: No description for 2jc6A was found.

Predicted Domain #2
Region A:
Residues: [108-381]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EDIEDVRREV QIMHHLTGQP NIVELKGAYE DKHSVHLVME LCAGGELFDR IIAKGHYSER  60
   61 AAASLLRTIV QIIHTCHSMG VIHRDLKPEN FLLLSKDENS PLKATDFGLS VFYKPGEVFK 120
  121 DIVGSAYYIA PEVLRRKYGP EADIWSIGVM LYILLCGVPP FWAESENGIF NAILSGQVDF 180
  181 SSDPWPVISP QAKDLVRKML NSDPKQRLTA AQVLNHPWIK EDGEAPDVPL DNAVMSRLKQ 240
  241 FKAMNNFKKV ALRVIAGCLS EEEIMGLKEM FKGM

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 10.1
Match: 1a06A
Description: CALMODULIN-DEPENDENT PROTEIN KINASE FROM RAT
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
phosphotransferase activity, alcohol group as acceptor 5.1266532460433 bayes_pls_golite062009
protein kinase activity 5.06553613807469 bayes_pls_golite062009
kinase activity 4.97217471277362 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 4.63130611618105 bayes_pls_golite062009
protein serine/threonine kinase activity 4.09005206351126 bayes_pls_golite062009
calmodulin-dependent protein kinase activity 4.05234521173026 bayes_pls_golite062009
transferase activity 3.71864228364346 bayes_pls_golite062009
binding 2.67450299947447 bayes_pls_golite062009
protein binding 2.2016624288568 bayes_pls_golite062009
tubulin binding 2.17977514833097 bayes_pls_golite062009
cytoskeletal protein binding 2.13652345199607 bayes_pls_golite062009
microtubule binding 1.88775178436595 bayes_pls_golite062009
ATP binding 1.74734232320398 bayes_pls_golite062009
adenyl ribonucleotide binding 1.71077512212789 bayes_pls_golite062009
adenyl nucleotide binding 1.68781845572802 bayes_pls_golite062009
transcription regulator activity 1.65136036852775 bayes_pls_golite062009
nucleic acid binding 1.54238193255857 bayes_pls_golite062009
purine ribonucleotide binding 1.45955619008784 bayes_pls_golite062009
ribonucleotide binding 1.45954404692843 bayes_pls_golite062009
purine nucleotide binding 1.44332631201954 bayes_pls_golite062009
nucleotide binding 1.43931752337662 bayes_pls_golite062009
DNA binding 1.4225378476001 bayes_pls_golite062009
insulin receptor substrate binding 1.38590736769351 bayes_pls_golite062009
actin binding 1.35764678903023 bayes_pls_golite062009
gamma-tubulin binding 1.22971419017172 bayes_pls_golite062009
catalytic activity 1.13659909751975 bayes_pls_golite062009
transcription factor activity 1.12734691449801 bayes_pls_golite062009
protein tyrosine kinase activity 1.07654572354135 bayes_pls_golite062009
receptor signaling protein serine/threonine kinase activity 1.06242930071592 bayes_pls_golite062009
transcription activator activity 1.02847225770561 bayes_pls_golite062009
receptor signaling protein activity 0.989242693203213 bayes_pls_golite062009
transporter activity 0.580496499590986 bayes_pls_golite062009
structural constituent of cytoskeleton 0.561294047948865 bayes_pls_golite062009
MAP kinase activity 0.507543102601882 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.424938382645604 bayes_pls_golite062009
transmembrane transporter activity 0.395297228560691 bayes_pls_golite062009
actin filament binding 0.245106394940513 bayes_pls_golite062009
protein complex binding 0.240494058155837 bayes_pls_golite062009
cyclin-dependent protein kinase activity 0.199802352672083 bayes_pls_golite062009
protein serine/threonine/tyrosine kinase activity 0.185239852962563 bayes_pls_golite062009
molecular transducer activity 0.150412261639747 bayes_pls_golite062009
signal transducer activity 0.150412261639747 bayes_pls_golite062009
magnesium ion binding 0.134608114107045 bayes_pls_golite062009
substrate-specific transporter activity 0.0793187210666157 bayes_pls_golite062009
MAP kinase kinase kinase activity 0.073383252842333 bayes_pls_golite062009
MAP kinase kinase activity 0.0583007878333612 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.00372971855400395 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [382-523]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DTDNSGTITL EELRQGLAKQ GTRLSEYEVQ QLMEAADADG NGTIDYGEFI AATMHINRLD  60
   61 REEHLYSAFQ HFDKDNSGYI TTEELEQALR EFGMNDGRDI KEIISEVDGD NDGRINYEEF 120
  121 VAMMRKGNPD PNPKKRRELS FK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 23.09691
Match: 2aaoA
Description: Regulatory apparatus of Calcium Dependent protein kinase from Arabidopsis thaliana
Matching Structure (courtesy of the PDB):

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