From Publication: | Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054 |
Notes: | Classifier used Gene Ontology annotations. [FDR: 0.038] [SVM Score: 0.677207787181] |
Complex Size: | 2 proteins |
Protein |
GO Cellular Component | GO Biological Process | GO Molecular Function |
DYN3 |
|
|
|
VIK1 |
|
|
|
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
microtubule associated complex | 7.7306E-6 | 2 | 18 | 2 | 6292 |
microtubule cytoskeleton | 2.8118E-4 | 2 | 106 | 2 | 6292 |
cytoskeletal part | 1.0156E-3 | 2 | 201 | 2 | 6292 |
cytoskeleton | 1.1732E-3 | 2 | 216 | 2 | 6292 |
cytoplasmic dynein complex | 1.2712E-3 | 2 | 4 | 1 | 6292 |
dynein complex | 1.2712E-3 | 2 | 4 | 1 | 6292 |
kinesin complex | 2.224E-3 | 2 | 7 | 1 | 6292 |
cytoplasmic microtubule | 4.4455E-3 | 2 | 14 | 1 | 6292 |
microtubule | 9.8303E-3 | 2 | 31 | 1 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
microtubule-based process | 3.0847E-4 | 2 | 111 | 2 | 6292 |
microtubule-based movement | 5.0798E-3 | 2 | 16 | 1 | 6292 |
microtubule-based transport | 5.0798E-3 | 2 | 16 | 1 | 6292 |
nuclear migration along microtubule | 5.0798E-3 | 2 | 16 | 1 | 6292 |
cytoskeleton-dependent intracellular transport | 5.7138E-3 | 2 | 18 | 1 | 6292 |
nuclear migration | 6.3477E-3 | 2 | 20 | 1 | 6292 |
nucleus localization | 6.3477E-3 | 2 | 20 | 1 | 6292 |
establishment of nucleus localization | 6.3477E-3 | 2 | 20 | 1 | 6292 |
mitotic sister chromatid cohesion | 7.2981E-3 | 2 | 23 | 1 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
motor activity | 7.7306E-6 | 2 | 18 | 2 | 6292 |
nucleoside-triphosphatase activity | 2.7262E-3 | 2 | 329 | 2 | 6292 |
hydrolase activity, acting on acid anhydrides | 3.1391E-3 | 2 | 353 | 2 | 6292 |
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 3.1391E-3 | 2 | 353 | 2 | 6292 |
pyrophosphatase activity | 3.1391E-3 | 2 | 353 | 2 | 6292 |
microtubule motor activity | 3.1764E-3 | 2 | 10 | 1 | 6292 |