From Publication: | Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054 |
Notes: | Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 0.696054610557] |
Complex Size: | 2 proteins |
Protein |
GO Cellular Component | GO Biological Process | GO Molecular Function |
SEN34 |
|
|
|
TRM1 |
|
|
|
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
nuclear inner membrane | 2.779E-6 | 2 | 11 | 2 | 6292 |
nuclear membrane | 2.3525E-4 | 2 | 97 | 2 | 6292 |
organelle inner membrane | 8.5997E-4 | 2 | 185 | 2 | 6292 |
nuclear envelope | 9.9543E-4 | 2 | 199 | 2 | 6292 |
tRNA-intron endonuclease complex | 1.5888E-3 | 2 | 5 | 1 | 6292 |
endomembrane system | 3.9918E-3 | 2 | 398 | 2 | 6292 |
envelope | 6.43E-3 | 2 | 505 | 2 | 6292 |
organelle envelope | 6.43E-3 | 2 | 505 | 2 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
tRNA processing | 1.7194E-4 | 2 | 83 | 2 | 6292 |
tRNA metabolic process | 3.6076E-4 | 2 | 120 | 2 | 6292 |
ncRNA processing | 1.1624E-3 | 2 | 215 | 2 | 6292 |
ncRNA metabolic process | 1.6621E-3 | 2 | 257 | 2 | 6292 |
RNA processing | 3.6384E-3 | 2 | 380 | 2 | 6292 |
tRNA methylation | 4.7627E-3 | 2 | 15 | 1 | 6292 |
tRNA splicing, via endonucleolytic cleavage and ligation | 5.0798E-3 | 2 | 16 | 1 | 6292 |
RNA splicing, via endonucleolytic cleavage and ligation | 5.0798E-3 | 2 | 16 | 1 | 6292 |
RNA methylation | 6.0308E-3 | 2 | 19 | 1 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
tRNA (guanine-N2-)-methyltransferase activity | 9.5344E-4 | 2 | 3 | 1 | 6292 |
tRNA-intron endonuclease activity | 1.5888E-3 | 2 | 5 | 1 | 6292 |
endoribonuclease activity, producing 3'-phosphomonoesters | 1.5888E-3 | 2 | 5 | 1 | 6292 |
tRNA (guanine) methyltransferase activity | 2.5415E-3 | 2 | 8 | 1 | 6292 |
endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters | 2.859E-3 | 2 | 9 | 1 | 6292 |
tRNA-specific ribonuclease activity | 4.7627E-3 | 2 | 15 | 1 | 6292 |
tRNA methyltransferase activity | 5.3968E-3 | 2 | 17 | 1 | 6292 |
N-methyltransferase activity | 7.9314E-3 | 2 | 25 | 1 | 6292 |
RNA methyltransferase activity | 8.248E-3 | 2 | 26 | 1 | 6292 |
endoribonuclease activity | 8.5646E-3 | 2 | 27 | 1 | 6292 |