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Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks to yield 3'-phosphomonoesters. Catalysis of the reaction: hydrolysis of the phosphodiester linkage between guanosine and adenosine residues at one specific position in 28S rRNA from rat ribosomes. Catalysis of the reaction: hydrolysis of poly(A), forming oligoribonucleotides and ultimately 3'-AMP. Catalysis of the hydrolysis of ester linkages within ribonucleic acids by creating internal breaks to yield 3'-phosphomonoesters. Catalysis of the endonucleolytic cleavage to 3'-phosphomononucleotides and 3'-phosphooligonucleotides with 2',3'-cyclic phosphate intermediates. Catalysis of the hydrolysis of phosphodiester bonds in chains of RNA. Catalysis of the endonucleolytic cleavage of RNA to 3'-phosphomononucleotides and 3'-phosphooligonucleotides ending in C-P or U-P with 2',3'-cyclic phosphate intermediates. Catalysis of the reaction: endonucleolytic cleavage of RNA precursor into two, leaving 5'-hydroxy and 3'-phosphate groups. Catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks. Catalysis of the endonucleolytic cleavage of pre-tRNA, producing 5'-hydroxyl and 2',3'-cyclic phosphate termini, and specifically removing the intron. Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks. Catalysis of the reaction: endonucleolytic cleavage to 2',3'-cyclic nucleotides. Catalysis of the reaction: two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides with 2',3'-cyclic phosphate intermediates. Catalysis of the reaction: two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides ending in Ap or Gp with 2',3'-cyclic phosphate intermediates.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: endoribonuclease activity, producing 3'-phosphomonoesters
Acc: GO:0016892
Aspect: Molecular Function
Desc: Catalysis of the hydrolysis of ester linkages within ribonucleic acids by creating internal breaks to yield 3'-phosphomonoesters.
Synonyms:
  • endoribonuclease activity, producing other than 5'-phosphomonoesters
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 74 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0016892 - endoribonuclease activity, producing 3'-phosphomonoesters (interactive image map)
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