From Publication: | Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054 |
Notes: | Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 0.726201948902] |
Complex Size: | 2 proteins |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
DNA-directed RNA polymerase II, holoenzyme | 7.7811E-5 | 2 | 56 | 2 | 6292 |
nucleoplasm part | 1.5102E-3 | 2 | 245 | 2 | 6292 |
nucleoplasm | 1.7541E-3 | 2 | 264 | 2 | 6292 |
Cdc73/Paf1 complex | 2.5415E-3 | 2 | 8 | 1 | 6292 |
holo TFIIH complex | 3.1764E-3 | 2 | 10 | 1 | 6292 |
nuclear lumen | 5.1728E-3 | 2 | 453 | 2 | 6292 |
transcription elongation factor complex | 7.2981E-3 | 2 | 23 | 1 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
transcription from RNA polymerase II promoter | 2.8267E-3 | 2 | 335 | 2 | 6292 |
histone methylation | 6.3477E-3 | 2 | 20 | 1 | 6292 |
transcription, DNA-dependent | 6.3792E-3 | 2 | 503 | 2 | 6292 |
RNA biosynthetic process | 6.5067E-3 | 2 | 508 | 2 | 6292 |
protein amino acid alkylation | 7.6148E-3 | 2 | 24 | 1 | 6292 |
protein amino acid methylation | 7.6148E-3 | 2 | 24 | 1 | 6292 |
transcription | 7.6839E-3 | 2 | 552 | 2 | 6292 |
DNA metabolic process | 8.631E-3 | 2 | 585 | 2 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
transcription regulator activity | 2.8947E-3 | 2 | 339 | 2 | 6292 |
RNA polymerase II transcription elongation factor activity | 4.1283E-3 | 2 | 13 | 1 | 6292 |
transcription elongation regulator activity | 6.0308E-3 | 2 | 19 | 1 | 6292 |