From Publication: | Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054 |
Notes: | Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 0.76275326636] |
Complex Size: | 2 proteins |
Protein |
GO Cellular Component | GO Biological Process | GO Molecular Function |
BNA4 |
|
|
|
GUT2 |
|
|
|
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
mitochondrial outer membrane | 2.1151E-4 | 2 | 92 | 2 | 6292 |
outer membrane | 7.9595E-4 | 2 | 178 | 2 | 6292 |
organelle outer membrane | 7.9595E-4 | 2 | 178 | 2 | 6292 |
mitochondrial membrane | 1.7808E-3 | 2 | 266 | 2 | 6292 |
mitochondrial envelope | 2.4514E-3 | 2 | 312 | 2 | 6292 |
integral to mitochondrial outer membrane | 4.1283E-3 | 2 | 13 | 1 | 6292 |
intrinsic to mitochondrial outer membrane | 4.1283E-3 | 2 | 13 | 1 | 6292 |
integral to mitochondrial membrane | 4.4455E-3 | 2 | 14 | 1 | 6292 |
mitochondrial part | 5.6881E-3 | 2 | 475 | 2 | 6292 |
envelope | 6.43E-3 | 2 | 505 | 2 | 6292 |
organelle envelope | 6.43E-3 | 2 | 505 | 2 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
NAD metabolic process | 1.5158E-5 | 2 | 25 | 2 | 6292 |
nicotinamide nucleotide metabolic process | 4.5626E-5 | 2 | 43 | 2 | 6292 |
pyridine nucleotide metabolic process | 5.2295E-5 | 2 | 46 | 2 | 6292 |
oxidoreduction coenzyme metabolic process | 8.6451E-5 | 2 | 59 | 2 | 6292 |
coenzyme metabolic process | 3.6076E-4 | 2 | 120 | 2 | 6292 |
nucleotide metabolic process | 4.1068E-4 | 2 | 128 | 2 | 6292 |
nucleoside phosphate metabolic process | 4.1068E-4 | 2 | 128 | 2 | 6292 |
cofactor metabolic process | 5.9526E-4 | 2 | 154 | 2 | 6292 |
nucleobase, nucleoside and nucleotide metabolic process | 6.1875E-4 | 2 | 157 | 2 | 6292 |
NAD biosynthetic process | 2.224E-3 | 2 | 7 | 1 | 6292 |
nicotinamide nucleotide biosynthetic process | 3.1764E-3 | 2 | 10 | 1 | 6292 |
pyridine nucleotide biosynthetic process | 3.811E-3 | 2 | 12 | 1 | 6292 |
NADH oxidation | 3.811E-3 | 2 | 12 | 1 | 6292 |
NADH metabolic process | 4.7627E-3 | 2 | 15 | 1 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
kynurenine 3-monooxygenase activity | 3.1786E-4 | 2 | 1 | 1 | 6292 |
glycerol-3-phosphate dehydrogenase activity | 3.1786E-4 | 2 | 1 | 1 | 6292 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen | 9.5344E-4 | 2 | 3 | 1 | 6292 |
oxidoreductase activity | 1.9877E-3 | 2 | 281 | 2 | 6292 |
monooxygenase activity | 2.224E-3 | 2 | 7 | 1 | 6292 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | 7.2981E-3 | 2 | 23 | 1 | 6292 |