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Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water. Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and one atom of oxygen is incorporated into one donor. Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced or incorporated into a donor. Catalysis of the reaction: L-kynurenine + NADPH + H+ + O2 = 3-hydroxy-L-kynurenine + NADP+ + H2O.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: kynurenine 3-monooxygenase activity
Acc: GO:0004502
Aspect: Molecular Function
Desc: Catalysis of the reaction: L-kynurenine + NADPH + H+ + O2 = 3-hydroxy-L-kynurenine + NADP+ + H2O.
Synonyms:
  • kynurenine hydroxylase activity
  • kynurenine 3-hydroxylase activity
  • L-kynurenine-3-hydroxylase activity
  • L-kynurenine,NADPH:oxygen oxidoreductase (3-hydroxylating)
Proteins in PDR annotated with:
   This term: 6 [Search]
   Term or descendants: 6 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004502 - kynurenine 3-monooxygenase activity (interactive image map)

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