From Publication: | Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054 |
Notes: | Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 0.80359777203] |
Complex Size: | 2 proteins |
Protein |
GO Cellular Component | GO Biological Process | GO Molecular Function |
HST1 |
|
|
|
PHO23 |
|
|
|
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
histone deacetylase complex | 1.2783E-5 | 2 | 23 | 2 | 6292 |
chromatin remodeling complex | 2.4511E-4 | 2 | 99 | 2 | 6292 |
nucleoplasm part | 1.5102E-3 | 2 | 245 | 2 | 6292 |
nucleoplasm | 1.7541E-3 | 2 | 264 | 2 | 6292 |
nuclear lumen | 5.1728E-3 | 2 | 453 | 2 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
negative regulation of mitotic recombination | 9.5344E-4 | 2 | 3 | 1 | 6292 |
regulation of mitotic recombination | 1.5888E-3 | 2 | 5 | 1 | 6292 |
negative regulation of DNA recombination | 3.811E-3 | 2 | 12 | 1 | 6292 |
regulation of DNA recombination | 4.7627E-3 | 2 | 15 | 1 | 6292 |
negative regulation of DNA metabolic process | 6.6645E-3 | 2 | 21 | 1 | 6292 |
chromosome organization | 7.7677E-3 | 2 | 555 | 2 | 6292 |
histone deacetylation | 8.5646E-3 | 2 | 27 | 1 | 6292 |
protein amino acid deacetylation | 9.1975E-3 | 2 | 29 | 1 | 6292 |
regulation of DNA metabolic process | 9.8303E-3 | 2 | 31 | 1 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
histone deacetylase activity | 2.5061E-5 | 2 | 32 | 2 | 6292 |
protein deacetylase activity | 2.5061E-5 | 2 | 32 | 2 | 6292 |
deacetylase activity | 3.0063E-5 | 2 | 35 | 2 | 6292 |
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides | 5.6994E-5 | 2 | 48 | 2 | 6292 |
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds | 1.5966E-4 | 2 | 80 | 2 | 6292 |
NAD-independent histone deacetylase activity | 2.224E-3 | 2 | 7 | 1 | 6292 |
NAD-dependent protein deacetylase activity | 2.859E-3 | 2 | 9 | 1 | 6292 |
NAD-dependent histone deacetylase activity | 2.859E-3 | 2 | 9 | 1 | 6292 |