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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 0.94906496638]
Complex Size: 2 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

RAVE complex 1.5158E-7 2 3 2 6292
CBF3 complex 1.2712E-3 2 4 1 6292
SCF ubiquitin ligase complex 3.4937E-3 2 11 1 6292
cullin-RING ubiquitin ligase complex 4.4455E-3 2 14 1 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

regulation of protein complex assembly 2.779E-6 2 11 2 6292
regulation of cellular component biogenesis 7.7306E-6 2 18 2 6292
pH reduction 1.3945E-5 2 24 2 6292
intracellular pH reduction 1.3945E-5 2 24 2 6292
vacuolar acidification 1.3945E-5 2 24 2 6292
regulation of intracellular pH 1.5158E-5 2 25 2 6292
regulation of cellular pH 1.5158E-5 2 25 2 6292
regulation of pH 2.0514E-5 2 29 2 6292
cellular monovalent inorganic cation homeostasis 2.8346E-5 2 34 2 6292
monovalent inorganic cation homeostasis 3.552E-5 2 38 2 6292
regulation of cellular component organization 1.4021E-4 2 75 2 6292
cellular cation homeostasis 2.7588E-4 2 105 2 6292
cation homeostasis 2.974E-4 2 109 2 6292
cellular chemical homeostasis 3.5475E-4 2 119 2 6292
cellular ion homeostasis 3.5475E-4 2 119 2 6292
cellular homeostasis 3.6076E-4 2 120 2 6292
chemical homeostasis 3.791E-4 2 123 2 6292
ion homeostasis 3.791E-4 2 123 2 6292
protein complex biogenesis 6.0304E-4 2 155 2 6292
protein complex assembly 6.0304E-4 2 155 2 6292
centromere complex assembly 9.5344E-4 2 3 1 6292
kinetochore assembly 9.5344E-4 2 3 1 6292
kinetochore organization 9.5344E-4 2 3 1 6292
macromolecular complex assembly 1.9877E-3 2 281 2 6292
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 2.224E-3 2 7 1 6292
protein neddylation 2.224E-3 2 7 1 6292
macromolecular complex subunit organization 3.2108E-3 2 357 2 6292
protein ubiquitination during ubiquitin-dependent protein catabolic process 3.4937E-3 2 11 1 6292
cellular component assembly 3.7349E-3 2 385 2 6292
homeostatic process 4.1951E-3 2 408 2 6292
regulation of biological quality 7.6561E-3 2 551 2 6292
regulation of exit from mitosis 7.9314E-3 2 25 1 6292
exit from mitosis 7.9314E-3 2 25 1 6292
G2/M transition of mitotic cell cycle 9.1975E-3 2 29 1 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

DNA replication origin binding 4.1283E-3 2 13 1 6292

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Created and Maintained by: Michael Riffle