| From Publication: | Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054 |
| Notes: | Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 0.950891495671] |
| Complex Size: | 2 proteins |
| Protein |
GO Cellular Component | GO Biological Process | GO Molecular Function |
| PDB1 |
|
|
|
| PDX1 |
|
|
|
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
| GO Term |
P-value |
A |
B |
I |
T |
| mitochondrial pyruvate dehydrogenase complex | 7.579E-7 | 2 | 6 | 2 | 6292 |
| pyruvate dehydrogenase complex | 7.579E-7 | 2 | 6 | 2 | 6292 |
| mitochondrial matrix | 7.7811E-4 | 2 | 176 | 2 | 6292 |
| mitochondrial lumen | 7.7811E-4 | 2 | 176 | 2 | 6292 |
| mitochondrial part | 5.6881E-3 | 2 | 475 | 2 | 6292 |
| nucleoid | 8.248E-3 | 2 | 26 | 1 | 6292 |
| mitochondrial nucleoid | 8.248E-3 | 2 | 26 | 1 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
| GO Term |
P-value |
A |
B |
I |
T |
| pyruvate metabolic process | 4.7798E-5 | 2 | 44 | 2 | 6292 |
| monocarboxylic acid metabolic process | 4.5024E-4 | 2 | 134 | 2 | 6292 |
| acetyl-CoA biosynthetic process from pyruvate | 6.3568E-4 | 2 | 2 | 1 | 6292 |
| acetyl-CoA biosynthetic process | 1.2712E-3 | 2 | 4 | 1 | 6292 |
| organic acid metabolic process | 2.793E-3 | 2 | 333 | 2 | 6292 |
| oxoacid metabolic process | 2.793E-3 | 2 | 333 | 2 | 6292 |
| carboxylic acid metabolic process | 2.793E-3 | 2 | 333 | 2 | 6292 |
| cellular ketone metabolic process | 3.0157E-3 | 2 | 346 | 2 | 6292 |
| acetyl-CoA metabolic process | 6.3477E-3 | 2 | 20 | 1 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
| GO Term |
P-value |
A |
B |
I |
T |
| pyruvate dehydrogenase (acetyl-transferring) activity | 1.2712E-3 | 2 | 4 | 1 | 6292 |
| pyruvate dehydrogenase activity | 1.2712E-3 | 2 | 4 | 1 | 6292 |
| oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor | 1.5888E-3 | 2 | 5 | 1 | 6292 |
| oxidoreductase activity, acting on the aldehyde or oxo group of donors | 7.9314E-3 | 2 | 25 | 1 | 6292 |