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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 0.950891495671]
Complex Size: 2 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

mitochondrial pyruvate dehydrogenase complex 7.579E-7 2 6 2 6292
pyruvate dehydrogenase complex 7.579E-7 2 6 2 6292
mitochondrial matrix 7.7811E-4 2 176 2 6292
mitochondrial lumen 7.7811E-4 2 176 2 6292
mitochondrial part 5.6881E-3 2 475 2 6292
nucleoid 8.248E-3 2 26 1 6292
mitochondrial nucleoid 8.248E-3 2 26 1 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

pyruvate metabolic process 4.7798E-5 2 44 2 6292
monocarboxylic acid metabolic process 4.5024E-4 2 134 2 6292
acetyl-CoA biosynthetic process from pyruvate 6.3568E-4 2 2 1 6292
acetyl-CoA biosynthetic process 1.2712E-3 2 4 1 6292
organic acid metabolic process 2.793E-3 2 333 2 6292
oxoacid metabolic process 2.793E-3 2 333 2 6292
carboxylic acid metabolic process 2.793E-3 2 333 2 6292
cellular ketone metabolic process 3.0157E-3 2 346 2 6292
acetyl-CoA metabolic process 6.3477E-3 2 20 1 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

pyruvate dehydrogenase (acetyl-transferring) activity 1.2712E-3 2 4 1 6292
pyruvate dehydrogenase activity 1.2712E-3 2 4 1 6292
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor 1.5888E-3 2 5 1 6292
oxidoreductase activity, acting on the aldehyde or oxo group of donors 7.9314E-3 2 25 1 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle